Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Neurologic alteration in 36 patients who had received either a sagittal split osteotomy, an intraoral vertical ramus osteotomy, or a mandibular vestibuloplasty was evaluated by questionnaire, detailed neurosensory examination, and personality testing. Subjective sensory alteration was reported by 69.4% of the entire group; neurosensory examination showed demonstrable neuropathy in 54% of the 72 nerve divisions that were examined, with the greatest incidence, 84.6%, in the group that had received sagittal split osteotomies. Personality testing indicated that dysesthetic patients experienced greater degrees of neuroticism and depression than did patients without pain.
 ...
PMID:Analysis of postsurgical neurologic alteration in the trigeminal nerve. 22 Apr

The drug treatment of terminally ill patients is reviewed. The treatment of the major discomforting symptoms of degenerative diseases--pain, anxiety, nausea, vomiting and depression--is reviewed. The use of phenothiazines, anticholinergic drugs and corticosteroids is discussed. To help patients keep track of their drugs, use of a medication schedule card is recommended.
 ...
PMID:Drug therapy in terminally ill patients. 23 20

It is proposed that injury may be followed by three phases of behaviour in human beings and animals. In the immediate phase, pain may not occur and other activities take precedence. Even when the victims are fully aware of their injury, these other activities may include fighting, escaping and obtaining safety and aid. Once relative safety from the source of injury has been achieved, a new form of behaviour related to allowing recovery begins. This is the acute stage. The need for the initiation of this behaviour is signalled by pain. In the transition stage from injury to the beginning of recovery, anxiety is a cardinal feature. The anxiety is directed at assuring safety from the original damage, at assuring the best conditions for the initiation of treatment and recovery, and at the possible future consequences of the damage. This phase merges with the third period, during which quiet inactivity is the optimal tactic to encourage cure and recovery. This third stage associated with pain and depression may appear prolonged far beyond the necessary period for recovery. It is proposed here that pain is associated with the search for treatment and optimal conditions for recovery.
 ...
PMID:Three phases of evil: the relation of injury to pain. 26 51

Nutritional therapy of the cancer patient by the oral route includes management of factors that may cause anorexia, attempts to modify the patient's eating behavior, and the offering of nutritional supplements to the patient. Anoretic factors for which specific strategies may be employed include taste abnormalities, pain, nausea, and depression. Modification of the patient's eating behavior involves patient education, monitoring, and feedback. Education includes nutritional instruction and instruction in favorable patterns for mealtime eating and stimulation of snack eating. Snack eating includes the use of nutritional supplements, and patient acceptance of commercially available supplements was studied. When synthetic chemically defined nutritional products were compared with milk-based product, patients preferred the milk-based product. Intercomparisons between milk-based products showed slight differences in preference ranking among these products and also differences between patients and controls in their relative order of ranking. Preference testing may be useful in assisting the health care team in selecting the optimal nutritional supplement to offer each patient.
 ...
PMID:Oral feeding in the nutritional management of the cancer patient. 26 17

The contribution of psychiatry to the evaluation and treatment of chronic pain is described. Psychological profiles may predict the outcome of surgery, while the psychiatric interview enhances understanding and may disclose formal psychiatric disorder. The measurement of pain is dependent on factors affecting pain complaint, and the psychiatrist can only accept the patient's experience. The reaction inhibition test and Chapman's Somatic, Anxiety, Depression (SAD) index provide ways of elucidating the functional versus organic dilemma. This is further understood by attention to the concepts of operant pain, the sick role, and illness behaviour. Psychotropic medications, psychotherapy, behaviour therapy, biofeedback, and distractional methods are the tools available to the psychiatrist. The patient's attitude and a combined physical and psychiatric approach are important for successful therapy.
 ...
PMID:Chronic pain and the psychiatrist. 27 40

The purposes of this study were to determine and evaluate the psychosexual behavior of selected patients whose jaws were immobilized. Data for this pilot study were collected by using a standardized interview protocol with ten patients whose jaws were immobilized. The interview questions were designed to ascertain whether sexual problems existed, the nature and management of these problems, and the suggested role the operating surgeon might assume in assisting the patient. The data revealed that sexual difficulties were experienced by nine of these patients, and many of their problems were similar. The chief complaints included: (1) shortness of breath during sexual intercourse, (2) difficulty in oral foreplay, (3) poor verbal communication, (4) altered self-image, (5) sexual dysfunctions induced by pain medication, (6) depression, and (7) a lack of ability to exercise oral-genital sexual contact. Nine of the ten patients agreed that the operating surgeon should inform his or her patients with immobilized jaws of potential sexual disability. We believe that additional studies of these problems could enhance the management of patients with oral and maxillofacial injuries.
 ...
PMID:Psychosexual dysfunction in patients with immobilized jaws. 28 Aug 45

A modified Krogh-Poulsen questionaire was used to study 210 patients with temperomandibular joint complaints. The patients were fitted with a biteplate. Pain at the pterygoideus lateralis muscle was noted in 59.6% of the patients. Constant improvement was demonstrable in 76% of the patients after a period of six months. The cracking in the joint was found in 51% of the patients resistant to therapy. The study of patients resistant to therapy indicated positive psychiatric findings in more than 80% of these patients. The diagnoses ranged from the beginning stages of depression to discovery of a basophilic adenoma.
 ...
PMID:[Evaluation of the effectiveness of the diagnosis and initial therapy by means of bite plates]. 28 1

A case report and review of the problem of duodenal leiomyoma are presented. Although these lesions are rare and usually asymptomatic, they can present with symptoms of hemorrhage, obstruction, pain, and perforation. Barium roentgenographic examination may show filling defects of compressive lesions. Angiography shows a hypervascular, encapsulated lesion. Endoscopy may reveal a submucosal mass with central depression. At operation, it is important to distinguish the benign leiomyoma from leiomyosarcoma.
 ...
PMID:Duodenal leiomyoma as a cause of gastrointestinal hemorrhage. 30 63

The efficacy of nefopam, a novel analgesic agent, was compared to pentazocine in a double blind study in 40 cancer patients with chronic pain. Both drugs were administered orally for 10 days. Pain relief after nefopam was at least as good as after pentazocine. Side efftects after nefopam were different in nature and less frequent than after pentazocine; respiratory depression or sedation were no observed.
 ...
PMID:[Analgesia with mild side effects]. 33 98

Of 6 outpatients with chronic pain, 5 completed therapy based on a 3-part treatment package designed to provide symptom control, stimulus control and social system modification. Each of the components of the treatment package resulted in therapeutic change. A mean of 35.8 weekly hour long therapy sessions resulted in statistically significant decreases in pain, hopelessness, depression and analgesic medication intake. Generally, these improvements were maintained at 6 months and 1 year follow-up. This study is consistent with the notion that chronic pain is maintained by a combination of inter- and intrapersonal factors. A controlled comparison of this treatment program with other treatments for chronic pain is indicated.
Pain 1978 Aug
PMID:A pilot study of the treatment of outpatients with chronic pain: symptom control, stimulus control and social system intervention. 35 68


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>