Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Patients suffering from temporomandibular joint dysfunction syndrome (TMJS) and healthy volunteers were examined by means of MMPI questionnaire and electromyography (masseter, anterior temporal and anterior digastric muscles) at rest and during natural chewing. In response to mental load (arithmetic chain task) TMJS patients showed an increase in postural activity and partly rhythmical short augmentations above the mean level of this activity. Chewing potentials were considerably diminished in patients compared with controls. There was evidence for neurotic disorders in the patients MMPI (neurotic triad: higher scores on hypochondria, depression, hysteria). Significant differences (multivariate variance and discriminant analysis: P less than 0.001) between patients and controls were found both in the group with psychic signs (MMPI scales) and in the group of quantitative electromyographic parameters. However, a sufficient discrimination was only obtained by a combination of both parameter groups. The results show that probably psychic dynamics, as well as the structure of neuromuscular activity within the masticatory system, are important in the aetiopathogenesis of TMJS.
 ...
PMID:Personality and quantified neuromuscular activity of the masticatory system in patients with temporomandibular joint dysfunction. 316 59

The MMPI and MCMI were administered to 163 former opiate addicts who were being maintained in a methadone program affiliated with an urban hospital. Highest group mean MMPI scores were found for Psychopathic Deviate, Depression, Hypomania, and Hysteria. For the MCMI, highest group mean clinical syndrome scores were found for Drug Abuse, Alcohol Abuse, Anxiety, and Dysthymia; highest personality disorder scores were found for Antisocial, Narcissistic, Histrionic, and Paranoid. The MCMI Drug Abuse Scale identified only 49% of subjects as having a recurrent or recent history of drug abuse. Frequency and factor analyses documented the heterogeneity of the population with respect to clinical syndromes, as well as the prevalence of personality disorders (86% had elevations on MCMI Personality Scales). Factor and correlational analyses did not provide strong evidence of similar factor structure or convergent validity of the MMPI and MCMI with this population.
 ...
PMID:Psychopathology of opiate addiction: comparative data from the MMPI and MCMI. 321 33

The present investigation was designed to study the effect of anger on colon motor and myoelectric activity in irritable bowel syndrome. Patients with irritable bowel syndrome were compared with normal controls during resting and two anger stressors: criticism of performance on an intelligence test and during a delay of assistance for a diagnostic procedure. At rest patients with irritable bowel syndrome had higher motor and spike potential activity than normal subjects; however, the difference was only significant for spike activity. Anger significantly increased colon motor and spike potential activity in the groups compared with the resting state. Patients with irritable bowel syndrome produced significantly higher motor and spike potential activity when angered. They also reported themselves to be more hostile and appeared angrier than normal controls after the study. However, they did not report themselves to be more anxious or depressed, suggesting that the observed changes in colonic function of both groups were due to anger. Patients with irritable bowel syndrome scored significantly higher than controls on the Minnesota Multiphasic Personality Inventory scales of hypochondriasis, hysteria, and depression, but these personality factors did not significantly influence their anger level before the study. The results are discussed in terms of the role of learning in the colon and the abnormal reinforcement of bowel behavior in patients with irritable bowel syndrome.
 ...
PMID:Effect of anger on colon motor and myoelectric activity in irritable bowel syndrome. 335 Feb 84

Two breast cancer groups (mastectomised or chemotherapeutic intervention) and a control group of healthy female nurses were given a demographic questionnaire and the Minnesota Multiphasic Personality Inventory. The personality profiles of all three groups emerged as significantly different from each other on all scales with the exception of social introversion and psychopathic deviance. Both cancer groups displayed inflated scores on the clinical scale Depression. A separate series of univariate F tests revealed that the mastectomised patients were characterised by elevated scores on the clinical scales Hypochondriasis, Depression, Hysteria, Masculinity-Femininity and Schizophrenia compared to normals. The discriminant analysis confirmed that between the clinical groups the mastectomised patients exhibited higher scores (compared to those receiving chemotherapy) along the scales Hypochondriasis, Paranoia, Psychaesthenia, Schizophrenia and Hypomania, the latter 4 scales constituting the psychotic tetrad.
 ...
PMID:Psychological characteristics of breast cancer patients. 350 15

Five theories advocate the existence of psychogenic factors in the etiology of cardiovascular diseases. The first of these theories involves a behavioral pattern. Pattern A is predictive of cardiovascular diseases and their risk factors. The second of these theories implies three personality patterns: IRA (Impulsiveness, Repression, Aggressiveness), HHD (Hypochondriasis, Hysteria, Depression) and SAD (Stress, Anxiety, Depression). IRA discriminates significantly people with cardiovascular diseases from healthy subjects. IRA-like patterns account for some 60% of the variance. HHD discriminates to some degree people who show thrombopenia as a reaction to stress. Cardiovascular patients stereotype their defenses and seem to cluster in two subamples: 66% of them repress their aggressiveness and 34% use opposite defense mechanisms. SAD is a reliable predictor; stressful events constitute a risk factor, mainly in anxious or depressed and hostile subjects.
 ...
PMID:Psychological etiology in cardiovascular disorders. Basic findings and new trends. 351 51

A study of 402 individuals with marginal arterial hypertension (MAH) and patients with essential hypertension (EH), stages 1, 2 and 3, demonstrated a variety of psychopathologic syndromes (hypochondria, anxiety, hysteria, depression, cardiophobia) in 52.8, 77.3, 82.5 and 80%, respectively. Specific personality features have been identified as pertaining to MAH (hyperthymism, sthenism, demonstrativeness, psychasthenia) and EH (psychasthenia, intraversion, cycloidy).
 ...
PMID:[Personality traits of persons with borderline arterial hypertension and patients with essential hypertension]. 356 Jun 35

Thirty patients who committed wrist cuttings were divided into four groups according to the patients' psychiatric diagnosis: hysteria group, depression group, adolescent behavioral disorder group and other diagnostic group. In the hysteria group, wrist cutting was considered as an expression of the patients' unconscious intention to seek sympathy for themselves from other people. In the depression group, wrist cutting seemed to be a preliminary rehearsal of suicide. In the adolescent behavioral disorder group, internal conflicts in adolescence or discordance with the patients' parents seemed to be the chief motivations of wrist slashing. The core groups were the hysteria and adolescent behavioral disorder groups, and the peripheral groups were the depression group and others.
 ...
PMID:A clinical study of 30 wrist cutters. 359 59

Nervous bladder symptoms without any established organic causes would appear to be a psychosomatic illness that usually affects married women in midlife. The majority of these patients manifest serious neurotic disorders such as anxiety neurosis, hysteria, phobia, and depression or larvate depression. It is often possible to identify psychosexual disorders in these patients. The predominant situations that seem to trigger irritable bladder symptoms are: sexual intercourse that ends unsatisfactorily for physical or psychological reasons, a partnership conflict, or even a separation conflict. Patients with a hysterical personality structure who are dominated by Oedipus or phallic problems and who, by inhibiting the sexual impulse, frequently suffer from sexual disorders may, in a situation experienced in such an atmosphere of conflict, regress to the stage of urethral erotism; at this stage, the symptoms serve as self-punishment as well as reduction of the fear of guilt and punishment; the unconscious vexation and frustration manifest themselves in these symptoms. In the case of depressive patients, unconscious anger and helplessness can be manifested as irritable bladder symptoms. As a result of the close connection between these urinary disorders and sexual disorders, irritable bladder symptoms without any established organic causes would appear not to be a urological but rather a covert functional sexual disorder.
 ...
PMID:[Psychosomatic aspects of irritable bladder. A review]. 371 43

Somatization, hypochondriasis, and hysteria have often been considered as associated features of the borderline personality disorder. This study was designed to characterize these three syndromes in the borderline patient. Inpatients with DSM-III borderline personality disorder were compared with controls with dysthymic disorder. Scales and items from standardized rating instruments which measured the three syndromes were scored and compared between groups. Although the hysteria-obvious and hypochondriasis scales of the MMPI and the Hamilton Depression Scale item measuring hypochondriasis were elevated in the borderline group, there were no significant differences between groups. Scores of dysthymic patients significantly exceeded those of borderline patients on four of five MMPI codetypes measuring the three syndromes. Findings are discussed in light of previous psychodynamic, empirical, and research literature.
 ...
PMID:Characterizing somatization, hypochondriasis, and hysteria in the borderline personality disorder. 371 48

Hysterical symptoms are defined as complaints that are not fully explained by organic or functional neurological disease. Hysterical symptoms are common in neurological practice, accounting for about 1% of neurological diagnoses. Of those with neurological hysterical symptoms, about 80% will not have the hysterical personality, and about 80% will not have Briquet's hysteria. Some 60% will have a physical disease and perhaps as many as 50% will have recognizable psychiatric illness, particularly depression. Others may have unrecognized physical or psychiatric illness. Many hysterical symptoms may be understood in terms of abnormal illness behaviour.
 ...
PMID:Hysteria--a neurologist's view. 372 4


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>