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 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We investigated the role of genitourinary tract infections, structural and psychologic abnormalities in 75 men referred to a "chronic prostatitis" clinic. Patients had had symptoms for an average of eighty-three months and had received an average of ten weeks of antimicrobial treatment during the three months prior to evaluation. Specific infectious diseases, structural or functional causes were identified in 34 (45%) of the 75 patients. Genitourinary tract pathogens were isolated from 26 patients and inflammation was documented in urethral or prostatic secretions of 24 patients. Structural or functional abnormalities that merited treatment were identified in 8 cases. In addition, major criteria for depression were documented in 9 of 17 patients who agreed to this evaluation. Overall, a comprehensive approach to diagnosis led to specific treatment for 37 (49%) of the 75 men with chronic prostatitis, despite longstanding symptoms and failure of multiple prior courses of therapy.
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PMID:Comprehensive evaluation and treatment of 75 men referred to chronic prostatitis clinic. 186 51

Personality testing was performed on 56 patients with clinical symptoms of chronic prostatitis. The psychological methods used were RO, TAT, FAM and Beck's Depression Inventory. Q factor analysis of the patients was performed and yielded four factors representing four different personality pathologies, i.e. psychosomatic structure, alexithymic personality, borderline personality and narcissistic personality. The duration of the somatic symptoms correlated positively with the severity of the psychic symptoms. The etiology of the different pathologies expressed by the patients with chronic prostatitis was, according to the researchers, the same. All are disorders of the pregenital level and all can be interpreted as a consequence of disturbance of the first object relationships, the key factor being defective fantasy development.
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PMID:Personality pathology underlying chronic prostatitis. 712 91

A psychological study, which included personality testing (BDI, MMPI, RO, TAT), was performed on 42 patients with clinical symptoms of chronic prostatitis. The patients were characterized by prolonged symptoms and poor response to treatment by general practitioners. Some degree of psychic difficulty was revealed in 80% of the patients, and signs of severe psychic disturbance in 20 to 50%. The outstanding psychic symptoms were anxiety, depression, affect-lability, weak masculine identity and other sexual disorders, and even psychotic features. This pattern of psychic disorders corresponds with that described for borderline personality. The common occurrence of specific psychic and sexual disturbances suggests that these psychic factors may have a causative role in chronic prostatitis.
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PMID:Psychic disturbances in patients with chronic prostatis. 719 83

Psychologic factors have been considered to play an important role in the etiology of chronic prostatitis. Earlier studies are often based on a psychoanalytical perspective and seldomly used quantitative approaches. In the present study quantitative tests are used to investigate personality variables which are suggested in the literature as underlying chronic prostatitis. A group of 50 chronic prostatitis patients was compared with a group of 50 patients seen for a vasectomy. Psychologic measures were taken by means of a personality inventory (NVM, Dutch short form of the MMPI), a symptom checklist (SLC-90), and a depression inventory (IDD). Results showed statistically significant differences between the groups, with the chronic prostatitis patients scoring consistently higher on the measures than vasectomy patients. However, these differences in scores were not of a great magnitude and minor compared with differences in scores from psychiatric patients. Discriminant analysis suggested somatization and depression to be the key variables to distinguish chronic prostatitis patients from vasectomy patients. Overall, it seemed unfounded to label chronic prostatitis patients "neurotic" or "psychopathologic," and it was impossible to conclude that there are personality variables that specifically identify the chronic prostatitis patients.
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PMID:Personality variables involved in chronic prostatitis. 825 99

Idiopathic prostatitis is a common, often chronic condition in which psychological factors are suspected to play a role. Men with chronic prostatitis (n = 51) and a control group of 34 men without any chronic pain condition, equivalent on demographic characteristics, were compared on psychological and perineal muscle tension measures. Prostate-specific antigen and expressed prostatic secretion cell counts were also measured. Chronic prostatitis patients were consistently more elevated than controls on hypochondriasis, depression, and hysteria (MMPI), and on somaticization and depression (Brief Symptom Inventory), and were less elevated on masculine/instrumentality (Personal Attributes Questionnaire) scales. A cluster analysis of MMPI profiles revealed that 57% of the chronic prostatitis patients produced generally unelevated MMPI profiles, whereas the remaining 43% fell into two groups with distinct patterns of distress. The results indicate depression and psychosocial distress are common among chronic prostatitis patients, calling for careful evaluation and attention to psychological symptoms.
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PMID:Psychological and physical factors involved in chronic idiopathic prostatitis. 897 61

Epidemiologic data have demonstrated the significance of chronic prostatitis/chronic pelvic pain syndrome (CP/CPSS) for the urological practice. Apart from the rare cases of bacterial prostatitis numerous somatic models have failed to completely explain pathogenetic interrelations; therapeutic attempts frequently have produced unsatisfactory results. Additionally, psychosomatic factors have often been neglected. A number of personality variables have turned out to play an important role in questionnaire-based studies, namely somatization and depression, as well as anxiety, hypochondriasis, and weak masculine identity. However, these preliminary results need further evaluation. In the future, diagnostic and therapeutic strategies should pay attention to the complex interweavement of somatic and psychogenic factors in the pathogenesis of CP/CPSS.
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PMID:[Psychosomatic aspects of the chronic pelvic pain syndrome]. 1504 82

A prospective multi-center Italian urology outpatient survey, undertaken to determine the prevalence of prostatitis in Italy, provided an ideal opportunity to identify and characterize the typical prostatitis patient presenting to Italian urologists. A total of 70 urologists, representing a cross section of urologic centers in Italy, counted and recorded the overall total male patients reported in the clinic and the overall total patients diagnosed with prostatitis over a 5 week period in late 2001. Data on demographics, previous diagnoses, symptoms (frequency and severity), quality of life, physical examination and laboratory data were prospectively collected. A total of 1,148 patients were identified with prostatitis (12.8%). Of these, 1,074 patients had complete data and could be included in this characterization analysis. The mean age of the prostatitis patients was 47.1 years (range 16-83); two thirds had experienced their first symptom within the last year. A family history of prostatitis was reported by 20.4%. The most common urinary diseases were benign prostatic hyperplasia (17.4%), recurrent urinary tract infection (11.2%) and urinary calculogenesis (11.1%), while the most common concurrent diseases were diabetes (7.2%) and depression (6.8%). The most frequently reported and most severe symptoms at the time of evaluation were irritative voiding symptoms, perineal and suprapubic pain and discomfort. Over three quarters of the patients were dissatisfied with their quality of life. Bacteria were cultured in 15.6%, 17.7% and 14.0% of expressed prostatic secretions, urine specimens after prostatic massage and semen specimens, respectively. Prostatitis is a common outpatient diagnosis, comprising over 10% of male outpatient visits to urologists in Italy. This comprehensive characterization of the typical prostatitis patient diagnosed in routine urological outpatient practice can be employed to generate hypothesis-driven studies in diagnosis and treatment.
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PMID:Clinical characterization of the prostatitis patient in Italy: a prospective urology outpatient study. 1577 May 19

The article presents the basic principles of cognitive-behavioural therapy and its applications in treating depression, anxiety disorders, post-traumatic stress disorder (PTSD) and addictions. The possibility of using cognitive-behavioural interventions for chronic somatic diseases (ischaemic heart disease, skin diseases, insomnia, migraine and chronic prostatitis) are also suggested.
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PMID:[The present application and the perspective progress of cognitive-behavioural therapy]. 1703 3

In recent years, more and more attention has been drawn to the role of phosphodiesterase 5 (PDE5) in penile erection. The cyclic nucleotide (cGMP) signaling pathway mediates the smooth-muscle relaxing effect of nitric oxide necessary for normal erectile function. Down-regulation of this pathway is the pathological pivot of many forms of erectile dysfunction (ED) and leads to the development of some chronic diseases. Therapeutic outcomes have shown that vardenafil is effective and safe in the treatment of ED associated with dyslipidemia, hypertension, depression, diabetes, radical retropubic prostatectomy, spinal cord injury, sildenafil failure, renal transplantation, chronic prostatitis and that accompanied by premature ejaculation. Vardenafil provides a reasonable therapeutic alternative for these refractory ED patients. In addition, vardenafil can prolong erectile duration of ED patients.
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PMID:[Vardenafil for refractory erectile dysfunction: the latest advances]. 2021 19

The study of changes in the immune status of patients with chronic bacterial prostatitis demonstrated changes in immunological parameters reflecting depression of the immune system (subnormal levels of interferon alpha, gamma, sIgA, functional activity of neutrophils, high concentration of IgA, IgG, IgM). Thus, combined treatment of chronic bacterial prostatitis must include administration of immunomodulators.
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PMID:[Clinical immunological rationale of interferon therapy in chronic bacterial prostatitis]. 2088 29


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