Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

After the suicide of a 43-year-old woman with known depression, a 41-year-old paraplegic man who recently developed diarrhoea and a 41-year-old woman with probable depression with symptoms of psychosis, the general practitioners of the surviving relatives offered a sympathetic ear, answered questions and prescribed sedatives and/or follow-up counselling. Completed suicide occurs 1500 times each year in the Netherlands and is strongly associated with psychiatric morbidity as well as psychological features like hopelessness and inability to solve problems. Generally, this irreversible act ofdespair can lead to existential difficulties in surviving relatives. Following a loss, acceptance of reality is essential to initiating effective emotional processing. The general practitioner is often first and foremost involved in providing support and comfort to bereaved families, during which many questions about the cause of death are brought up. The general practitioner helps the family to reconstruct the rationale behind the suicide in order to initiate effective emotional processing. In addition, the general practitioner can assess the risk of psychiatric morbidity, including suicidal behaviour, in surviving relatives.
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PMID:[Relief for surviving relatives following a suicide]. 1680 69

Completed suicide and suicide attempts are major issues in the management of bipolar disorders. There is evidence that suicide rates among these patients are more than 20-fold higher than the general population and, furthermore, suicidal behavior is much more lethal in bipolar disorder than in the general population. Patients with mood disorders may sometimes exhibit highly perturbed mixed states, which usually increase the risk of suicide. Such states are particularly frequent in bipolar II patients, especially if patients are treated with antidepressant monotherapy (unprotected by mood stabilizers), when depression switches into mania (or vice versa), or when depression lifts and functioning approaches normality. Researchers worldwide agree that treatment involving lithium is the best way to protect patients from suicide risk. Psychosocial activities, including psychoeducation, can protect bipolar patients either directly or, more probably, indirectly by increasing adherence to treatment and helping in daily difficulties that otherwise may lead to demoralization or hopelessness. An extensive understanding of the psychosocial circumstances and the psychopathology of bipolar patients (including temperament) may help clinicians describe the clinical picture accurately and prevent suicidal behavior in these patients.
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PMID:Assessment and treatment of suicide risk in bipolar disorders. 1910 73