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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mental health disorders in adolescence are pervasive, often carry into adulthood, and appear to be inversely associated with social status. We examine how structural aspects of neighborhood context, specifically, socioeconomic stratification and racial/ethnic segregation, affect adolescent emotional well-being by shaping subjective perceptions of their neighborhoods. Using a community-based sample of 877 adolescents in Los Angeles County, we find that youth in low socioeconomic status (SES) neighborhoods perceive greater ambient hazards such as crime, violence, drug use, and graffiti than those in high SES neighborhoods. The perception of the neighborhood as dangerous, in turn, influences the mental health of adolescents: the more threatening the neighborhood, the more common the symptoms of depression, anxiety, oppositional defiant disorder, and conduct disorder. Social stability and, to a lesser extent, social cohesion, also emerge as contributors to adolescent disorder. This investigation demonstrates that research into the mental health of young people should consider the socioeconomic and demographic environments in which they live.
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PMID:The neighborhood context of adolescent mental health. 899 86

Structural equation modeling was used to test a theoretical model in which family cohesion and family reframing coping were hypothesized as mediators between family drinking problems, multiple risk factors, negative life events, and child mental health (conduct disorder, depression, anxiety) in two-parent families. Family cohesion mediated the relationships of family drinking problems and negative life events to child conduct disorder and depression. Negative life events mediated the relationships of family drinking problems and family multiple risk to child conduct disorder. Family reframing coping did not function as a mediator nor was it related to child mental health when other factors were considered simultaneously. Results indicate that increasing family cohesion and reducing sources of stress within the family (negative life events) represent promising areas of interventions for children with problem-drinking parents.
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PMID:Family characteristics as mediators of the influence of problem drinking and multiple risk status on child mental health. 914 93

Reliability of the Dominic-R, a questionnaire combining visual and auditory stimuli, was tested in 340 community children aged 6 to 11 years. Test-retest reliability of symptoms of, and symptom scores of, DSM-III-R disorders including simple phobias, separation anxiety disorder, overanxious disorder, depression/dysthymia, attention deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder was assessed. Most symptoms yielded kappas greater than .40, and ICCs ranged from .74 to .81. In conclusion, reliability of the Dominic-R compares favourably with that of other child assessment questionnaires.
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PMID:Reliability of the Dominic-R: a young child mental health questionnaire combining visual and auditory stimuli. 931 81

This summary of the practice parameters describes the diagnosis, treatment, and prevention of conduct disorder in children and adolescents. The rationales for these recommendations are based on a review of the scientific literature and clinical consensus, which are contained in the complete document. Clinical features of youths with conduct disorder include predominance in males, low socioeconomic status, and familial aggregation. Important continuities to oppositional defiant disorder and antisocial personality disorder have been documented. Extensive comorbidity, especially with other externalizing disorders, depression, and substance abuse, has been documented and has significance for prognosis. Clinically significant subtypes exist according to age of onset, overt or covert conduct problems, and levels of restraint exhibited under stress. To be effective, treatment must be multimodal, address multiple foci, and continue over extensive periods of time. Early treatment and prevention seem to be more effective than later intervention.
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PMID:Summary of the practice parameters for the assessment and treatment of children and adolescents with conduct disorder. 933 62

These practice parameters address the diagnosis, treatment, and prevention of conduct disorder in children and adolescents. Voluminous literature addresses the problem from a developmental, epidemiological, and criminological perspective. Properly designed treatment outcome studies of modern psychiatric modalities are rare. Ethnic issues are mentioned but not fully addressed from a clinical perspective. Clinical features of youth with conduct disorder include predominance in males, low socioeconomic status, and familial aggregation. Important continuities to oppositional defiant disorder and antisocial personality disorder have been documented. Extensive comorbidity, especially with other externalizing disorders, depression, and substance abuse, has been documented and has significance for prognosis. Clinically significant subtypes exist according to age of onset, overt or covert conduct problems, and levels of restraint exhibited under stress. To be effective, treatment must be multimodal, address multiple foci, and continue over extensive periods of time. Early treatment and prevention seem to be more effective than later intervention.
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PMID:Practice parameters for the assessment and treatment of children and adolescents with conduct disorder. American Academy of Child and Adolescent Psychiatry. 933 68

Although fluoxetine might be more effective than placebo for treating adolescent depression without major comorbidity, little is known about the response of depressive symptoms to antidepressants in adolescents with comorbid conduct disorder (CD) and substance use disorders (SUD). Male adolescents, who remained or became depressed after > or = 1 month of abstinence from abused substances during residential treatment for SUD, were treated in an open trial for > or = 7 weeks with a fixed dose of 20 mg of fluoxetine. The eight adolescents (ages 14-18 years) with CD, SUD, and major depression were not in drug withdrawal or receiving other pharmacotherapy. A > or = 50% improvement was observed in mean scores on Ten Point Depression Scale rated by clinician (p < 0.01) and patients (p < 0.01), Carroll Self-Ratings for depression (p < 0.02), and Severity of Illness scores on the Clinical Global Impression (p < 0.01). Of the eight adolescents, seven showed marked improvement and wished to continue fluoxetine after the trial. Side effects were mild and transient. No subject required dosage reduction or discontinuation of medication because of side effects. Fluoxetine appeared useful in treating substance-dependent delinquents whose major depressions persisted or emerged after 4 weeks of abstinence. These preliminary findings justify a controlled trial in such youths.
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PMID:Fluoxetine in drug-dependent delinquents with major depression: an open trial. 933 94

A large number of adolescents of interracial ancestry (parents comprising various combinations of African-American, American Indian/Alaska Native, European-American, Chinese, Filipino, Hispanic, Japanese, Korean, Puerto Rican, Samoan, and Tongan ancestry) were contrasted with a monoracial European-American sample in the degree to which they reported symptoms of depression, anxiety, conduct disorder/aggression, and substance abuse. The adolescents of interracial ancestry were subdivided into three groups in terms of parental ancestry: both parents of interracial ancestry, one parent of interracial and the other of monoracial ancestry, and both parents of monoracial but different ancestries. The interracial ancestry groups did not differ significantly from one another or from the European American sample in terms of symptom scores.
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PMID:Psychiatric symptoms in offspring of within vs. across racial/ethnic marriages. 940 72

This study uses information collected on two occasions from a probability sample of families with 5- to 12-year-old children (N = 1151) participating in a general population study in 1983 and follow-up in 1987. It evaluated the importance of maternal bias in the assessment of child behavior by comparing the relative strengths of association between maternal depression and childhood behavior and between maternal depression and mother reporting errors. Conduct problems and hyperactivity were measured as latent criterion variables constructed from mother, teacher, and youth (aged 12 to 16 years) ratings and their associations with maternal depression were modeled using covariance structure analysis. The analyses revealed that maternal depression was associated significantly with conduct problems (phi = .35) and hyperactivity (phi = .38) among 5- to 7-years-olds in 1983 but not 4 years later in 1987. None of the associations between maternal depression and mother reporting errors were significant. Among 8- to 12-year-olds in 1983, maternal depression was associated significantly not only with conduct problems (phi = .17) and hyperactivity (phi = .15) but also with mother rating errors of these behaviors (psi = .13 and .17, respectively). Four years later in 1987 when this cohort was 12 to 16 years old, the only significant association was between maternal depression and conduct disorder (phi = .25). Although evidence exists for associations between maternal depressed mood and mother rating errors, there also appears to be a substantive association between maternal depression and childhood behavior.
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PMID:Influence of maternal depressive symptoms on ratings of childhood behavior. 942 48

Levels of adult distress and ad lib alcohol consumption following interactions with child confederates were investigated in parents of children with no diagnosable psychiatric disorders. Sixty parents (20 married couples and 20 single mothers) interacted with boys trained to enact behaviors characteristic of either normal children or "deviant" children with externalizing behavior disorders--attention-deficit hyperactivity disorder (ADHD), conduct disorder (CD), and oppositional defiant disorder (ODD). Relative to the normal child role, interactions with deviant confederates were rated as significantly more unpleasant, resulted in feelings of role inadequacy, and produced significantly more anxiety, depression, and hostility. After the interactions, parents were given the opportunity to drink as much of their preferred alcoholic beverage as they desired while anticipating a second interaction with the same child. The participants consumed more alcohol following exposure to deviant as opposed to normal confederates.
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PMID:Effects of deviant child behavior on parental distress and alcohol consumption in laboratory interactions. 942 49

This investigation extends the earlier research by Archer and Gordon (1988) by examining the extent to which combining indices from the newly released MMPI-A and the revised Rorschach Comprehensive System furnishes incremental validity in terms of improved diagnostic prediction. The predictive accuracy of selected MMPI-A and Rorschach variables conceptually related to diagnoses of depression and conduct disorder were compared in a clinical sample of 152 adolescents. Results of multivariate analyses of variance revealed some significant differences between diagnostic groups on several MMPI-A scales, and 1 significant difference on the Rorschach involving the Vista variable. Stepwise discriminant function analyses resulted in 2 MMPI-A scales and 2 Rorschach variables that collectively accounted for a small proportion of variance in the diagnosis of depression, and 3 MMPI-A scales that accounted for a significant component of variance in the conduct disorder diagnosis. Classification accuracy results indicated that the hit rate for depression diagnosis did not improve using an optimal linear combination of the 4 variables over the rates produced by the single use of either the MMPI-A Depression content scale (A-DEP) or Scale 2. For the conduct disorder diagnosis, the optimal linear combination of MMPI-A Conduct Problems (A-CON), Cynicism (A-CYN), and Immaturity (IMM) scales served as the best predictor, and no Rorschach variables contributed significantly to classification accuracy. Our results replicated the findings of Archer and Gordon (1988) in indicating that the combined use of MMPI-A and Rorschach variables does not appear to produce incremental increases in accuracy of diagnostic classification.
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PMID:MMPI-A and Rorschach indices related to depression and conduct disorder: an evaluation of the incremental validity hypothesis. 950 82


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