Gene/Protein
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Enzyme
Compound
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Gene/Protein
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Target Concepts:
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Enzyme
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Query: UMLS:C0011570 (
depression
)
172,036
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Obese female subjects with binge eating disorder
BED
; (N = 107) completed the Beck
Depression
Inventory, Symptom Checklist-90, Inventory of Interpersonal Problems, and Rosenberg Self-Esteem Scale. Subjects were divided into moderate or severe binger on the basis of scores on the Binge Eating Scale, and grouped into moderately or severely obese by performing a median split on their weights. Spearman correlational analyses were performed to determine the relationship between psychopathology and obesity and psychopathology and binge eating. Analyses of variance (ANOVAs) were then performed using scores on the psychological measures with subjects grouped both by severity of obesity and severity of binge eating. The results indicated that in our sample, obesity and scores on the measures of psychiatric symptomatology were unrelated. However, a significant positive relationship was found between binge eating severity and degree of psychiatric symptomatology. We suggest that binge eating may account for the observed relationship between obesity and psychopathology reported in previous studies. We discuss the importance of assessing
BED
when conducting research with obese individuals.
...
PMID:Obesity, binge eating and psychopathology: are they related? 812 27
This study explored the differences between bulimia nervosa ("BN," n=22) and binge-eating disorder ("BED," n=11) in type 1 diabetic females and the factors most predictive of poor glycemic control in patients suffering from these disorders. These two groups and a control group without eating disorders (n=32) were compared across a number of demographic, psychological, and medical variables. BN manifested significantly more severe disturbances related to eating disorders,
depression
, anxiety, a higher rate of co-occurring mental disorders, and poorer psychosocial functioning compared with
BED
. BN also showed poorer glycemic control. Multivariate analysis indicated that higher serum glycosylated hemoglobin (HbA1c) levels were most associated with the presence of severe insulin omission in type 1 diabetic females with binge eating. Clinicians may be able to determine the psychological/medical severity of illness in these patients by identifying the presence of compensatory behaviors to prevent weight gain such as severe insulin omission, as described in the DSM-IV.
...
PMID:Differences between bulimia nervosa and binge-eating disorder in females with type 1 diabetes: the important role of insulin omission. 1057 71
This pilot study examined (a) the effectiveness of short-term group relational therapy (RT) in comparison to short-term group cognitive-behavioral therapy (CBT), and (b) the relationship between perceived mutuality (PM) in relationships and severity of bulimic and depressive symptoms in women with bulimia nervosa (BN). Fifteen women ages 20-54 diagnosed with BN (n=11) or binge-eating disorder (
BED
, n=4) were randomly assigned to a 16-week manualized RT or CBT group. The following measures were administered at baseline, at 8 and 16 weeks, and at 6th- and 12th-month follow-ups: Eating Disorders Inventory-2 (EDI-2), Hamilton
Depression
Rating Scale (HDRS), Beck
Depression
Inventory (BDI), and the Mutual Psychological Development Questionnaire (MPDQ). A series of mixed design analyses of variance (ANOVA) were computed to examine group therapy effectiveness and outcomes related to PM and symptom severity. Both group RT and CBT treatment conditions showed significant improvement in reducing binge eating, vomiting, and
depression
at end of treatment and across follow-up assessment times. Low levels of PM with father at baseline were associated with high levels of bulimic and depressive symptoms across assessment times, whereas low PM with mother was only associated with high levels of
depression
. Pilot study findings supported the idea that group work focused primarily on PM and relational factors can be effective in treating women with bulimic and depressive symptoms. Findings also suggest that relationships with fathers play an important role in recovery.
...
PMID:The relationship between perceived mutuality and bulimic symptoms, depression, and therapeutic change in group. 1500 Sep 96
Dimensions of body image in a sample of obese women diagnosed with binge eating disorder (
BED
; N=42) were compared with a sample of obese women without
BED
(non-
BED
; N=42), matched on age and BMI. Additionally, the relationship between
BED
, body image and several dimensions of treatment response was examined. Results indicated
BED
women were more likely to negatively evaluate their global physical appearance and have less satisfaction with specific areas of the body than were non-
BED
women, even after controlling for
depression
scores. While
BED
women were significantly more likely to endorse depressive symptoms,
depression
scores were negatively correlated with body satisfaction in non-
BED
women only.
BED
women did not fare worse in formal weight-loss treatment, as measured by length of time in treatment, group-therapy attendance, or BMI at posttreatment. The role of body image in women with
BED
seeking weight-loss treatment is discussed relevant to the context of potential impact of
BED
and negative body image on active weight-loss treatment and maintenance.
...
PMID:Body image evaluations in obese females with binge eating disorder. 1500 Oct 59
Binge eating symptomatology affects African Americans and Caucasians at similar rates. Moreover, compared to anorexia nervosa (AN) and bulimia nervosa (BN), binge eating and
BED
are more evenly distributed across genders. Undergraduates are likely to be affected by binge eating, yet, relatively few studies have investigated this behavior and its correlates in college samples. This study examined the influence of alexithymia,
depression
, and anxiety on binge eating among ethnically diverse undergraduates. Results indicated that these variables significantly predicted eating symptomatology among Caucasian and African American women but not among Caucasian men. Further, among Caucasian women,
depression
was the only unique predictor of eating pathology. In contrast, anxiety was the only unique predictor of disordered eating in African American women. There were no differences between Caucasians and African Americans in severity of disordered eating symptomatology; however, in both ethnic groups, women reported greater eating pathology than men. Eating disorders of all types may be more prevalent among African American undergraduates than previously thought. These results highlight the need to study binge eating and its correlates in this traditionally underserved group.
...
PMID:Binge eating and psychological distress in ethnically diverse undergraduate men and women. 1509 85
Bariatric surgery is an increasingly utilized treatment for severe obesity, especially among women. Although African American women have high rates of severe obesity, most research investigating psychological correlates of obesity has been conducted with Caucasians. This study examined the characteristics of African American women seeking bariatric surgery, and ethnic differences in
BED
rates and correlates of binge eating. Finally, we examined whether the association between psychological factors associated with binge eating was moderated by ethnicity. Results indicated that African American women had higher BMIs, higher self esteem, and less
depression
than Caucasians. There were no differences in rates of binge eating or
BED
. Both
depression
and self esteem accounted for unique variance in binge eating; however, these relationships were not moderated by ethnicity. These results further highlight African Americans' vulnerability to EDs, and suggest that
depression
and low self esteem are equally relevant to binge eating in African American and Caucasian women.
...
PMID:Binge eating among African American and Caucasian bariatric surgery candidates. 1585 65
Bariatric surgery is an increasingly popular treatment for severe obesity. However, while rates of obesity are comparable across genders, women are much more likely to undergo bariatric surgery. Little research exists on gender differences among bariatric surgery candidates. This study examined gender differences and their correlates within a sample of 487 patients presenting for bariatric surgery. Results indicated that women were more depressed than men, dieted more, and were more likely to report that their weight interfered with feeling good about themselves. There were no differences in
BED
rates or binge eating. Furthermore, among women, both
depression
and self-esteem were associated with binge eating symptomatology. However, among men, only
depression
contributed to binge eating scores. These findings provide evidence for the significance of binge eating and
depression
among both male and female bariatric surgery candidates.
...
PMID:Gender and binge eating among bariatric surgery candidates. 1636 Jun 22
The moderating influence of binge eating status on obese individuals' responses to weight loss treatment was evaluated with a meta-analysis of 36 tests of weight loss treatment (n=792) that were matched to control key background variables. After controlling for pre-treatment weight, treatment produced more weight loss in samples of obese non-
BED
compared with obese
BED
participants. Weight loss treatment produced large posttreatment reductions in
depression
in both obese
BED
and non-
BED
samples. The results indicate that
BED
status moderated post-treatment weight loss among people in weight treatment programs. Obese
BED
(average weight loss=1.3 kg) samples lost negligible weight compared to obese non-
BED
(average weight loss=10.5 kg) samples.
BED
status did not moderate psychological responses to treatment: both
BED
and non-
BED
samples experienced large post-treatment reductions in
depression
. The clinical implications of these findings are discussed.
...
PMID:Responses to weight loss treatment among obese individuals with and without BED: a matched-study meta-analysis. 1761 89
This study compared rates of self-reported childhood maltreatment in three groups diagnosed using semi-structured interviews: binge eating disorder (
BED
; n=176), night eating syndrome (NES, n=57), and overweight/obese comparison (OC, n=38). We used the Childhood Trauma Questionnaire (CTQ) to assess childhood maltreatment and the Beck
Depression
Inventory-II to assess
depression
levels. Reports of maltreatment were common in patients with
BED
(82%), NES (79%), and OC (71%). The
BED
group reported significantly more forms of maltreatment above clinical cut-points (2.4) than the OC (1.4) group but not the NES (1.8) group. The
BED
and NES groups reported more emotional abuse than the OC group. A higher proportion of the
BED
group reported emotional neglect and a higher proportion of the NES group reported physical neglect.
Depression
levels, which were higher in
BED
and NES than OC, were associated with higher levels of physical and emotional abuse and neglect. In conclusion, reported rates of physical and sexual abuse differed little across groups, whereas reports of neglect and emotional abuse were higher in the
BED
and NES groups than in the OC group and were associated with elevated
depression
levels.
...
PMID:High self-reported rates of neglect and emotional abuse, by persons with binge eating disorder and night eating syndrome. 1765 55
We examined whether body weight,
depression
, and body dissatisfaction could predict problematic eating behaviors in a community sample of less acculturated adult Latina women. Three hundred and forty-nine Latina women ages 20-40 were classified as non-overeater (n=244), eating disorder not otherwise specified-binge eating disorder features (EDNOS-BED) (n=65), or eating disorder not otherwise specified-bulimia nervosa features (EDNOS-BN) (n=40). Participants completed measures of problematic eating behaviors,
depression
, and body image. Results revealed that normal weight and overweight women were at a higher risk only for EDNOS-BN, while obese women were at a higher risk for either EDNOS-BN or EDNOS-
BED
. Women with high
depression
scores were 16 times more likely to be assigned to the EDNOS-BN group than women with lower
depression
scores. Results illustrate the important role of
depression
and body weight in predicting problematic eating in less acculturated Latinas.
...
PMID:Correlates of problematic eating behaviors in less acculturated Latinas. 1832 96
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