Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of the immunity state on the clinical course of stomach ulcer was studied. The study involved 50 patients (38 men and 12 women being 17-67 years old) with stomach ulcer (n = 14) and duodenal ulcer (n = 36) in the acute condition and 25 healthy blood donors. Twenty-seven patients underwent an immunology study. It was revealed that the evident increase of circulatory lymphocyte apoptosis (> 10), which is associated with the depression of their proliferative activity in vitro culture, is recorded with 40.7% of patients (11/27). It was also revealed that a high level of circulatory lymphocyte apoptosis and apoptosis-associated dysfunctions are found more frequently in people with long-term and complicated clinical course.
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PMID:[Abnormalities in stomach and duodenal ulcer immunoregulation]. 1651 12

Anxiety and depression levels in 25 duodenal ulcer patients were compared with equal numbers of age and sex matched normal controls, hospitalised patients with nonpsychosomatic medical illnesses and inpatients with neurosis. Sinha's anxiety scale and Hamilton's rating scale for depression were used to measure the levels of anxiety and depression respectively. Patients with duodenal ulcer were significantly more anxious and depressed as compared to normal subjects and patients with medical illnesses. Duodenal ulcer patients were significantly less anxious and depressed as compared to neurotics. Therapeutic role of tricyclic antidepressants in management of duodenal ulcer is briefly discussed.
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PMID:EMOTIONAL FACTORS IN DUODENAL ULCER. 2876 58


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