Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper views conflict in Alzheimer's caregiving families as a multidimensional construct. Three conceptually distinct dimensions of family conflict are described and examined in relation to depression and anger. Regression analyses indicate that conflicts involving family members' attitudes and actions toward the caregiver are associated with increased risk for depression among caregivers, whereas conflicts stemming from family members' attitudes and behaviors toward the patient are most likely to result in anger. Self-concepts and normative expectations are implicated as key explanatory variables.
 ...
PMID:Conflict in Alzheimer's caregiving families: its dimensions and consequences. 142 77

The omission of the Wiggins Content Scales occurred because of the number of items deleted as well as the addition of items to the MMPI-2. The purpose of this study is to compare scorings of the items on the Wiggins Scales of the MMPI and the items that remain on these scales on the MMPI-2. The scales of Religious Fundamentalism and Authority Conflict appear to be those most seriously affected by the item change on the MMPI-2. The scales Depression and Family Conflict maintained all of their items, and the remaining nine were not found to be statistically different when the two scorings were compared.
 ...
PMID:Wiggins Content Scales and the MMPI-2. 157 22

This study investigated the influences of social support and interpersonal conflict on chronic pain in patients with arthritis or with myofascial disorders. Measures of social support, conflict, and pain were drawn from subscales of the McGill Pain Questionnaire, the Multidimensional Pain Inventory, the Family Environment Scale, and the Interpersonal Relationship Inventory. Patients with myofascial disorders reported significantly worse pain (sensory and affective), higher depression scores, more interpersonal conflict, and less support from others than patients with arthritis, but did not differ from them on personality traits. Also, the contributions of conflict to pain were found to depend on the nature of the chronic disorder and on the source of the conflict, i.e., significant other, family, or social network members. For patients with arthritis, less intense pain (sensory and affective) was associated with higher family conflict. Less intense sensory pain in arthritis was also associated with more punishing responses from the significant other to pain. For patients with myofascial disorders, more intense affective pain was associated with higher social network conflict. Social support did not significantly contribute to pain for either group. Thus, chronic painful disorders may differ on the influences that social relationships have on pain. The implications of these differences for treatment are discussed.
 ...
PMID:The contributions of interpersonal conflict to chronic pain in the presence or absence of organic pathology. 203 87

Suicide is a major public health problem among adolescents. Although the event is rare, and rates have stabilized and even shown slight reduction in recent years, suicide has nevertheless become the second leading cause of morbidity among youths aged 15 to 24, which is otherwise a robust and relatively disease-free population. Although research on predictive factors has yielded increasingly sensitive indices of who the high-risk adolescent might be, the inherent difficulty of predicting rare events from common ones has made sensitive and specific prediction most elusive. Current neurobiologic research holds promise for the use of biologic markers in the identification of high-risk adolescents, and pharmacologic research may yield further advances in the treatment of affectively disordered youths. At this point, the most promising approaches to treating adolescent suicide appear to be (1) treatment of disorders antecedent to suicide crises, such as depression, substance abuse, family conflict, and conduct disturbance, and (2) prevention efforts targeting known high-risk groups, such as affectively disordered young men with accompanying alcohol and drug involvement and other antisocial behavior.
 ...
PMID:Adolescent suicide. 220 55

Forty-two suicidal and 14 nonsuicidal affectively ill adolescent psychiatric inpatients were compared with respect to clinical phenomenology and measures of cognitive distortion, social skills, and familial-environmental stress. The suicidal group had an earlier onset and longer duration of affective illness and greater self-rated depression. The suicidal group also evinced greater cognitive distortion, less assertiveness, a greater likelihood of both a history and exposure to familial suicidality, and more life stressors within the 12 months prior to hospitalization. Among those suicidal patients who presented with a suicide attempt, suicidal intent was related to "double depression," comorbidity with substance abuse or conduct disorder, lack of assertiveness, family conflict, and family history of suicidal behavior. Early identification and treatment of affectively ill youth that target the above-noted domains may prevent much of the associated morbidity and mortality due to suicidality.
 ...
PMID:Suicidality in affectively disordered adolescent inpatients. 238 93

Little is known about the effects of psychosocial factors on the long-term course of unipolar depression. This article examines the 4-year stability and change in life stressors, social resources, and coping, and their effect on the course of treated unipolar depression among 352 men and women. Depressed patients were assessed at treatment intake and at 1-year and 4-year follow-ups. Over the 4 years, patients improved in symptom outcomes, the quality of social resources, and coping responses; there were some declines in life stressors. Life stressors, social resources, and coping were related to patient functioning concurrently, after controlling for demographics, initial treatment, and initial dysfunction severity. Preintake medical conditions and family conflict consistently predicted poorer long-term outcomes. The findings imply that medical conditions and family conflict are important risk factors that predict poorer long-term outcome of depression.
 ...
PMID:Life stressors, social resources, coping, and the 4-year course of unipolar depression. 259 82

In a study of 47 intact families with two same-sex children, associations among parental depression, marital satisfaction, family conflict, and inconsistent child rearing practices were examined, both between parents and within individual parents. Results are discussed in terms of gender-related differences in family process. The need for further research on father-child interactions is highlighted.
 ...
PMID:Marital quality, depression, and inconsistent parenting: relationship with observed mother-child conflict. 292 25

Stressors in the family and job environments have been proposed to play a role in the modulation of pain, yet direct empirical support for such a role is limited. The present study investigated the relationship between general stress, family and work environments (perceived social climate), psychological distress (anxiety, depression), and pain experience (sensory, affective, evaluative) in 33 ambulatory chronic low back pain (CLBP) subjects and 35 healthy controls matched for age, sex, socioeconomic status (SES), weight, and height. Results indicated that environmental stressors/social climate measures, including family conflict, family control, and general stress (Social Readjustment Rating Scale), were greater in the CLBP group. Distress measures were also higher in the CLBP group. Characteristics of the family and work environments were found to be more predictive of the affective and evaluative dimensions of pain. Increased family conflict was associated with increased distress and increased pain, while increased family independence was correlated with less distress and increased pain. Less peer cohesion, less physical comfort, and less job clarity were correlated with increased pain, but not distress. Work pressure was associated with decreased depression and less pain. These findings suggested the presence of both stress and operant mechanisms in the modulation of pain in the family, while operant and distraction mechanisms appear to characterize the relationship among work environment factors and pain.
 ...
PMID:Environmental stressors and chronic low back pain: life events, family and work environment. 316 37

In the aftermath of deinstitutionalisation and the move to community management of schizophrenia, relatives play an increasing role in the management of the illness. Families often complain of being misinformed and ill equipped to aid in the treatment. A supportive/educational intervention for relatives is described and evaluated. Seven parents with a schizophrenic offspring participated in a descriptive pilot study employing a pre-post-treatment design. To test the hypotheses that treatment would impact on participants' distress, burden, family conflict, isolation and knowledge of schizophrenia, before and after measures were taken on self-report indices utilising these features. Generalisation effects on family coping were assessed via tri-weekly telephone interviews for the duration of the study. The intervention included information and sharing sessions. There was a substantial reduction in distress symptoms, anxiety, depression, burden and the amount of family conflict; there was an increase in the duration of home visits, out of home excursions and knowledge of schizophrenia. Most of the subjects' needs were met by the intervention. These gains were achieved with a high level of consumer acceptance. It was concluded that this kind of education has an important role in psychosocial intervention with relatives of the mentally ill.
 ...
PMID:Family care and schizophrenia: the effects of a supportive educational program on relatives' personal and social adjustment. 344 52

Psychological assessments were conducted for Black and Latino sexually abused girls aged 8 to 13 years. Latino girls received significantly higher scores for depression than the Black girls. These differences in depression appeared to be related to ethnic differences in the circumstances of the abuse. Latino girls were abused at a younger age; more likely to be abused by a relative; and more likely to have had a sibling abused. Latinos were also more likely to report high levels of family conflict and somewhat lower levels of maternal support. Ethnicity was also found to be related to psychological functioning independently of the impact of other factors such as the circumstances of the abuse. Cultural and social factors that may influence psychological functioning subsequent to sexual abuse among Black and Latino girls are identified and discussed.
 ...
PMID:Ethnic differences in psychological functioning among black and Latino sexually abused girls. 755 38


1 2 3 4 5 6 7 8 9 10 Next >>