Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To determine whether poor sleepers have a unique personality constellation significantly different from that of good sleepers, a sample of 162 emotionally disturbed adolescent poor sleepers was compared to a sample of 153 emotionally disturbed adolescent good sleepers on standardized personality instruments. Poor sleepers were found to have a high incidence of neurotic psychopathology with personality patterns characterized by depression, fearfulness, inhibition, anxiety, and rumination. In contrast, good sleepers showed quasi-healthy and/or characterological patterns. While this study does not resolve cause and effect relationships, it does establish a highly significant relationship between neuroticism and sleep disturbance for adolescent boys and girls, and also demonstrates a similarity of personality dynamics and patterns between adult and adolescent samples of patients with sleep disturbances.
 ...
PMID:Personality patterns of adolescent poor and good sleepers. 46 12

A low NDF drought-stressed 1988 alfalfa silage (32.6% NDF) and a higher fiber 1988 alfalfa silage (46.4% NDF) were fed to lactating cows to evaluate effects on feed intake, fat test, and chewing behavior. Two groups of Holstein cows, 16 primiparous housed in tie stalls and 16 multiparous in free stalls, were assigned to diets based on parity and milk yield. The low NDF silage was fed for 6 wk in a TMR with 21.5% NDF and was compared with a TMR with 31.9% NDF. During an additional 4-wk period, one-half of each dietary group was fed a ration in which one-half of each silage was rechopped to reduce particle size. All rations contained a 1:1 ratio of forages to concentrates (DM basis) and were fed for ad libitum intake. Diets with 21.5% NDF and reduced particle size had no influence on milk fat percentage, 4% FCM yield, or plasma glucose. Cows fed these diets had reduced chewing time, due largely to decreased rumination time. Rumination and total chewing times per unit DMI and FCM also were lowest on these diets. Intake of DM on a BW basis was lowest for cows fed the low NDF rechopped silage diet. Cows fed in tie stalls had more eating bouts than those in free stalls, but total eating times were similar. Sufficient amounts of effective fiber appeared to be present in low NDF and rechopped silage diets to prevent the systemic events leading to milk fat depression but not to prevent a reduction in chewing time.
 ...
PMID:Effect of fiber content and particle size of alfalfa silage on performance and chewing behavior. 165 45

The 30-item Maudsley Obsessional-Compulsive Inventory (MOCI) was administered to 183 normal English-speaking Chinese subjects. The inventory achieved modest to relatively low internal consistency as a scale and as four subscales. Three independent dimensions of obsessional complaints interpretable as Perfectionistic and Repetitive Checking, Fear of Contamination, and Doubting Rumination emerged in the factor analysis of item responses. While the first factor corresponded to the Checking component, the second to the Cleaning component, the third was reminiscent of the Doubting, Ruminating and Slowness components. The responses to the MOCI were also explored in their correlations with depression and assertiveness. These results were discussed in in terms of the development of a refined and shortened version of the MOCI and their implications for developing differential treatment models for obsessive-compulsive patients.
 ...
PMID:The Maudsley Obsessional-Compulsive Inventory: a psychometric investigation on Chinese normal subjects. 225

The effects of different types of responses to a depressed mood on the duration and severity of the mood were examined. On the basis of Nolen-Hoeksema's (1987) response styles theory of depression, it was hypothesized that distracting, active responses would be more effective in alleviating a depressed mood than would ruminative, passive responses. A depressed mood was induced in 35 male and 34 female Ss, and subjects were randomly assigned to engage in 1 of 4 types of responses: an active task that distracted them from their mood; a passive, distracting task; an active task designed to lead to ruminations about their mood; or a passive, ruminative task. As predicted, the greatest remediation of depressed mood was found in Ss in the distracting-active response condition, followed in order by the distracting-passive, ruminative-active, and ruminative-passive response conditions. Degree of rumination had a greater impact on remediation of depressive affect than level of activity, with greater rumination leading to lesser remediation of depressive affect. In addition, the effects of the response tasks were limited to depressed mood. The implications of these results for interventions with depressed persons are discussed.
 ...
PMID:Effects of responses to depression on the remediation of depressive affect. 232 41

Alternate feeds are a major resource of the dairy industry. The major issue involving them is a method to predict accurately nutritive value from laboratory analyses. Variation in nutrient content of most alternate feeds is greater than in feed grains. Another issue is which depression factors to use in adjusting values for TDN from maintenance to production intakes. The NRC uses an average depression of 8% for all feeds; others think each feedstuff should be depressed individually, and discount factors have been proposed. For some alternate feeds, large differences in net energy estimates occur. Neutral detergent fiber has been proposed as an indicator of productive energy, but it has several deficiencies with alternate feeds high in fat, molasses, or ash. A summative equation based on fat, ash, protein, NDF, and lignin has wider application for predicting NE1 for all feeds. A roughage value index reflects a feed's property to stimulate chewing and rumination. Its use has special relevance for alternate feeds with small particle sizes, which may induce little chewing. Supplemental fat may increase the metabolizable energy converted to milk, but respiration experiments are needed.
 ...
PMID:Supplying the energy and fiber needs of dairy cows from alternate feed sources. 303 20

The rumination syndrome is defined as a process in which a person chews regurgitated gastric contents and then either partially ejects or swallows them. We report 12 cases of rumination in which the clinical diagnosis was supported by esophageal and gastrointestinal motility studies. These patients showed a characteristic pressure spike-wave pattern that was associated with regurgitation and was recorded simultaneously at all manometric sites. These spike waves increased significantly in frequency (p less than 0.001) and amplitude (p less than 0.04) during the postprandial period. The underlying gastrointestinal motility was normal except for a small decrease in postprandial antral motility index, with mean (+/- SE) values of 13.2 +/- 0.3 for patients compared with 14.2 +/- 0.3 for eight healthy adult controls (p less than 0.03). Nine patients had significant personality disturbances, including six whose scores on the Minnesota Multiphasic Personality Inventory for hypochondriasis and depression were significantly above the reference population (p less than 0.02). The rumination syndrome should be considered in adult patients with long-standing postprandial vomiting. The manometric pattern is characteristic.
 ...
PMID:The rumination syndrome in adults. A characteristic manometric pattern. 375 57

Sixteen sheep, each fitted with cannulas in the rumen and proximal duodenum, were given four diets in the chopped or ground and pelleted form, at fixed intakes at intervals of 2 h. The sheep were closely shorn and exposed to temperatures of 22-25 degrees or 1-4 degrees for four periods of 45 d. Flow of duodenal digesta by reference to the markers CoEDTA and 103Ru-phenanthroline, chewing behaviour and particle size of rumen and duodenal digesta were measured. Apparent digestibility of organic matter (OM) in the gastrointestinal tract was depressed (P less than 0.05) by grinding and pelleting the diet, and by exposure of sheep to cold ambient temperatures. This was attributable to depression (P less than 0.01) by 0.1 of OM digestion in the reticulo-rumen. No effects on intestinal digestion of OM were observed. Cold ambient temperatures did not affect the content, but increased the rate of digestion for pelleted diets but not for chopped diets, of potentially-degradable cell-wall constituents of ground dietary material incubated in nylon-bags in the rumen. Retention times of markers of the particulate and liquid phases of rumen digesta were not significantly (P less than 0.05) affected by ambient temperature, despite significant (P less than 0.001) increases in the rate of contraction of the reticulum. Retention time of 103Ru-phenanthroline in the intestines was not affected by cold exposure. Cold exposure was associated with depression (P less than 0.05) of volatile fatty acids concentration in the rumen and elevated (P less than 0.05)pH. Molar proportions of acetic and isovaleric acid were reduced (P less than 0.01), accompanied by increased (P less than 0.001) proportions of propionic acid during cold exposure. Cold exposure and pelleting of the diets were both associated with reduction in digesta particle size in the rumen. Duodenal particle size was not affected by cold exposure. Pelleting of the diet markedly reduced (P less than 0.001) duration of chewing and number of chews/d during eating and rumination. Cold exposure of sheep resulted in a faster (P less than 0.01) rate of eating of the diets. When allowed to express their voluntary feed consumption during a 10 d period, intakes of chopped diets were increased by 0.13 (P less than 0.01) by cold exposure, in contrast to lack of significant change in sheep given pellets.(ABSTRACT TRUNCATED AT 400 WORDS)
 ...
PMID:Influences of cold exposure on digestion of organic matter, rates of passage of digesta in the gastrointestinal tract, and feeding and rumination behaviour in sheep given four forage diets in the chopped, or ground and pelleted form. 406 59

Eleven ways in which people might react to life stress were studied in a sample of 576 Edinburgh women. For each item the subjects were asked whether they had reacted that way in general in the past 6 months and whether they had reacted in that way in response to any specific life stresses they had experienced. Being angry with oneself, being angry with others, rumination, use of alcohol, and use of tobacco all discriminated between those who were well and those who were psychiatrically ill at first interview and these items were formed into a 6-point scale of maladaptive reaction, based largely on specific response. The researchers conducted a follow-up analysis of 306 women who were well at first interview, 35 of whom suffered a psychiatric illness episode (23 depression, 12 anxiety) within the subsequent year. Maladaptive reaction at interview one predicted later illness inception, even after taking life stress into account. Several extraneous variables were considered, none of which could explain this effect. Maladaptive reaction seemed sometimes to lead to illness even when there was only minimal later life stress. Attempts to find coping reactions which afford protection against illness inception were unsuccessful.
 ...
PMID:Maladaptive coping reactions to stress. A study of illness inception. 406 93

Mild, delimited, and adaptive depression may be a specific example of a more general class of mechanism by which intelligent systems--individual, social, and artificial--adapt to dynamic, uncertain, and dangerous environments. Computer modeling, based on connectionist and artificial intelligence planning and learning programming techniques, supports this hypothesis by generating both adaptive behavior and analogs for 10 phenomena associated with depression: global, stable, and internal failure explantation, a cognitive loop of failure rumination, decreased motivation, self-esteem, and self-efficacy, and increased realism, negative generalization, and cognitive change. The idea of adaptive depression can be applied to more than one level of living systems. A better understanding of normal and adaptive depression may lead to a better understanding of clinical depression.
 ...
PMID:Computer modeling of adaptive depression. 748 63

In a longitudinal study of 253 bereaved adults, people with poorer social support, more concurrent stressors, and higher levels of postloss depression reported more rumination than people with better social support, fewer stressors, and lower initial depression levels. Women reported more rumination than men. People with a ruminative style at 1 month were more likely to have a pessimistic outlook at 1 month, which was associated with higher depression levels at 6 months. People with a more ruminative style were more depressed at 6 months, even after controlling for initial depression levels, social support, concurrent stressors, gender, and pessimism. Additional stressors and high depression scores at 1 month were also associated with higher levels of depression at 6 months.
 ...
PMID:Ruminative coping with depressed mood following loss. 804 85


1 2 3 4 5 6 7 8 9 10 Next >>