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Query: UMLS:C0011570 (depression)
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For the past twenty years women's complaints in the microelectronics industry have often been diagnosed as mass psychogenic illness, despite evidence of potential exposure to organic solvents, which have been associated with affect and mood changes. In the present study, the standard version of the Minnesota Multiphasic Personality Inventory (MMPI) was used to evaluate affective and personality disturbance among 63 former microelectronics workers (56 women and 7 men) over a two-year period of time. In both 1986 and 1988, the former workers obtained mean scale score elevations beyond two standard deviations above the normative sample (T = greater than 70) on the MMPI clinical scales of schizophrenia, hypochondriasis, psychasthenia, depression and hysteria. For most scales, 86-88 mean score differences did not attain the 0.05 significance level (two-tailed paired t-test) and no significant differences were observed for 86-88 comparison scale scores = greater than 70 (McNemar paired statistic). Although there were too few men to perform gender comparisons, men scored higher than women on 5 scales and all of the men had scores = greater than 70 on hypochondriasis, depression, hysteria, psychasthenia and schizophrenia. These findings reveal that these former microelectronics workers manifested affective and personality disturbances, consistent with organic solvent toxicity, which persisted over a two year period, indicating that they were not reactive, transient hysterical neurosis.
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PMID:Stability of psychological impairment: two year follow-up of former microelectronics workers' affective and personality disturbance. 161 89

This study investigated the prevalence of alexithymia and its relationship with somatic complaints in a sample of 118 general psychiatric out-patients. Of the sample 39.8% scored in the alexithymic range of the Toronto Alexithymia Scale. Compared with the non-alexithymic patients, the alexithymic patients scored significantly higher on several Minnesota Multiphasic Personality Inventory (MMPI) scales that collectively measure a diverse and extensive range of somatic symptoms and bodily concerns. In addition, the alexithymic patients had significantly higher levels of anxiety, depression, and general psychological turmoil. Although the alexithymic and non-alexithymic patients did not differ on the MMPI Repression and overall Hysteria Scales, which reflect the defenses of denial and repression, the alexithymic patients had significantly less ego strength and were significantly more dependent and more likely to engage in impulsive and acting out behaviours. The overall pattern of results is consistent with the view that alexithymic individuals are prone to both 'functional' somatic symptoms and symptoms of emotional turmoil because they are not well equipped psychologically.
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PMID:Alexithymia and somatic complaints in psychiatric out-patients. 161 82

The role of psychological factors in the course of primary headache syndromes is still controversial. Using the Minnesota Multiphasic Personality Inventory (MMPI) we investigated the personality profiles of 434 headache patients (160 migraineurs, 95 with tension type headache, 30 with cluster headache and 149 with combination headache) in accordance with the IHS criteria. In the first three MMPI scales (hypochondria, depression, hysteria) there was a slight increase in T mean values to over 60, but still in the range of two standard deviations of the normal population. There were no statistically significant differences between the four headache groups and between patients with and without analgesic abuse. It was impossible to distinguish headache groups on the basis of their personality profiles by means of reclassification with discriminant analysis. In a cluster analysis, patients with cluster headache showed the highest number (20%) of abnormalities, but also the highest percentage (13%) of completely normal results. Our findings--a cross section analysis of personality profiles--contradict many other MMPI-based studies.
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PMID:MMPI personality profiles in patients with primary headache syndromes. 179 May 71

This chapter outlines the recorded epidemiological history of PVFS (including the early epidemics of myalgic encephalomyelitis) and the development of the concept, including the realisation that endemic cases also occur. Cases of PVFS are still not recorded by the Surveillance Centre for Communicable Diseases, so it is very difficult to detect and monitor any outbreak in the community, since each GP may only have two or three such patients and would, therefore, not be aware of an epidemic in the community as a whole if it occurred. Epidemiological issues raised by the early epidemics, including the delineation of the syndrome, the question of bias, the role of hysteria and the role of depression; the issue of symptom distribution, and its implications for aetiology; and a multiaxial framework for understanding the association with psychological symptoms are discussed. The value of a future multidisciplinary research programme designed to disentangle direct and predisposing causes of PVFS is emphasised.
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PMID:Post-viral fatigue syndrome. Epidemiology: lessons from the past. 179 93

Thirty alcoholics treated as inpatients were administered the Multi-phasic Questionnaire (MPQ), a short version of MMPI, to study their personality pattern. Results showed highest loading on depression (85%) and lowest on anxiety (3%). A significant correlation was found between scales of psychopathic deviance and hysteria. Age of problem drinking under 35 years and poor PQ level were found to be associated with depression and psychopathic deviance. Clinical diagnosis was corroborated by the findings of the MPQ. The findings of the present study may be utilised to screen adolescents from alcoholic families for preventive measures.
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PMID:Multi-phasic Questionnaire profile of alcoholics and related factors. 179 15

This study (N = 115) compared the abilities of the Faschingbauer Abbreviated Minnesota Multiphasic Personality Inventory (FAM), the Midi-Mult, and the standard MMPI to predict response to conservative medical treatment for low back pain, as assessed by patient ratings of pain intensity 6 to 12 months later. The results indicated that all three inventory formats yielded significant correlations between the Hypochondriasis, Depression, and Hysteria scales and follow-up pain ratings. Less consistent findings were obtained with other scales and indices. The results provide tentative support for the clinical and research utility of these abbreviated MMPIs in substituting for the standard MMPI in outcome studies with back pain patients.
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PMID:MMPI short forms as predictors of response to conservative treatment for low back pain. 183 4

This study investigates the possibilities to identify, within a group of acute low-back pain patients, individuals with psychogenic etiology to pain. 26 acute back pain patients and 25 healthy control subjects were tested with the Minnesota Multiphasic Personality Inventory Hysteria: (Hs), Hypochondria (Hy), Depression (D); Cesarek-Marke Personality Scale: Aggression (Agg), Defence of status (Dst), Guilt (Gui); Mood Adjective Check List: (Hedonism, Activity, Calmness = Hed, Act, Clm) and a 'pain questionnaire' including 'pain drawing'. Differences between groups and correlation patterns between test variables indicate that a combination of Hs, Hy, D, Dst, Gui, Hed, Act, Clm as well as predisposition to somatization, Som (a quantification of pain drawing) provides a useful predictive screening instrument.
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PMID:Personality traits in patients with acute low-back pain. A comparison with chronic low-back pain patients. 183 80

36 patients with rheumatoid arthritis and 44 patients with chronic low back pain were psychologically tested by the MMPI-201, Self-concept of Invalidism Scale, Impact of Pain on the Patients' Lives Scale, and "Pain Games" Scale. Patients with rheumatoid arthritis show significantly higher values at the depression and hypomania scale, while those with chronic low back pain manifest significantly higher values at the hysteria scale of the MMPI-201. This latter group also manifests significantly higher values at the Self-concept of Invalidism Scale and at the "Pain-Game" Scale.
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PMID:[Comparison of patients with rheumatoid arthritis and chronic backache from the aspect of psychological factors]. 183 49

This study aimed to investigate the psychological characteristics of chronic fatigue syndrome (CFS: Holmes et al. 1988). A battery of psychometric instruments comprising the General Health Questionnaire (GHQ), the Beck Depression Inventory (BDI), the Minnesota Multiphasic Personality Inventory (MMPI) and the Lazarus Ways of Coping (WoC) inventory, was administered to a sample of clinically-defined CFS sufferers (N = 58), to a comparison group of chronic pain (CP) patients (N = 81) and to a group of healthy controls matched for sex and age with the CFS sample (N = 104). Considerable overlap was found between CFS and CP patients at the level of both physical and psychological symptoms. This raises the possibility that CFS sufferers are a sub-population of CP patients. However, while there was some commonality between CFS and CP patients in terms of personality traits, particularly the MMPI 'neurotic triad' (hypochondriasis, depression and hysteria), CFS patients showed more deviant personality traits reflecting raised levels on the first MMPI factor, emotionality. Moreover, results were not consistent with the raised emotionality being a reaction to the illness, but rather were consistent with the hypothesis that emotionality is a predisposing factor for CFS. The majority of CFS patients fell within four personality types, each characterized by the two highest MMPI scale scores. One type (N = 20) reported a lack of psychological symptoms or emotional disturbance contrary to the overall trend for the CFS sample. This group conformed to the ICD-10 classification of neurasthenia.
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PMID:Psychiatric symptoms, personality and ways of coping in chronic fatigue syndrome. 187 40

Thirty consecutive patients with globus sensation who were referred to a psychosomatic clinic prospectively underwent otolaryngological, videokinematographic, and manometric examinations of pharynx and esophagus to evaluate whether morphological abnormalities or motility disorders underlay their symptom. When indicated by findings, 24-hour pH-metry, scintigraphy of bolus transport, and esophagogastroscopy were performed. Seven patients were shown to have achalasia, 10 had "hypochalasia" (lower esophageal sphincter relaxation less than 75% with esophageal contraction abnormalities but no complete distal aperistalsis), and 1 had diffuse esophageal spasms; 2 patients had also hyperplastic lingual tonsils, 1 had tonsillitis, and 1 had a cervical spondylophyte. Nutcracker esophagus and nonspecific contraction abnormalities were found in 7 patients, and gastroesophageal reflux with esophagitis and a low lower esophageal sphincter resting pressure was found in 1; only 3 patients had normal esophageal motility. None had volunteered dysphagic symptoms at primary evaluation. Psychometric investigations in consenting patients showed no higher mean scores for state and trait anxiety, depression, hysteria, and hypochondriasis than in general medical outpatients. Esophageal motor disorders may, before giving rise to dysphagia, be sensed more vaguely and induce the globus sensation. However, only disappearance of the sensation after treatment allows inferring an etiological significance of such a disorder.
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PMID:High incidence of esophageal motor disorders in consecutive patients with globus sensation. 195 17


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