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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper reports a replication study of prediction of outcome by a cluster-analysis derived four-group typoloy of depression. 143 acutely depressed women were treated with amitriptyline for 4 weeks. In replication of the earlier findings, anxious depressives showed the worst response, hostile depressives and young depressive with personality disorder the best, with psychotic depressive intermediate. The findings provide further validating evidence for the typology, and for the view that nonpsychotic depressives are heterogenous.
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PMID:Typological prediction of response to amitriptyline: a replication study. 33 87

Patients suffering from character disorder are often rejected as unsuitable for psychotherapy. Those with anxiety and depression often seek help, and should be assessed for their potential to be helped by a carefully structured long term psychotherapeutic relationship controlled by the therapist to reduce acting out behaviour. The therapist acts throughout as a model for the patient. As the patient develops basic trust in the therapist, identification develops and a major sustained improvement can occur. The therapy described is current-behaviour orientated and the importance of clear, unambiguous communication, particularly verbal communications, is stressed. The principles of therapy are applicable to all contacts with character-disordered patients. Briefly described is the long term therapy of two patients with hysterical personality disorders and acting-out behaviour, as examples of one type of the wide variety of character disorders that can be treated, and where the nine year follow up was adequate to ensure that improvement was sustained.
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PMID:The psychotherapy of character disorder. 41 69

The classification of depression remains controversial (Kendell, 1976). Overall et al. (1966) used the Brief Psychiatric Rating Scale (PBRS), a computer classification procedure and derived three depressed groups: anxious, hostile and retarded depressives. Paykel (1971, 1972) reported four groups derived from a multivariate cluster analysis: psychotic depressives and '...three groups, anxious, hostile and young depressives with personality disorder, from the diversity of patients subsumed under neurotic depression'. Amongst 85 women treated with amitriptyline 'this typology predicted outcome significantly'. This paper presents the results of a cluster analysis of a group of 60 female out-patient neurotic depressives.
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PMID:Are there different types of neurotic depression? 48 55

To devise a system of classifying depression subtypes at intake, the authors administered the Kupfer Detre Scale (KDS-3A) to depressed outpatients at intake and after one, three, and six months of treatment with tricyclic antidepressants or lithium carbonate. None of the 10 tricyclic responders scored below 8 on the 14-point chronic anxiety scale at intake while 7 of the 12 lithium responders did, suggesting that any patient scoring below 8 is a probable candidate for lithium therapy. Patients scoring 8 or above on the chronic anxiety scale fell into two categories, those who had a low impulisivity score and responded to tricyclic antidepressants and those who had a high impulsivity score, responded to lithium, and had cyclothymic disorder or emotionally unstable character disorder.
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PMID:Subtypes of depression identified by the KDS-3A: a pilot study. 49 93

Used a measure of reduction in experienced control to investigate two aspects of the learned helplessness model of depression. Consistent with this model, psychiatric inpatients who reported reduced control over life events prior to hospitalization were significantly more depressed than individuals who reported no such reductions. Locus of control (IE) was not related to depression scores, and it was suggested, in light of previous research, that future research on the antecedents of depression employ more specific measures of control rather than measures of generalized expectancies. Additionally, depressive as a diagnostic group reported greated reduced control than chronic schizophrenics, paranoid schizophrenics, and patients with personality disorder diagnoses. These results were interpreted as supporting the specificity of learned helplessness to depression. It was suggested that research on learned helplessness and depression, which has relied on college student analogues, can be complemented profitably by studies of reduced experience control within clinical populations.
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PMID:Reductions in experienced control and depression in psychiatric inpatients: a test of the learned helplessness model. 69 Jan 95

Combined monoamine oxidase (MAO) inhibitor-tricyclic antidepressant therapy and electroconvulsive therapy (ECT) were compared in a population of refractory depressive patients. Seventeen patients were randomly assigned to either of the treatment groups, and an independent observer was used to rate overall progress. Between four and ten ECTs or a combination of phenelzine and amitriptyline were administered. Assays for MAO activity and plasma levels of amitriptyline and nortriptyline were performed. In both psychotic and neurotic depression, ECT was superior. When depression was accompanied by character disorder, the response was generally poor. Adequate levels of MAO inhibition were obtained, but tricyclic antidepressant levels were low. Electroconvulsive therapy is still considered to be the treatment of choice for severe depression, whereas the combination of low doses of phenelzine and amitriptyline are ineffective. This treatment modality needs further investigation.
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PMID:A comparison of electroconvulsive therapy and combined phenelzine-amitriptyline in refractory depression. 72 3

Somatic disorders in depression can be separated into two main categories. The first comprises those which are true side effets of drug-therapy; the other includes somatic symptoms of the depression itself, which are subsequently considered as apparent side effects. Under the same treatment true side effects occur much more frequently in psychogenic depression, especially if the patient has a personality disorder. During the course of the treatment the disappearance of somatic complaints is noticed more easily by the physicians than the appearance of true side effects (schulterbrandt). The relative frequency of symptoms of depression as compared with all other symptoms seems to be higher in manic-depressive psychoses than in other varieties of depression (Watts). The other somatic disorders might either be symptoms of organic illness with secondary depression, the psycho-somatic equivalents of depression, or finaly the only symptoms of a masked depression.
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PMID:[Somatic disorders and depressive states]. 75 93

The purposes of the present study of chronic pain patients were to (a) assess whether cognitive and behavioral coping style is related to personality factors, (b) assess how coping styles differ across personality types, and (c) assess how outpatient interdisciplinary intervention affects the coping styles of various personality types. Four MMPI clusters (Depression/Pathological, V-type, Marginal Depression, and Marginal V-type) were derived using a hierarchical clustering procedure. Seventy subjects also completed the Coping Strategies Questionnaire before and after a 3-week outpatient pain management program. Pretreatment analyses indicated the Depression/Pathological and Marginal Depression groups used diverting attention less than either V-type group. The V-type group reported using praying/hoping significantly more than either of the marginal groups. At posttreatment the Depression/Pathological group used catastrophizing significantly more than either of the marginal groups. Results of pre-post analyses indicated that the Depression/Pathological group increased their use of diverting attention, reinterpreting pain sensations, and ignoring pain sensations, while decreasing catastrophizing. The V-type group increased their use of reinterpreting pain sensations, while decreasing praying/hoping and catastrophizing. Neither of the Marginal subtypes showed significant pre-post changes in coping strategies. These results suggest that different personality types use different pain coping strategies prior to multidisciplinary treatment. Groups showing more severe psychological distress, perhaps related to an underlying personality disorder, displayed greater changes in coping strategies with treatment, but remained more dysfunctional after treatment. These findings suggest that the alteration of coping strategies may be an important treatment effect needing more individualization to maximize treatment response.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Relationship of MMPI cluster type, pain coping strategy, and treatment outcome. 138 94

In the last decade, a great deal of research has been accomplished in the study of borderline personality, but the literature is yet to systematically examine the intimate relationships of individuals with this particular personality disorder. In doing so, this study compared a sample of female borderlines with an adequately matched sample of non-personality disorders (aged 23-33 years) using the following measures: the Hurlbert Index of Sexual Assertiveness, the Sexual Opinion Survey, the Sexuality Scale, and the Index of Sexual Satisfaction. In the borderline sample, about 50% of the women reported a childhood history of physical or sexual abuse, as compared to about 15% in the control group. Also, borderline women were found to have significantly higher sexual assertiveness, greater erotophilic attitudes, and higher sexual esteem. Despite these findings, the borderline group evidenced significantly greater sexual preoccupation, sexual depression, and sexual dissatisfaction. Implications for these findings and treatment issues are discussed.
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PMID:An empirical examination into the sexuality of women with borderline personality disorder. 140 44

The total number of adults with Down's syndrome living in Leicestershire, ascertained by widespread enquiry, was found to be 378. Of these, 371 were matched with adults with mental handicap due to other pathologies, on the basis of age, sex, and type of residence. Those with Down's syndrome were found to have a different spectrum of mental disorders from those without the syndrome. In particular, Down's syndrome patients were more likely to have been diagnosed as having depression and dementia; the controls were more likely to have been diagnosed as suffering from conduct disorder, personality disorder, or schizophrenia/paranoid state. The same proportion of each group had been given a diagnosis of autism.
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PMID:Differential rates of psychiatric disorders in adults with Down's syndrome compared with other mentally handicapped adults. 833 Jan 25


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