Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An 8 to 10-week-old female New Zealand white rabbit, Oryctolagus cuniculus, which exhibited clinical signs of anorexia, depression, and torticollis was found to have lymphosarcoma with lymphoblastic leukemia. The multiple visceral involvement with neoplastic lymphoid cells observed in this animal was similar to previously reprted cases of lymphosarcoma in the rabbit. An unusual finding was the occurrence of lymphoblastic leukemia since lymphosarcoma in the rabbit has previously been reported as aleukemic.
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PMID:Lymphosarcoma with lymphoblastic leukemia in a New Zealand white rabbit. 27 19

Eastern equine encephalomyelitis (EEE) was the cause of heavy mortality in coturnix quail (Coturnix coturnix) reared commercially in South Carolina. The birds showed depression, tremor, and partial paralysis that advanced into complete paralysis, torticollis, and death within a few hours. The only consistent lesion on necropsy was a catarrhal enteritis in the duodenal area. The disease spread rapidly to all pens throughout the two houses on the farm in all birds over 2 weeks old, and mortality ranged from 40 to 90% in the various pens within the house. Total mortality exceeded 90,000 birds. Age groups on the farm ranged from 1 day to 8 weeks, at which time the birds went for slaughter. It appears that the initial infection was spread by cannibalism. EEE was diagnosed by isolating the virus in fertile eggs and suckling mice, with subsequent identification by complement-fixation. This is the first documented case of EEE in coturnix quail.
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PMID:Eastern equine encephalomyelitis outbreak in coturnix quail. 69 63

To explore suggested relationships between involuntary motor disorders and obsessive-compulsive disorder (OCD), we evaluated obsessive-compulsive characteristics in patients with idiopathic spasmodic torticollis (IST). Twenty-two patients with IST had significantly higher scores than 29 age- and sex-matched healthy controls on the Yale-Brown Obsessive-Compulsive Scale and the obsessionality subscale of the Symptom Checklist-90-Revised. The IST patients also had higher (though not significantly so) scores on the Maudsley Obsessive-Compulsive Inventory. Their Beck Depression Inventory scores were likewise higher than those of controls. These results provide additional support for the theory of a link between basal ganglia disorders and psychiatric disorders.
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PMID:Obsessive-compulsive characteristics in patients with idiopathic spasmodic torticollis. 149 58

The impact of botulinum toxin injection on psychological function was assessed in 26 patients with idiopathic torticollis. Eighty five per cent of the patients and 88% of the relatives considered torticollis to be better following the injections. Symptomatic improvement with the injections was associated with significant reduction of depression and disability, but non-significant improvement in body concept, and self-esteem. This concordant pattern of change in symptoms and psychological function with the injections supports the proposal that in torticollis depression and disability are consequences of the postural abnormality of the head.
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PMID:Psychological functioning before and after treatment of torticollis with botulinum toxin. 156 90

Successful treatment of torticollis with electromyographic (EMG) biofeedback has been reported in a number of single case and single group studies. The present investigation represents the first controlled outcome study. Twelve torticollis patients were randomly assigned to EMG biofeedback or relaxation training and graded neck exercises (RGP). The procedure involved three sessions of baseline assessment, 15 sessions of EMG BF or RGP, 6 sessions of EMG BF or RGP plus home-management, 6 sessions of home-management alone, and follow-up 3 months after the end of treatment. A variety of outcome measures were used including physiological (EMG from the two sternocleidomastoid muscles, skin conductance level), behavioral (angle of head deviation, range of movement of the head), and self-report (depression, functional disability, body concept), therapist and "significant other" reports and independent observer assessment of videos. In both groups, neck muscle activity was reduced from pre- to posttreatment. This reduction was greater in the EMG biofeedback group. There was evidence of feedback-specific neck muscle relaxation in the EMG biofeedback group. Therefore, the outcome was not due to nonspecific factors and could be attributed to feedback-specific effects. Changes in skin conductance level showed that neck muscle relaxation was not simply mediated by a general reduction of "arousal." Significant improvements of extent of head deviation, and range of movement of the head, as well as reductions of depression were present, which were not different in the two groups. At the end of treatment, no patient was asymptomatic. Any therapeutic benefit was generally maintained at follow-up. The results and the procedural simplicity of RGP make the issue of cost-efficacy of EMG biofeedback a pertinent one. Further controlled outcome studies of EMG biofeedback treatment of torticollis with larger samples are required.
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PMID:EMG biofeedback treatment of torticollis: a controlled outcome study. 176 Apr 62

Sixty-seven patients suffering from spasmodic torticollis, a neurological disorder in which involuntary contractions of the head produce an abnormal head posture, completed a booklet of questionnaires aiming to assess psychosocial adjustment. Twenty-four per cent of the patients were moderately to severely depressed. Overall, as a sample the patients were not acceptant of or adjusted to their illness. Cognitive and emotion-focused strategies were slightly more widely used than instrumental ways of coping. Both adaptive and maladaptive coping strategies were more frequently used by female than male sufferers. The number of individuals who were potential sources of social support was not high (mean = 2.7, SD = 1.2). The patients were, however, generally satisfied with the available support. Self-depreciation, lack of control over head position/movement and the resulting disability in activities of daily living, lack of satisfaction with available social support, and the use of maladaptive coping strategies accounted for 75% of the variance of depression in torticollis. Self-depreciation, which was the most salient predictor of depression in torticollis, accounting for 59% of its variance, was itself shown to arise from the patient's negative body concept relating to the postural abnormality of the head. As the severity of illness and resulting disability contributed to depression, successful symptomatic treatment of torticollis would be expected to ameliorate mood. However, as the currently available medical treatments are not effective for all treated cases, and as the self-depreciation resulting from a negative body concept formed the core of depression in torticollis, cognitive-behavioural therapy could improve the quality of life of the depressed torticollis patient.
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PMID:Psychosocial factors and depression in torticollis. 192 Jan 80

Encephalitozoonosis was identified for the first time in arctic lemmings (Dicrostonyx stevensoni and crosses of D. stevensoni and Dicrostonyx rubricatus). The most common clinical findings were circling, torticollis, posterior paralysis, depression, blindness and death related to parasitic granulomas in many tissues. Granulomas were most frequent in the central nervous system, but were seen in many other tissues throughout the body. Granulomas were characterized by collections of macrophages and varying numbers of lymphocytes and neutrophils with or without necrosis of parenchymal tissue. Most granulomas contained protozoon cysts with ultrastructural characteristics of Encephalitozoon cuniculi. Protozoon cysts were seen in vascular endothelium in many tissues accompanied by minimal or no inflammatory reaction.
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PMID:Encephalitozoonosis in arctic lemmings. 247 90

A disease outbreak characterized by torticollis, incoordination, and depression was seen in a commercial broiler operation in California. Listeria monocytogenes was isolated from brain tissue with some degree of difficulty, and only after culturing directly from the brain stem. No evidence of concurrent disease was found, and the source of the outbreak was undetermined.
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PMID:An encephalitic form of listeriosis in broiler chickens. 249 81

The authors report the result of surgery on a case of Parinaud's syndrome with a torticollis chin down of the Alajouanine type (the flexion of the head was used to allow an elevation of the eyes; from this position, depression was possible). A Fadenoperation on both medial recti aimed to suppress the convergence spasms. A resection of both superior recti aimed to substitute for the flexion of the head. The results clearly showed that it is possible to improve the oculo-motricity in a gaze palsy by substituting surgery for the compensatory reflexes. A Fadenoperation which does not destroy the previous parallelism in the primary position is a good indication for any convergence spasm.
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PMID:[Oculomotor surgery in Parinaud's syndrome]. 264 Oct 98

An 8-year-old boy presented with an ocular torticollis that had appeared many months after a ptosis repair. The three-step test was positive for a superior oblique palsy. However, at the time of surgery the forced duction test showed a marked restriction in depression of the eye. These findings were duplicated before the second procedure normalized the ocular movements. The surgical microscope was of great help for the extensive dissection necessary to correct the condition. The fourth step, the forced duction test, was essential for accurate differential diagnosis between true superior oblique palsy and a mechanical hypertropia.
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PMID:A four-step test for diagnosis of pseudo superior oblique palsy. 316 82


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