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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Among a sample of 767 high utilizers of health care, 51% were identified as distressed by an elevated score on the SCL anxiety and depression scales, the SCL somatization scale, or by their primary-care physician. These distressed high utilizers were found to have a high prevalence of chronic medical problems and significant limitation of activities caused by illness. In the prior year, they made an average of 15 medical visits and 15 telephone calls to the clinic. The Diagnostic Interview Schedule was completed on 119 distressed high utilizers randomly assigned to an intervention group in a controlled trial of psychiatric consultation. The following DSM-III-R disorders were most common: major depression 23.5%, dysthymic disorder 16.8%, generalized anxiety disorder 21.8%, and somatization disorder 20.2%. Two thirds had a lifetime history of major depression. The examination resulted in an improved diagnostic assessment for 40% of intervention patients and a revised treatment plan for 67%.
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PMID:Distressed high utilizers of medical care. DSM-III-R diagnoses and treatment needs. 224 19

A small group of persons in ambulatory care settings report multiple symptoms and recurrent distress and utilize a high percentage of resources. Often these high utilizers are requesting help with a psychosocial problem through their symptoms. The psychosocial reason for high utilization of services may be a major psychiatric problem such as a somatization disorder or a depression/anxiety disorder. Most often, however, the person is seeking help with family or work stresses or is in need of information and/or reassurance. A careful assessment by the occupational health nurse can lead to a determination of an unmet psychosocial need. Direct help with this problem can break the cycle of multiple symptoms, distress, and utilization.
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PMID:Psychosocial assessment of the high utilizer of occupational health services. 230 11

The authors administered the Diagnostic Interview Schedule to 21 patients with borderline personality disorder. The patients met criteria for various other DSM-III diagnoses, meeting exclusion criteria in some cases, and not in other cases. Frequency distribution of each diagnosis and the diagnoses of each individual patient, are presented. Affective disorder was the most common diagnosis (85%). Of these, 62% had primary major depression, and 23% had secondary depression. Other diagnoses include bipolar disorder, dysthymia, panic, agoraphobia, alcohol and Drug abuse, somatization disorder, and many others. The authors conclude that while borderline disorder may be a sub-affective disorder, a specific diagnostic profile for this disorder that accounts for the presence of other Axis I and Axis II syndromes has yet to be delineated.
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PMID:Associated diagnoses (comorbidity) in patients with borderline personality disorder. 232 83

Somatization disorder (SD) is a syndromatic classification that allows a physician to identify more easily patients with a lifelong history of chronic subjective physical complaints that are unverified by objective examinations either at the time of initial presentation or during the subsequent five years. The somaticizing process is believed to be an expression of emotional distress. The most common complaints of SD patients include recurrent pain (site and quality vary), conversion (pseudoneurologic) symptoms, nervousness or depression (or both), sexual and marital discord, and, often, menstrual difficulties. Such patients will generally have a history of repeated hospitalization or surgery. These symptoms are not perceived as mild or unimportant but lead to physician consultation, prescription drug use, and modification of life-style. Such patients are prone to "doctor-shopping" and self-medication and are at risk for many iatrogenic illnesses. Because they generally are resistant to psychologic explanations for their condition, management aimed at protecting them from the consequences of their behavior is important. A heightened threshold for instituting aggressive diagnostic and treatment procedures is necessary.
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PMID:Somatization disorder. 266 8

Treatment of psychiatric disorders among the elderly is complicated by such factors as high incidence of medical illness and changes in drug metabolism; electroconvulsive therapy (ECT) is considered a reasonable treatment alternative for the elderly for several psychiatric syndromes. The authors review indications, complications, and precautions related to ECT for older patients. The primary indication is major depression; about 80 percent of elderly patients respond favorably. ECT appears less effective for depression secondary to dementia or somatization disorder. Although ECT is relatively safe for the elderly, up to one-third may experience a complication that interferes with treatment. Careful pre-ECT medical evaluation is essential, with special attention to cardiovascular factors and to concurrent medications.
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PMID:Electroconvulsive therapy for the elderly: a review. 304 87

The symptoms of irritable bowel syndrome (IBS) are usually a subset of a broader problem that meets DSM-III criteria for depression, anxiety disorder, somatization disorder, or adjustment disorder. A biopsychosocial perspective that addresses multigenerational family patterns of anxiety, depression, and somatization of stress suggests guidelines for understanding and treating patients with IBS symptoms. Effective treatment focuses primarily on helping patients cope with emotional disorders and psychosocial stressors, and secondarily on direct symptom relief. Psychotherapy is a valuable adjunct to medical treatment. The medications most likely to yield lasting benefits are the antidepressants.
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PMID:Irritable bowel syndrome. Toward a biopsychosocial systems understanding. 304 2

The concentration of thyrotropin-releasing hormone (TRH), a tripeptide (pyroglutamylhistidylprolin-amide), in the CSF of drug-free patients with DSM-III major depression, somatization disorder, and peripheral neurological disorders was measured with a sensitive and specific radioimmunoassay. The depressed patients had markedly higher CSF TRH concentrations than the other patient groups, and this finding could not be attributed to any demographic variables. The elevation of TRH in CSF provides further evidence of hypothalamic-pituitary-thyroid dysfunction in depression.
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PMID:Elevation of immunoreactive CSF TRH in depressed patients. 314 69

There has been controversy concerning the type and amount of psychosocial maladjustment among the siblings of children with chronic physical health problems and disabilities. Most previous studies have been conducted in clinical populations, often from tertiary care centers. This paper reports the risks of psychiatric disorders and social adjustment problems of the siblings of chronically ill children found in the Ontario Child Health Study (OCHS). The OCHS was a general population survey of 3,294 children, 4-16 years of age, living in 1,869 randomly selected families in the Province of Ontario, Canada. A 2-fold risk in emotional disorders, including depression, anxiety, and obsessive-compulsive disorder, and a 1.6-fold increase in risk in poor peer relationships were found. However, risks for conduct disorder, somatization disorder (measured only in 12- to 16-year olds), attention deficit disorder-hyperactivity, and one or more psychiatric disorders were not elevated. Moreover, no increased risks of adjustment problems, including social isolation, low participation in leisure activities, low competence in usual childhood recreational activities or school problems, were observed. Clinicians treating chronically ill children should assess the mental health and adjustment of their siblings without an expectation bias that problems will be found.
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PMID:The Ontario Child Health Study: social adjustment and mental health of siblings of children with chronic health problems. 340 27

Of 60 women with somatization disorder (SD), 54 (90%) met DSM-III criteria for a major affective episode. This group with secondary affective disorder (SAD) was compared with 29 women who had primary affective disorder (PAD). SAD patients reported significantly more symptoms, more psychiatric admissions, more and longer episodes of depression; more had attempted suicide, and more had made multiple attempts. SAD patients had often been hospitalized and were likely to have been treated with lithium and a variety of antidepressants. Studying relatively homogeneous primary psychiatric diagnoses facilitates the identification of distinctions between SAD and PAD patients.
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PMID:Secondary affective disorder in women with somatization disorder. 340 95

Studies using a variety of diagnostic rating scales have identified much higher levels of somatic symptoms in Hispanic psychiatric patients, particularly those with a diagnosis of schizophrenia or depression, than in their Anglo counterparts. However, this cultural difference cannot be generally demonstrated by using DSM-III somatoform disorders criteria. Many patients with "unfounded" somatic symptoms have another DSM-III primary diagnosis that is often assumed to cause or explain the somatic symptoms. In addition, the true prevalence of unfounded somatic symptoms is hidden because of the strict criteria required for a DSM-III primary diagnosis of somatization disorder. The author believes a more inclusive notion of somatization should be developed that would substantiate the presence of this trait among different populations and, if operationalized, would facilitate research on this important phenomenon. This is relevant not only because of the cross-cultural variability of somatization traits but also because they may become a salient feature of the primary syndrome and determine the use of clinical services. He proposes a new operational definition of somatization that encompasses the trait concept.
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PMID:Cross-cultural aspects of the somatization trait. 355 42


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