Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

30 patients with "Anxiety disorder" were investigated with regard to their psychosocial experiences, their family history, the course of their illness, and their interpersonal relationships using a semi-structured interview. Patients with panic disorder significantly more frequently reported real fright of a parent than did patients with generalized anxiety disorder. Both groups showed a high degree of secondary depression and avoidance behavior in the course of their illness. Chronic anxiety was more frequent in patients with generalized anxiety disorder. The difference in the perception and judgement of anxiety clearly demonstrates the significance of attribution. Since the patient with panic disorder externalizes his anxiety, he has periods of complete remission, whereas the patient with generalized anxiety disorder internalizes his anxiety, thus experiencing it as an ego-syntonic feature, with which he cannot cope.
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PMID:[Anxiety neurosis--avoidant behavior--depression. A comparison between panic disorder and generalized anxiety disorder]. 844 96

Maternal anxiety and family disruption are the two problems most often reported for families caring for an infant with apnea and inhome monitoring. With a diagnosis of apparent life-threatening event (ALTE) related to apnea, the parents have experienced finding their infant limp, motionless, appearing to not breathe, and with a color described as pale, blue, or marble white. Chronic anxiety in care-giving parents results in maternal depression. A growing body of evidence supports the view that both maternal anxiety and depression are potentially detrimental to the emotional development of infants. The purpose of this work was to investigate factors that impact maternal coping and parental adaptation outcomes related to infant apnea. The theoretical models for development of this review are anxiety and its disorders, and the family resiliency model of stress, adjustment, and adaptation.
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PMID:Indices for maternal/family anxiety and disruption related to infant apnea and home monitoring. 911 73

Owing to the potentially devastating effects of trauma-induced depression, explaining the relationship between trauma and depressive symptoms is important. In this study, we measured lifelong exposure to potentially traumatic events and depressive symptoms in 370-female undergraduates. We also measured anxiety, past negative time perspective and dissociation as potential mediators. Trauma exposure and depressive symptoms were related with a small but significant effect size (r = .16). Trauma was not associated with dissociation. We found that past negative time perspective and anxiety were full statistical mediators of this trauma-depressive symptoms relationship. These two mediators combined accounted for all of the variance in that association. Anxiety accounted for more of the variance than past negative time perspective. A proposed explanation is that trauma both affectively elevates anxiety and cognitively creates an enduring focus on the events. Chronic anxiety and a past negative time perspective may lead to depression over time. The clinical implications are possible explanations as to why some treatments work.
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PMID:Full statistical mediation of the relationship between trauma and depressive symptoms. 2716 90