Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hymenolepis diminuta infection of Tenebrio molitor is associated with an impairment of vitellogenesis and a reduction in host fecundity. In this communication the effect of infection upon an additional aspect of host reproduction, the initiation of mating behavior, has been examined. Copulatory release pheromone, extracted from control virgin females 6-7 days old, was shown to stimulate a positive mating response in 88% of 5- to 6-day-old control males; however, only a 56% response was elicited by pheromone from infected females. In addition, parasitization adversely effected male response to pheromone from control females. A significant (P less than 0.001) depression of copulatory response occurred in infected 6- to 7-day-old males (age of peak response) although this effect was not sustained in older beetles. The possibility that an endocrine interaction between metacestodes and host may mediate these effects is discussed in the light of our knowledge of the role of host juvenile hormone in controlling both pheromone production and vitellogenesis in T. molitor.
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PMID:Metacestode-induced depression of the production of, and response to, sex pheromone in the intermediate host Tenebrio molitor. 188 25