Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In 555 stress-induced urinary incontinent and 119 continent women patients, we studied the history, clinical and urodynamic investigations to define the hypotonic urethra and to find out important etiological factors of the low urethral closure pressure. The linear depression of the urethral pressure and the urethral closure pressure at rest--well known from literature--has been confirmed in this study. With hypotonic urethra, closure pressure values were found to be below the simple standard deviation from a norm-curve. Also, in cases of stress urinary incontinence, we found a nearly linear depression of closure pressure. The stress incontinent patients could be divided in two groups: 46% with hypotonic urethra, 54% with nearly normal closure pressure. History of former incontinence surgery, but also of other operations such as simple abdominal or vaginal hysterectomy, is correlated with low urethral closure pressure. The degree of closure pressure is correlated with shortening of the functional urethral length. The maximum closure pressure shifts distally. Women, who, despite hypotonic urethras, are continent, build up a positive closure pressure throughout a broad zone of the functional urethral length. Contrarily, in the case of incontinent patients, even a weak coughing spasm, which does not even break through the bladder sphincter in maximum closure, can cause opening of the urethra and establishment of pressure equilibration between bladder and urethra.
 ...
PMID:[Definition and etiologic factors of hypotonic urethra in relation to urinary stress incontinence in the female]. 258 28

A comprehensive evaluation of incontinence using office-based techniques may discover reversible problems such as delirium, urinary infections, vaginitis, depression, drug effects, endocrinologic causes, immobility, or impaction. Treatment of these causes may alleviate incontinence. Bedside urodynamics are a sensitive, specific, and useful office-based technique that can identify detrusor instability, overflow incontinence, or stress incontinence. Low urinary flow rate, difficulty with catheterization, slow bladder filling or severe urgency, bladder capacity over 600 ml, and post-void residual over 150 ml need referral. Patients with hematuria, recurrent infections, recent surgery or pelvic irradiation, and pelvic or prostatic masses also need further evaluation. A number of medical and behavioral therapies are available for stress incontinence and detrusor instability that can substantially reduce incontinence, but most patients with overflow have more complicated problems requiring further evaluation, surgery, or long-term bladder drainage.
 ...
PMID:Practical management of urinary incontinence. 268 69

Our first 23 patients treated by this method were followed up by urodynamic assessment and urethrocystovaginography 13 months after the operation. Urodynamic assessment was performed according to the criteria of the International Continence Society. There was no statistically significant difference in the resting urethral closure pressure (UCP), neither at maximum point nor at 30% or 70% of the urethral functional length (UFL). The postoperative reduction of UFL was statistically significant but did not exercise any significant influence on continence. The maximum bladder volume was not affected. For assessing the urethral stress profile we calculated the depression quotient which was significantly unfavourable at 30% of UFL but not affected at 70%. The lateral urethrocystovaginogram was interpreted according to Green. Most of the parameters were significantly improved. At the time of reexamination 70% of the patients were subjectively continent, whereas in 21.7% the incontinence remained unchanged and deteriorated in 8.6%. In our opinion, this modified anterior repair is not recommended as a method to encourage a wider range of indications for the vaginal repair of incontinence. Hence, this operation method should be performed only in case of an evident insufficiency of the vesicourethrovaginal septum.
 ...
PMID:[Urodynamic and roentgenologic changes following ventral levatorplasty]. 304 90

To select topics for quality assurance activities focusing on older patients, we convened a 14-member panel of physicians and experts in quality assurance. In two rounds of ratings, panelists rated 42 medical conditions (eg, pneumonia) in terms of their effects on patient outcomes, the availability of beneficial interventions, and the health benefits from improving current quality. They rated 27 health services (eg, adult day-care) on similar dimensions. The feasibility of doing quality assurance work on each condition and service also was rated. Using the ratings, the conditions selected for quality assurance work were congestive heart failure, hypertension, pneumonia, breast cancer, adverse effects of drugs, incontinence, and depression. Health care services selected were hospital discharge planning, acute inpatient care for the frail elderly, long-term-care facilities (intermediate-care facilities and skilled nursing facilities), home health care services, and case management.
 ...
PMID:Assuring the quality of health care for older persons. An expert panel's priorities. 365

Urodynamic tests and clinical and anamnestic assessments of continence were carried out in 47 patients before and after the Marshall-Marchetti-Krantz operation. The operation resulted in a subjective cure in 35 (74.5%) of the patients; 12 women were again incontinent within a period of between 6 and 24 months. There was an insignificant postoperative rise in urethral occlusion pressure at rest. It was only possible to ensure an elongation of the urethra in the resting pressure curve. The urethral occlusion pressure at rest in patients with recurrent incontinence was considerably lower preoperatively than in postoperatively continent patients. Hence, high urethral occlusion pressure at rest signifies a good surgical prognosis. In the stress pressure curve, surgery improved the transmission factor, the depression factor, and the urethral occlusion pressure under stress. However, no clear surgical prognosis was possible on the basis of these parameters. The best postoperative results for the transmission and depression factors and the urethral occlusion pressure under stress were obtained in the stress pressure curve at 300 ml with the patient in seated position. On comparing preoperative and postoperative measurements, improvements in pressure transmission and in urethral occlusion pressure under stress were seen in particular in the proximal one-third of the urethra. Hence, the question arises whether the proximal one-third of the urethra is as important as the medial one-third in stress incontinence diagnosis by measurement.
 ...
PMID:[Urodynamic observations on the Marshall-Marchetti-Krantz operation]. 377 Apr 15

The clinical presentation of three patients with meningiomas at different frontal sites is described. They had been ill for 3, 25, and 43 years before the tumour was demonstrated radiologically. Apathy, incontinence, dementia, and fits were seen in association with middle and superior frontal lesions, and may be mistaken for symptoms of involutional depression or presenile cerebral atrophy. In contrast, excitement and hallucinosis were seen in association with a basal frontal lesion, and may mimic psychotic syndromes like hypomania and schizophrenia, particularly if the tumour encroaches on the third ventricle and adjacent structures. Irreversible loss of myelin and axons in the frontal areas of brain surrounding the tumour may have contributed to the clinical picture of the syndrome shown by these patients.
 ...
PMID:Three cases of frontal meningiomas presenting psychiatrically. 496 22

Examination of 163 nursing home residents revealed chronic brain syndrome of different amount in 84%. Demented patients with clinical evidence of arteriosclerosis had significantly higher values of emotional incontinence, dysphoria, depression and vegetative complaints than those without evidence of arteriosclerosis. Correlation of single psychopathologic parameters with other psychopathologic, neurologic and somatic variables resulted in very different correlation profiles for the following symptoms: emotional incontinence, apathy, dysphoria and euphoria. These changes in personality should be considered to a higher degree in dementia research intending more homogeneous subgroups.
 ...
PMID:[Psychopathology of senile dementias in nursing home residents]. 647 86

The mental state, demographic details, dependency level and presence of problem behaviours have been recorded for 438 (82%) of the residents of the 12 Part III homes, managed by the London Borough of Camden, using standard interview. One third of the residents were suffering from severe dementia, another third from mild to moderate dementia and one third were free of dementia. Of the latter two groups, 38% were depressed. The prevalence rate of dementia increased with the age of the resident and was higher among females. Depression was associated with the presence of visual handicap and incontinence, and was commoner when the resident had been admitted from his own home or belonged to a minority religion. A third of residents needed daily help with dressing and use of the lavatory, one quarter were incontinent each day. Depression and dementia both were associated with increased rates of dependency and of problem behaviours (incontinence, wandering, aggression). This survey has revealed evidence of sufficient psychiatric morbidity in these homes to support a re-appraisal of their current aims, staffing and health-care provision.
 ...
PMID:Psychiatric illness in residential homes for the elderly: a survey in one London borough. 649 36

The perfusion urethrotonometry was used in this study in 34 patients both in lying and upright position as paired comparisons. The following problems could be solved: 1. Using the complex urodynamic unit of the authors examinations are possible in vertical position successfully. 2. The urethral pressure profiles are equivalent qualitatively in both examination positions. 3. The analysis of the profiles of both positions on principles demonstrates the same valuation. In case of incontinence the relevant parameters for diagnosis (functional length of urethra in stress profile, electronically registered urethral closure pressure in stressful situation, transmission and depression factor and stress quotient) show clearer in the upright position than in the lying one. In continent women the change of position has no significant influence. If the criteria in lying position are not well defined, the urethral pressure profile in upright position should be done as additional examination.
 ...
PMID:[New aspects of the Heidenreich and Beck perfusion method in urodynamics. II: Effect of examination position on parameters of urethral pressure profile]. 668 74

The quality of life for patients with carcinoma of the lower two-thirds of the rectum (5-12 cm from the anal verge) treated by abdominoperineal resection (APER, n = 38) was compared with that of a similar group of patients treated by low sphincter saving resection (SSR, n = 40). Assessment was by questionnaire conducted a minimum of one year after operation. Thirty patients (75 per cent) after SSR were entirely continent and ten patients (25 per cent) had occasional episodes of incontinence. Each patient with a colostomy was incontinent and 25 (66 per cent) had leaks from their appliance (12 frequent; 13 occasional). Patients after APER avoided more items in the diet and took more medication to control their bowel habit than patients after SSR. Fifteen of the 18 patients (83 per cent) who were employed before SSR returned to work after operation; only 6 of 15 patients (40 per cent) returned to work after APER (P less than 0.05). Sexual function was impaired in 6 of 20 men (30 per cent) after SSR and in 12 of 18 men (67 per cent) after APER (P less than 0.06). Depression was significantly more prevalent after APER than after SSR. Patients with low rectal cancer who are treated by modern sphincter saving resection have a quality of life superior to those who are treated by APER.
 ...
PMID:The quality of life after rectal excision for low rectal cancer. 687 35


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>