Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Among 129 adolescent psychiatric inpatients, four subgroups of suicidal and/or assaultive behaviors were identified. A suicidal-only subgroup with no evidence of assaultive behavior was characterized by depression, drug abuse and environmental stresses. An assaultive-only subgroup with no evidence of suicidal behavior exhibited aggressive symptoms and violence at home. A subgroup with both suicidal and assaultive behaviors experienced accidents and family violence. A fourth subgroup had neither suicidal nor assaultive behavior. This subgroup showed eating disorders, depression, minimal assaultiveness and few peer friendships.
 ...
PMID:Subtypes of suicidal and assaultive behaviors in adolescent psychiatric inpatients: a research note. 292 20

Evidence of organic psychological deficits in Vietnam veterans exposed to the herbicide Agent Orange was established through a neuropsychological battery. Also, the exposed Vietnam veterans, in contrast to a matched control group of Vietnam veterans, showed a significantly higher rate of posttraumatic stress disorder and its associated features: depression, anxiety, and increased aggression. The latter was subdivided into uncontrollable pressures, verbal violence, violence against objects, assaults, and suicidal thoughts. Active cases of chloracne, a medical indicator, were used to determine Agent Orange exposure.
 ...
PMID:Agent Orange exposure and posttraumatic stress disorder. 296 15

Many adolescent affective disorders are rooted in biological vulnerability to stress and a predisposition to mood variations that are latent in childhood. As these stress-sensitive children encounter the normative helplessness and struggle for autonomy of adolescence, they may use violence, explosive rage, self-starvation, grandiose self-idealization, drug abuse, and suicidal behavior to relieve psychological helplessness and tension. They may begin a lifelong cycle of failure, disruption, and rejection by family and schools. The author describes adolescent depression and its biological underpinnings, deprivation syndromes, and manic-depressive illness, as well as the concept of affective violence in organic affective syndromes and episodic dyscontrol syndromes. These disorders call for multimodal treatment in which appropriate medication facilitates psychosocial intervention.
 ...
PMID:Affective disorders and violence in adolescents. 301 50

Although physical and sexual abuse are separate and distinct types of victimization, their impact on children is quite similar. Both of these forms of maltreatment involve the exploitation or misuse of a child by a parent or caretaker in the context of a pathologic family system. Physical and sexual abuse constitute an acute traumatic event for the child, generating phobic responses and anxiety-related symptoms including post-traumatic stress disorder. The long-term traumatic elements stemming from the chronic stigmatization and scapegoating contribute to problems of depression and low self-esteem and distortions in character formation. Betrayal by a primary caretaker leads to mistrust of others and difficulties with object relationships. Perhaps the most striking similarity between physical and sexual abuse of children is the tendency of the children to re-enact and recreate their victimization with others, leading to a transmission of violence in the next generation. Like their parents who were frequently victimized during childhood, they repeat and perpetuate an "aggressor-victim" interaction in their subsequent relationships. Both physical and sexual abuse are embedded in a deviant family structure, which adds to the psychopathology of the children. The contrast between physical and sexual abuse can be demonstrated by their specific impact on aggression and sexuality, respectively. The physically abused child has difficulty in experiencing and modulating aggressive impulses, whereas the victim of incest is often impaired in his ability to experience and integrate sexual feelings. The physically abused child is also at greater risk for cognitive and CNS impairment. Intervention with the abusing parents is the first step in protecting the children from further damage, but treatment of the child victims is necessary not only to diminish their psychopathology and emotional distress, but to prevent the cycle of violence in the next generation.
 ...
PMID:Child maltreatment and its victims. A comparison of physical and sexual abuse. 306 93

Three hundred eighty-three alcoholics, who had at least once been ordered supervision or compulsory treatment at an institution for alcoholics by the Temperance Board, were compared with 383 other alcoholics matched for age and sex. All the alcoholics were first admitted to the Department of Psychiatry, University Hospital, Lund, during the years 1949 to 1969 and followed up until January 1, 1981. They were systematically rated concerning symptoms and etiological factors at first admission. According to a stepwise logistic regression analysis, the following initial symptoms were positively associated with later compulsory treatment: slight cerebral dysfunction/personality change, antisociality/criminality, and impaired social and work performance. Social pressure/responsibility/conflict, slight depression, and continuous drinking were positively associated with the controls. There were 168 deaths in the compulsory treatment group and 124 in the control group (p less than 0.01). The excess deaths in the compulsory treatment group were mainly caused by accidents, poisoning, and violence (21 cases) and sudden cardiac death (10 cases), while there were no differences concerning alcohol-related neoplasms and liver cirrhosis. The compulsory treatment group had a worse long-term social adjustment. The findings indicate that compulsory treatment was related to behavioral patterns showing a stability over time, supporting the validity of subclassification of alcoholics using social data.
 ...
PMID:Alcoholics committed to treatment: a prospective long-term study of behavioral characteristics, mortality, and social adjustment. 327 54

This paper reviews the literature on childhood sexual abuse and its implications for women. It is estimated that at least 15-38% of adults have been sexually abused as children, with figures higher for women than for men. Failure to report abuse is common, and only 20-50% of incidents may come to the attention of authorities. Although childhood sexual abuse is present in all socioeconomic groups, more severe forms of abuse appear to be associated with lower socioeconomic status. After the age of ten, a sharp increase is observed in vaginal intercourse, sexual assaults accompanied by physical violence, and abuse committed by strangers. Although fathers are frequently cited as the primary perpetrators, not all studies support this finding. Other relatives have been reported to account for 20-70% of the sexual abuse occurring within the family. A history of childhood abuse may contribute to sexual problems or multiple chronic complaints in the adult woman. Moreover, some of these women may experience depression, anxiety, and low self-esteem. The gynecologist should use empathetic questioning with all patients regarding abuse, and integrate the patient's history of abuse with current health care. Physicians who are uncomfortable with this topic or who observe ongoing distress in their patients should refer these women to a mental health practitioner who is familiar with the issues common to women who have experienced childhood sexual abuse.
 ...
PMID:Childhood sexual abuse and the consequences in adult women. 328 Oct 78

Twenty-eight Turkish refugees living in Denmark were examined by the authors in the period 1984-85. Fourteen of the persons alleged having been tortured in Turkey during the period 1980-83. The remaining 14 persons reported that they had not been tortured and thus acted as controls. All the testimonies were found valid according to a method previously used by us. The most common forms of violence reported were blows and electrical torture. Blindfolding, solitary confinement and threats were also frequent. At the time of examination the main mental complaints were sleep disturbances with nightmares and impaired memory. Emotional lability and concentration disturbances were also frequent. Physically the torture victims suffered from headache, various cardio-pulmonary and muscular pains, dyspepsia and reading disturbances. All reported that they had been healthy before torture. The clinical examination revealed only a few signs related to torture, although examples of minimal scars, fractured or missing teeth, discrete neurological disorders and mental depression were found. The 14 controls had significantly fewer complaints, and almost no abnormalities were found during the clinical examination. The present study clearly demonstrates the traumatic effects of torture.
 ...
PMID:Sequelae to torture. A controlled study of torture victims living in exile. 333 88

Abused and nonabused child witnesses to parental violence temporarily residing in a battered women's shelter were compared to children from a similar economic background on measures of self-esteem, anxiety, depression, and behavior problems, using mothers' and self-reports. Results indicated significantly more distress in the abused-witness children than in the comparison group, with nonabused witness children's scores falling between the two. Age of child and types of violence were mediating factors. Implications of the findings are discussed.
 ...
PMID:Psychological and behavioral correlates of family violence in child witnesses and victims. 334 3

The literature on the current health problems of women is reviewed, clarifying the conditions and updating present knowledge of women's health within the context of medical and social research. Both medical professionals and women have begun to address women's health issues with 4 major issues receiving particular emphasis: the charge that physicians fail to take women's complaints seriously; the allegation that the population of women is being drugged; the accusation that women experience excessive surgical procedures; and the notion that sexism is inherent in American medical education. Focus on these issues is not the answer. Women, individually and collectively, need to clarify issues of women's health within the context of modern research and understanding. The literature is reviewed in the categories of prepubescent females, adolescence and the young woman, women's reproductive lives, life styles of the middle years, external and internal abuse, and aged women. The estimated annual occurrence of 60,000-100,000 cases of incest and/or sexual abuse among prepubescent females makes it a women's health issue of serious dimension. The victims are overwhelmingly female with a ratio of 10 females to 1 male child. Appetite disorders, known as patharexia, are a major public health problem of female adolescents. After depression, they represent the most common emotional illness among young girls and women. Anorexia nervosa, bulimarexia, and bulimia all are characterized by body image and distortion and the victim's obsessive desire to be thin. A more conforming, but still inappropriately adapted, response to social expectations for women is teen pregnancy. Teenagers who decide to have their babies often are those with the fewest options. Voluntary childlessness, late age childbirth, and issues of reproductive freedom are having social, political, and economic impact on the lives of all women. The prevailing social context of sexism and inequality contributes to the origin and persistence of problems of women patients, as demonstrated by the correlation between subordinate group status and mental health. Many changes have been initiated as a result of pressure from individual women and from the women's health care movement. For example, medical schools are reforming their training in values, ethics, and human relations. Women have begun to assume more control over their own lives and well being. Women's groups such as the Boston Women's Health Collective have set the pattern for a proliferation of self-help manuals available to the general readership. Recent media attention has focused on such women's health issues as family violence, incest, and battering. Women have challenged the medical professionals in their treatments, and medical professionals need to see beyond individual symptoms to the context of illness in women. Complete health for women can be a new model for other social movements.
 ...
PMID:Women's health from a woman's point of view: a review of the literature. 352 18

This clinical presentation deals with the aftereffects, in a male patient, of a severely disturbed rapprochement phase, marked by many separations and a molestation before the age of three. The patient dreamed repeatedly of violence, often directed against himself, but the actual molestation was sealed off by formidable repression. A first analysis, with a male analyst, produced no relief from the patient's depression, crippling insomnia, and inability to form an intimate relationship. The second analysis progressed only when the repetitive dreams were understood to be repressed experiences of seduction and molestation.
 ...
PMID:Reconstruction of an early seduction and its aftereffects. 358 15


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>