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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty-three consecutive admissions to a psychodynamically oriented day treatment program were assessed using a pre-/post-test design. Discharge scores revealed a significant improvement on all standardized scales for behaviour (p less than .0001), academics (p less than .05), personality measures (p less than .0001) and family measures (p less than .05). Parents reported a significantly greater behavioural improvement than both teachers and primary therapists (p less than .0001). Although all children showed improvement, parents reported significantly lower improvement rates (p less than 0.05) for children with conduct disorder compared with attention deficit disorder, oppositional defiant disorder and depression. Teachers found that younger boys (aged six to nine) showed a significantly greater improvement (p less than .05) than older boys (aged ten to 12) in total behaviour score and externalizing subscores of the Revised Child Behavior Profile. At discharge 87% of children were reintegrated into regular school; only 17% were attending regular school at admission.
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PMID:Evaluation of the effectiveness of a psychodynamically oriented day treatment program for children with behaviour problems: a pilot study. 220 86

To assess relationships of total plasma cholesterol (TC) and triglyceride (TG) values to suicide, suicide ideation, and hospitalization for psychiatric disease, we studied 220 children, ages 5 to 18 y, hospitalized with affective, adjustment, disruptive, anxiety, schizophrenic, other, and organic psychiatric disorders. The 135 male and 85 female patients had higher TG values (p = 0.0001 and 0.0003, respectively) and higher Quetelet Indices (p = 0.0001 and 0.003, respectively) than the 732 male and 316 female schoolchild controls; male patients had higher TC values than male controls (p = 0.014). Substance abuse in patients was an independent inverse determinant of TC value (p = 0.05); TG value correlated positively with alcohol use (p < or = 0.1) and substance abuse (p < 0.05). After covariance adjustment for age, race, sex, and Quetelet, children having adjustment disorders with depression had much lower covariance-adjusted TC value than control schoolchildren (3.91 versus 4.29 mmol/L, p = 0.003), whereas those with disruptive behavior with oppositional defiant disorder had much higher adjusted TC value (5.09 mmol/L, p = 0.0001). After covariance adjusting for age, race, sex, Quetelet, cigarette smoking, alcohol use, and substance abuse, children having adjustment disorders with concomitant depression had the highest group suicide tendencies (attempts and ideation) and the lowest covariance-adjusted TC value (4.03 mmol/L). Conversely, children having disruptive behavior with attention deficit hyperactivity disorder or disruptive behavior with oppoistional defiant disorder had 50% lower suicide index than those with adjustment disorders with concomitant depression and higher adjusted TC levels (4.45 and 5.12 mmol/L, p = 0.0003).(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Hypocholesterolemia, hypertriglyceridemia, suicide, and suicide ideation in children hospitalized for psychiatric diseases. 806 45

Mental health disorders in adolescence are pervasive, often carry into adulthood, and appear to be inversely associated with social status. We examine how structural aspects of neighborhood context, specifically, socioeconomic stratification and racial/ethnic segregation, affect adolescent emotional well-being by shaping subjective perceptions of their neighborhoods. Using a community-based sample of 877 adolescents in Los Angeles County, we find that youth in low socioeconomic status (SES) neighborhoods perceive greater ambient hazards such as crime, violence, drug use, and graffiti than those in high SES neighborhoods. The perception of the neighborhood as dangerous, in turn, influences the mental health of adolescents: the more threatening the neighborhood, the more common the symptoms of depression, anxiety, oppositional defiant disorder, and conduct disorder. Social stability and, to a lesser extent, social cohesion, also emerge as contributors to adolescent disorder. This investigation demonstrates that research into the mental health of young people should consider the socioeconomic and demographic environments in which they live.
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PMID:The neighborhood context of adolescent mental health. 899 86

Reliability of the Dominic-R, a questionnaire combining visual and auditory stimuli, was tested in 340 community children aged 6 to 11 years. Test-retest reliability of symptoms of, and symptom scores of, DSM-III-R disorders including simple phobias, separation anxiety disorder, overanxious disorder, depression/dysthymia, attention deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder was assessed. Most symptoms yielded kappas greater than .40, and ICCs ranged from .74 to .81. In conclusion, reliability of the Dominic-R compares favourably with that of other child assessment questionnaires.
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PMID:Reliability of the Dominic-R: a young child mental health questionnaire combining visual and auditory stimuli. 931 81

The study consisted of evaluating 80 out-patients for DSM-IV diagnoses and giving 75 mg trazodone for four months to children aged 9-13 who fulfilled DSM-IV criteria for Major Depressive Disorder (n = 22); Major Depressive Disorder and Generalized Anxiety Disorder (n = 24), Major Depressive Disorder and Learning Disorder NOS (n = 24); Major Depressive Disorder and Oppositional Defiant Disorder (n = 10). They were followed up weekly by a psychiatrist blind to the original evaluations and to the precise purpose of the study. Trazodone emerges as safe and effective for over 50% of the sample. Those with depression alone and with LD NOS did particularly well, and those with ODD did particularly badly. The presence of psychopathology in the parents was associated with poorer response to trazodone, and life events were also associated with a poor response.
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PMID:Depressive disorder in pre-adolescence: comorbidity or different clinical subtypes? (A pharmacological contribution). 933 23

This summary of the practice parameters describes the diagnosis, treatment, and prevention of conduct disorder in children and adolescents. The rationales for these recommendations are based on a review of the scientific literature and clinical consensus, which are contained in the complete document. Clinical features of youths with conduct disorder include predominance in males, low socioeconomic status, and familial aggregation. Important continuities to oppositional defiant disorder and antisocial personality disorder have been documented. Extensive comorbidity, especially with other externalizing disorders, depression, and substance abuse, has been documented and has significance for prognosis. Clinically significant subtypes exist according to age of onset, overt or covert conduct problems, and levels of restraint exhibited under stress. To be effective, treatment must be multimodal, address multiple foci, and continue over extensive periods of time. Early treatment and prevention seem to be more effective than later intervention.
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PMID:Summary of the practice parameters for the assessment and treatment of children and adolescents with conduct disorder. 933 62

These practice parameters address the diagnosis, treatment, and prevention of conduct disorder in children and adolescents. Voluminous literature addresses the problem from a developmental, epidemiological, and criminological perspective. Properly designed treatment outcome studies of modern psychiatric modalities are rare. Ethnic issues are mentioned but not fully addressed from a clinical perspective. Clinical features of youth with conduct disorder include predominance in males, low socioeconomic status, and familial aggregation. Important continuities to oppositional defiant disorder and antisocial personality disorder have been documented. Extensive comorbidity, especially with other externalizing disorders, depression, and substance abuse, has been documented and has significance for prognosis. Clinically significant subtypes exist according to age of onset, overt or covert conduct problems, and levels of restraint exhibited under stress. To be effective, treatment must be multimodal, address multiple foci, and continue over extensive periods of time. Early treatment and prevention seem to be more effective than later intervention.
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PMID:Practice parameters for the assessment and treatment of children and adolescents with conduct disorder. American Academy of Child and Adolescent Psychiatry. 933 68

Levels of adult distress and ad lib alcohol consumption following interactions with child confederates were investigated in parents of children with no diagnosable psychiatric disorders. Sixty parents (20 married couples and 20 single mothers) interacted with boys trained to enact behaviors characteristic of either normal children or "deviant" children with externalizing behavior disorders--attention-deficit hyperactivity disorder (ADHD), conduct disorder (CD), and oppositional defiant disorder (ODD). Relative to the normal child role, interactions with deviant confederates were rated as significantly more unpleasant, resulted in feelings of role inadequacy, and produced significantly more anxiety, depression, and hostility. After the interactions, parents were given the opportunity to drink as much of their preferred alcoholic beverage as they desired while anticipating a second interaction with the same child. The participants consumed more alcohol following exposure to deviant as opposed to normal confederates.
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PMID:Effects of deviant child behavior on parental distress and alcohol consumption in laboratory interactions. 942 49

A 5-year-old boy presented with attention deficit hyperactivity disorder (ADHD), oppositional defiant disorder and separation anxiety disorder. The clinical assessment revealed longstanding parent-child relationship problems, ongoing family stress, and a chronic level of low grade depression in the mother. The treatment approach consisted of drug treatment of the child and long-term psychotherapy of the mother. At termination symptoms associated with ADHD were markedly reduced and parent-child relationship problems were no longer evident. It is argued that in a subgroup of children family stress and attachment difficulties may be involved in the development of ADHD. These difficulties should be considered separately in the treatment of children with ADHD, especially if still present after the symptomatic treatment. The treatment outcome raises the question whether or not certain symptoms attributed to ADHD may be reversible, and the long-term adverse outcome of the condition preventable.
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PMID:The synergistic effects of stimulants and parental psychotherapy in the treatment of attention deficit hyperactivity disorder. 972 86

We applied a computationally practical form of probit analysis for multiple response variables to data on early childhood development of four psychiatric disorders: disruptive disorders (DD-attention deficit disorders, oppositional defiant disorder, conduct disorder); adjustment disorders (ADJ); emotional disorders (ED-all anxiety disorders, depression); and other DSM-III-R Axis I disorders (OTHER). In addition to estimating the intercept slope and higher order polynomial terms for each age versus diagnosis regression, we estimated simultaneously the correlation among the four diagnostic categories. We then took into account the correlation found among these four diagnostic categories when testing the hypothesis of no age effect, which would have been ignored in a piecemeal univariate approach. Regression lines for diagnostic prevalence indicate a linear increase for OTHER disorders, and a curvilinear increase for ED. We then used expected frequencies of individual response patterns (that is, the 2(4) = 16 possible diagnostic combinations) in obtaining more precise estimates of diagnostic comorbidity and its relation to age. We further generalize the Bock and Gibbons model to alternative specification of the random-effects distribution (that is, they assumed multivariate normality), illustrate how one can estimate the random-effects distribution empirically, and study the robustness of parameter estimates to specification of the random-effects distribution.
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PMID:Emergence of childhood psychiatric disorders: a multivariate probit analysis. 981 40


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