Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
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Query: UMLS:C0011570 (
depression
)
172,036
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
To investigate an hypothesized link between unwanted sexual experiences in childhood and later problems with eating, 21 survivors of sexual abuse completed three questionnaires: the Eating Attitudes Test, the Sexual Events Questionnaire, and the General Health Questionnaire. These women scored high on the
EAT
, and scores were higher for women who reported more sexual experiences. A similar relation was found between number of sexual experiences and
depression
, and anxiety and insomnia, but not with somatic symptoms. The implications of these findings for intervention in sexual abuse and eating disorder cases are discussed.
...
PMID:Eating attitudes in survivors of unwanted sexual experiences. 160 Apr 4
The influence of an in vivo treatment with optimally tumor-inhibiting doses of cis-diamminedichloroplatinum(II) (DDP), titanocene dichloride (TDC), and vanadocene dichloride (VDC) on the DNA distribution pattern, determined by pulse-cytophotometry, and on the mitotic activity of
EAT
cells is investigated. Whereas DDP causes an immediate and long-lasting decrease of mitoses but no disturbances of the
EAT
cell kinetics, a marked G2 block with a maximum at 10-12 h a. t. and an irreversible and extensive mitotic
depression
is evoked by TDC. In the case of DDP and TDC, the tumor cells are removed several days a. t. by cells belonging to the defensive system of the host animals. In contrast, VDC induces partially synchronized waves after a transient suppression of mitoses and reversible cell accumulation in the late S and in the G2 phases. Additionally, 5-16% of the cells become polyploid after VDC treatment.
...
PMID:Cytokinetic behavior of Ehrlich ascites tumor after in vivo treatment with cis-diamminedichloroplatinum(II) and metallocene dichlorides. 719 26
The Eating Disorders Inventory (EDI I) has been applied to four groups of patients with Eating Disorders (ED): Anorexic Bulimic Subtype (AB N = 22), Anorexic Restrictive Subtype (AR N = 36); Bulimic (B N = 51) and Other Eating Disorders (OED N = 15), according to the DSM III-R criteria. We have also applied the Eating Attitude Test (
EAT
-40), the Beck
Depression
Inventory (13 items), the Hamilton Anxiety Rating Scale and the Hamilton
Depression
Rating Scale. During their hospital care, the patients have been treated by cognitive-behavioural therapy. The order or decreasing total scores in EDI at the admission is the B subtype, then the AR subtype, then the OED group. In total score, the B and AB improved more than the order groups, between their admission and a second assessment three months later. Body dissatisfaction, Drive for thinness and Interpersonnal distrust are the only subscales for which no group showed a statistical improvement after three months. The B group decreased more in the subscale, than the other groups, particularly in Interoceptive awareness, Ineffectiveness and bulimia.
...
PMID:[Measuring the development of eating disorders in a group of patients with the Eating Disorders Inventory (EDI)]. 766 14
The results of a small pilot study using Fluvoxamine (Faverin) in the treatment of non-vomiting bingeing female patients and women with bulimia nervosa is presented. Ten non-vomiting subjects and six with bulimia nervosa were treated on an open basis with Fluvoxamine 100-200 mg daily. Assessment was made using established questionnaires for severity of eating disorder and abnormality of mood. Five non-vomiting patients and three with bulimia nervosa completed the study. Non-vomiters showed a significant weight loss; a significant reduction in number of binges; a significant reduction in the scores on the BITE and the
EAT
; and a significant reduction in anxiety. Those with bulimia nervosa had a significant reduction in hunger and a reduction in
depression
which tended towards significance. Firm conclusions cannot be drawn from this study as it is an open pilot study of a small number of women. However, the results indicate that Fluvoxamine may have a role in the treatment of eating disorders where bingeing is a prominent symptom and that further research would be valuable. Comments are also made on the usefulness of various questionnaires designed to assess eating disorders.
...
PMID:Fluvoxamine: an open pilot study in moderately obese female patients suffering from atypical eating disorders and episodes of bingeing. 838 40
A variety of sociocultural, familial and individual features associated with the eating disorders were examined in subjects with full syndrome (FS) and partial syndrome (PS) eating disorders and in normal high school students. The
EAT
-26 was administered to 995 high school students. This was followed by individual interviews with those who scored in the symptomatic range. Fifty-one students with PS eating disorders, 57 students without eating disorders (normal controls) and 30 hospital patients with FS, anorexia nervosa or bulimia nervosa were compared on subscales of the Eating Disorder Inventory, the Diagnostic Survey for Eating Disorders and the Beck
Depression
Inventory. The three groups displayed statistically significant differences on dimensions of EDI subscales Ineffectiveness and Interoceptive Awareness and also with respect to
depression
, history of being overweight and past history of emotional problems, as well as having mothers with medical illnesses. On these characteristics, the FS subjects displayed higher levels than the PS subjects, who in turn were higher than the NC subjects. The PS subjects displayed elevations on Body Dissatisfaction (EDI subscale), past medical illnesses, and mother's over-concern with eating and weight. These data support a continuum model of the eating disorders, but a continuum of multiple associated features rather than of dieting.
...
PMID:The relationship of partial syndrome eating disorders to anorexia nervosa and bulimia nervosa. 858 99
This study statistically tested six hypothesized risk factors of the model for anorexia nervosa. Forty-three adolescents with anorexia nervosa and 85 controls were administered the
EAT
, EDI, and FES. In addition, 43 parents of anorexics and 85 parents of controls completed the Family History Data Sheet, the FES, and the Perfect Child Questionnaire. Three of six hypothesized risk factors were confirmed: family history of
depression
, feelings of ineffectiveness, and poor interceptive awareness. Log-linear analysis indicated that the hierarchical model that best fit the data had significant two-way interactions with anorexia nervosa, G2 (11, N = 128) = 65.87, p < .001. In addition, alcohol and drug abuse or dependence figured prominently in the family history of patients with anorexia nervosa. The multidimensional model for anorexia nervosa holds up as an exploratory model of this condition in the adolescent age group.
...
PMID:Testing the hypothesis of the multidimensional model of anorexia nervosa in adolescents. 910 95
Social physique anxiety (SPA) is highly correlated with other body image measures that have been considered to be important in understanding eating disorders. However, SPA has not been directly studied with respect to eating disorders. Thus, the purpose of this investigation was to examine the link between SPA and measures of eating disorder symptomatology to determine if SPA should be considered as an additional risk factor in the prediction of eating disturbances. One hundred and sixty female undergraduates completed questionnaires measuring body mass index (BMI), social physique anxiety (SPAS), anorexic symptoms (
EAT
), bulimic symptoms (BULIT-R),
depression
(CES-D), self-esteem (SES) and obligatory exercise (OEQ). Regression analyses revealed that SPA and
depression
were the psychological correlates that predicted bulimic symptomatology and that SPA,
depression
, and obligatory exercise predicted anorexic symptomatology; all variables were positively related to eating disorder symptoms. Overall, the results indicate that social physique anxiety appears to be a useful construct for understanding eating disorder symptoms in female undergraduates.
...
PMID:Social physique anxiety and disordered eating: what's the connection? 946 35
This study examined the relative efficacy of a brief-psychoeducational treatment approaches for bulimia nervosa. Our sample comprised 26 women who sought consecutively treatment at the Eating Disorders Outpatient Unit. All subjects met DSM-IV criteria for Bulimia nervosa. For the assessment were used commonly applied questionnaires in the fiel of eating disorders such as: Eating Attitudes Test (
EAT
-40), Eating Disorders Inventory (EDI) and the Beck
Depression
Inventory (BDI). Outcome measures included also change in vomiting and binge-eating episodes per week. Each patient was assessed before and after a 6 weeks brief psychoeducational group therapy. At posttreatment, 30% of the patients were abstinent from binge eating-purging and 62% reduced their weekly frequency in binge eating and 56% reduced their weekly frequency in vomiting. Good-outcome (
EAT
scores < 30) was observed in more than 35% of our patients. The authors sought to identify factors that differentiate bulimic patients who improve while receiving treatment from those who do not.
...
PMID:[Psychoeducative ambulatory group in bulimia nervosa. Evaluation of a short-term approach]. 954 33
The aim of this study was to verify the link between psychopathological disorders and eating attitude in a clinical sample of 195 female obese subjects. A battery of psychological tests, including the Italian versions of the MMPI2, ASQ and
EAT
scales were administered to all the patients. We analyzed the link between psychopathological traits and eating attitudes by using both Multiple Regression analysis and non-parametric Segmentation Modeling. The results showed that psychopathological aspects, and
depression
in particular, are strongly linked to the eating attitude of clinically obese subjects. This is an important result also for therapeutic purposes, as it highlights the need for psychological support in diet therapy to intervene on the psychological perceptions and experiences of the patient.
...
PMID:Obesity, psychopathology and eating attitudes: are they related? 1072 54
Group therapy is generally recognized as an important form of psychotherapy for anorexia nervosa patients, but there are few controlled studies of its effectiveness. The aim of the current study was to determine the effectiveness of cognitive-behavioural therapy (CBT) for the treatment of anorexia nervosa in outpatients. Twenty-six outpatients with anorexia nervosa, were assessed for
depression
(BDI, Beck
Depression
Inventory), eating psychopathology (EDI, Eating Disorders Inventory), eating attitudes (
EAT
, Eating Attitudes Test) and weight at the beginning and at the end of the treatment and at one year follow-up. Our results substantiate the effectiveness of the CBT approach as a treatment and also at one year follow-up. Good
EAT
scores were observed in 70% of our cases after the treatment and in 60% at follow-up. Further research should assess the effectiveness of therapeutic groups more intensively because of their economic advantages.
...
PMID:Outpatient group therapy for anorexia nervosa: a preliminary study. 1123 49
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