Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011570 (
depression
)
172,036
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Background:
Fatigue is one of the most common and disabling symptoms of
sarcoidosis
. The cause of fatigue remains unclear and is usually multifactorial. The majority of previous studies evaluated clinical parameters with only few of them including assessment of psychological factors as contributing to the severity of the symptoms.
Objective:
The aim of this study was to evaluate the relationship of emotional distress, physical concerns, and dyspnea in explaining fatigue in patients with
sarcoidosis
.
Methods:
Fifty-seven patients with
sarcoidosis
were enrolled to the study and filled out measures of fatigue (FAS), dyspnea (MRC), anxiety sensitivity (ASI-3), and anxiety and
depression
(HADS).
Results:
Linear regression revealed that distress and physical concerns subscale of ASI are significant predictors of fatigue explaining jointly 53.5% of fatigue variance.
Conclusions:
The results of the study emphasize the importance of including emotional distress and physical concerns into the diagnostic procedures and management of fatigue in
sarcoidosis
.
(
Sarcoidosis
Vasc Diffuse Lung Dis 2018; 35: 160-164)
.
Sarcoidosis
Vasc Diffuse Lung Dis 2018
PMID:Relationship of emotional distress and physical concerns with fatigue severity in sarcoidosis. 3247 97
Background:
Exercise training have been shown to be the effective approach for functional outcomes in interstitial lung diseases (ILD). In many studies, the duration of exercise programs (EPs) varies between 8-12 weeks. However, the optimal duration of EPs is still unknown.
Objective:
In our prospective non-controlled study, we aimed to compare the results of the 8
th
week with the results of the 12
th
week of the PR programs applied to the patients with ILD.
Methods:
A total of 14 patients [Age; 63(53,70) years, body mass index: 28(25,32) kg/m
2
, disease duration; 1.5 (1,4) years] with ILD [11 idiopathic pulmonary fibrosis, 2
sarcoidosis
(stage 3 and 4) and 1 nonspecific interstitial pneumonia] were included in the study. 6-minute walk test, pulmonary function test, arterial blood gas analysis, mMRC dyspnea scale, quality of life questionnaires and hospital anxiety depression scale were performed at before and 8 and 12 weeks after the program.
Results:
6-minute walk distance, dyspnea, anxiety,
depression
and quality of life improved both at 8
th
and 12
th
week after EP when compared the with the initial assessment(
P
<0.05). When compared with 8
th
week; mMRC dyspnea score, 6-minute walk distance and quality of life scores significantly improved at 12
th
weeks (
P
=0.046,
P
=0.016,
P
<0.05, respectively).
Conclusions:
Prolonging duration of the EPs results in more improvement in functional outcomes in patients with ILD. However, it has no effect on pulmonary functions and arterial blood gas results.
(
Sarcoidosis
Vasc Diffuse Lung Dis 2018; 35: 299-307)
.
Sarcoidosis
Vasc Diffuse Lung Dis 2018
PMID:A comparison trial of eight weeks versus twelve weeks of exercise program in interstitial lung diseases. 3247 17
A 58-year-old woman experienced 4 months of headache, fatigue, and
depression
, as well as 1 week of confusion and hallucinations. F-FDG PET/CT showed numerous hypermetabolic lesions in the pituitary gland and stalk, dura mater, glossopharyngeal nerve, and cauda equina, as well as in cervical and mediastinal lymph nodes. Surgical biopsy of the mediastinal lymph node confirmed the diagnosis of
sarcoidosis
. The follow-up F-FDG PET/CT, performed at the eighth month after the treatment of glucocorticoids and immunosuppressive agents, demonstrated complete remission of the previous hypermetabolic lesions.
...
PMID:18F-FDG PET/CT Findings in a Patient With Neurosarcoidosis. 3252 Apr 95
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