Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Examples are reported of clinical cases confirming the difficulties of diagnosis of recurring form of thromboembolism of the minor pulmonary artery branches and the following leading signs of the disease are singled out: elevation of the temperature, tachy- and orthopnea, prolonged retrosternal pain, crepitation and moist rales over the lungs, inversion of the T-wave and depression of the ST segment in the right thoracic leads.
 ...
PMID:[Difficulties in the diagnosis of the recurrent form of thromboembolism of the pulmonary artery branches]. 260 18

Insomnia is highly prevalent in patients with chronic disease including chronic heart failure (CHF) and is a significant contributing factor to fatigue and poor quality of life. The pathophysiology of CHF often leads to fatigue, due to nocturnal symptoms causing sleep disruption, including cough, orthopnea, paroxysmal nocturnal dyspnea, and nocturia. Inadequate cardiac function may lead to hypoxemia or poor perfusion of the cerebrum, skeletal muscle, or visceral body organs, which result in organ dysfunction or failure and may contribute to fatigue. Sleep disturbances negatively affect all dimensions of quality of life and is related to increased risk of comorbidities, including depression. This article reviews insomnia in CHF, cardiac medication side-effects related to sleep disturbances, and treatment options.
 ...
PMID:Insomnia and chronic heart failure. 1875 45