Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case is presented of a 38-year old woman who, when treated for alternating amenorrhea and menorrhagia with Lyndiol (.l5 mg mestranol and 5 mg lynestrenol, combined) became anxious and depressed and developed depigmentation and alopecia of her left eyebrow. She showed several symptoms of luteal insufficiency: menstrual disorders, spontaneous abortions, menometrorrhagia, and hyperplastic endometrium, a fter progestagen treatment. During a 6 month course of Lydiol she became severely depressed with short attention span, loss of memory, fatique, frigidity, obsessions and phobic behavior. Treatment with Antideprein (Tofranil) and Napoton (Librium) were not effective, but stopping Lyndiol improved the depression, frigidity, and partially improved the obsessive-phobic behavior. The disscussion centered on the role of monoamines in the depressions associated with oral contraceptives.
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PMID:[Syndrome of depression and depigmentation after administration of combined estrogen-progestagens]. 1225 82

This essay on the effects of modern effective contraception on psychological and sexual behavior concentrates on the characteristis of French society. Contraception is obviously a weapon against multiple illegal abortons, and a means for professional, social and sexual liberation of women. For physicians it provides a medium of interacting for the first time with the sexual life of patients, sometimes resulting in spectacular cures of psychosomatic disorders such as pelvic pain, menometrorrhagia, depression and anxiety. The opportunity for more frequent sexual relations, free of fear of pregnancy, may permit the release of orgasm and an experience of new sensation, authenticity and confidence for the woman. But contraception may also reveal or aggravate sexual dysfunction and participate in the deterioration of sexual adjustment. The physician must be aware of patients' prior psychosexual situation in order not to make contraception a scapegoat for so-called pill or IUD side effects. This requires sound medical training and a good doctor-patient relationship. For many young women maternity is the sign of womanhood, and for mature women and their partners, fertility is the essence of feminine attraction. This unconscious belief is often the basis for forgetting pills, frigidity, impotence and masochistic pregnancy. Children are unconsciously the bridge toward immortality.
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PMID:[Influence of contraception on psychology and sexual life]. 1230 76