Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The changes occurring in specific mood states in response to alterations in physical training were assessed in college varsity swimmers. The Profile of Mood States (POMS) was administered at regular intervals during training seasons over a four-year period to 84 female and 102 male swimmers. It was found that female and male swimmers displayed similar mood responses during training in total mood as well as the specific moods of depression, anger, vigor, fatigue, and confusion. Each of these mood states fluctuated correspondingly with alterations in training yardage, with the exception of tension, which remained elevated while training was being reduced. Tension also was higher (p less than 0.05) in the female swimmers in each of the seasons. It is concluded that: 1) changes in specific mood states during training are similar between female and male swimmers, with the exception of tension, and 2) specific mood factors increase and decrease in accordance with alterations in training distance, with the exception of tension, which does not decrease in response to reductions in training.
...
PMID:Changes in mood states during training in female and male college swimmers. 179 3

These are the final results of a survey of sleep-disordered breathing, which examined objective and subjective information from a large randomly selected elderly sample. We randomly selected 427 elderly people aged 65 yr and over in the city of San Diego, California. Twenty-four percent had an apnea index, AI, greater than or equal to 5 and 62% had a respiratory disturbance index, RDI, greater than or equal to 10. Correlates of sleep-disordered breathing included high relative weight and reports of snoring, breathing cessation at night, nocturnal wandering or confusion, daytime sleepiness and depression. Body mass index, falling asleep at inappropriate times, male gender, no alcohol within 2 hr of bedtime and napping were the best predictors of sleep-disordered breathing. Despite statistical significance, all of the associations between interview variables and apnea indices were small. No combination of demographic variables and symptoms allowed highly reliable prediction of AI or RDI.
...
PMID:Sleep-disordered breathing in community-dwelling elderly. 179 80

The realization that many intensive care patients develop psychoreactive problems ranging from confusion to depression to frank mutism led us to include Dehydrobenzperidol (DHB) in our analgesia and sedation scheme. The early prophylactic administration of this drug was found to be particularly effective in the prevention of delirium following an alcohol and/or drug overdose.
...
PMID:[Psychopharmacologic aspects in intensive care medicine]. 181 35

All incident cases of clinically diagnosed Alzheimer's disease were identified through the unique record linkage system of the Mayo Clinic. Thirty-nine (32%) of the sample of 122 had a psychiatric history that preceded the onset of CDAD by at least 3 years. Twenty-five percent of the study population had had an episode of delirium within 2 years of the onset of CDAD. Eighty-four percent of the cases had psychiatric symptoms in the course of CDAD that were documented in their medical records. Specific symptom patterns included agitation, combativeness, confusion and disorientation, depression, psychosis, and wandering. These symptoms occurred more frequently in clusters than singularly.
...
PMID:Psychiatric symptoms in cases of clinically diagnosed Alzheimer's disease. 185 24

Studies based on random samples of adult deaths in 1969 and 1987 show that, although more people in the recent study were living alone in the year before they die (32 per cent compared with 15 per cent in the earlier study), there had also been an increase in the proportions living in institutions and being admitted to hospital in the 12 months before their death. More of those dying in 1987 than in 1969 had had a home help, whereas the proportion receiving care from district nurses was similar for the two studies and the amount of home visiting by general practitioners had fallen. A higher proportion of those dying of cancer in 1987 than in 1969 were thought to have known that they were dying (44 per cent against 16 per cent) and that they had cancer (73 per cent compared with 29 per cent). However, the proportion of relatives and others who thought the dying person's awareness, or lack of awareness, of the prognosis was 'best as it was' was lower for people dying of cancer in the more recent study (57 per cent against 69 per cent). The symptoms reported for those dying in 1969 and 1987 were generally similar but more of those who died in 1987 had suffered from mental confusion, depression and incontinence for a year or more. This reflects the increased age at which people were dying in the later study: longer life was sometimes associated with the prolongation of unpleasant symptoms.
...
PMID:Changes in life and care in the year before death 1969-1987. 185 28

1. In a multicenter, placebo-controlled, double-blind clinical trial in 155 elderly patients with cognitive decline, glycosaminoglycan polysulfate was found to be a therapeutically effective agent in the treatment of old age dementias. 2. Treatment with glycosaminoglycan polysulfate in the daily dosage of 600 LRU, administered on the basis of a divided dosage schedule for 12 weeks, was significantly superior to an inactive placebo on several outcome measures including the Wechsler Memory Scale-Russell Revision (Easy Paired Associates Learning and Immediate Visual Reproduction), Mini Mental State Examination, the Sandoz Clinical Assessment Geriatric (Cognitive Dysfunction and Depression), Hachinski Dementia Scale, Brief Psychiatric Rating Scale (Confusion and Depressive Withdrawal) and Global Improvement Scale of the Clinical Global Impression. 3. Adverse effects with glycosaminoglycan polysulfate were few and mild. The drug was equally well tolerated and equally effective in the two major dementias of old age, i.e., primary degenerative and multi-infarct. The number of abnormal laboratory test readings remained essentially unchanged from pre-treatment to post-treatment.
...
PMID:Glycosaminoglycan polysulfate in the treatment of old age dementias. 186 17

Despite its positive effects on the increased use of multiple assessments and improved assessment validity, the triple-response concept has led to some conceptual and practical confusion. This is mainly due to two problems: (1) a confounding of the content and method of assessment; and (2) an imprecise and vague use of the 'verbal-subjective mode' which has been expanded to include cognitive elements since the introduction of cognitive-behavioural theories and treatments. A new matrix is proposed that clearly distinguishes content and method of assessment. It also defines a separate cognitive/information-processing content area and introduces affect as an additional content area. Thus, four content areas are suggested: behavioural, physiological, cognitive, and affective, which can be measured in three different ways: by means of self-report, observation, and instruments or technical equipment. We point out the implications of these changes for (1) a more appropriate selection of assessment procedures and outcome measures in clinical research; (2) a more adequate individualization of treatment through matching individual response profiles to specific treatments; and (3) an improved understanding of the interrelationship between behavioural, physiological, cognitive, and affective processes in anxiety and depression. Finally, we suggest that the lack of agreement between measures of physiological, cognitive, behavioural and affective changes in some studies may be as much a reflection of the lack of agreement arising from spurious sources of variance within content areas as it is a reflection of the operation of different processes and systems.
...
PMID:The triple response approach to assessment: a conceptual and methodological reappraisal. 188 9

The purpose of this study was to determine the relationship between psychological states as measured by the Profile of Mood States (POMS) inventory and within-subject variation in running economy (RE) in moderately trained male runners (N = 10). Subjects (ages 20-34 yr) were monitored during treadmill running, five times a week (Monday through Friday) for 4 wk, at 2.68, 3.13, and 3.58 m, s-1. Tension, depression, anger, vigor, fatigue, confusion, and a total mood disturbance (TMD) score were assessed every Friday prior to the treadmill running sessions. Oxygen consumption (VO2) was determined via the open-circuit method during each of the three running paces. VO2 values were averaged over 5 d and three speeds for each week (RE) and were correlated with the weekly TMD scores, resulting in a nonsignificant group correlation of r = -0.28. The within-subject group correlation between TMD scores and RE was r = 0.88. This positive correlation indicates that, when the focus of attention was on within-subject variation, weeks featuring more economical values were associated with more positive mental health profiles. Correlations between average VO2 and the six POMS subscales were tension. r = 0.81; depression, r = 0.73; anger, r = 0.58; vigor, r = -0.60: fatigue, r = 0.18; and confusion, r = 0.60. All correlation coefficients except for fatigue were significantly (P less than 0.01) related to average VO2. In conclusion, it appears that short-term fluctuations in RE of moderately trained male runners are closely tied to their mood state.
...
PMID:Mood state and running economy in moderately trained male runners. 188 81

1. Patients with post-traumatic stress disorder (PTSD) often encounter treatment that is complicated by professional bias, personal issues, countertransference, and pathological staff dynamics. 2. Treatment is further complicated by diagnostic confusion, the dual diagnoses of substance abuse or depression, and symptoms that mimic personality disorders or psychosis. 3. The special circumstances of the Vietnam conflict that contributed to the susceptibility and etiology of PTSD are the individual characteristics of those who served, the special nature of the war itself and the military strategies used, and the psychosocial and cultural milieu in which it occurred.
...
PMID:PTSD and the Vietnam veteran: the battle for treatment. 194 21

To develop a psychological profile of professional female athletes, specifically of elite tennis players, 16 professional female tennis players from five countries were given the Profile of Mood States to measure six mood states: tension, depression, anger, vigor, fatigue, and confusion. When age was controlled in the design, older female athletes exhibited the "iceberg profile," i.e., they scored higher on the vigor mood state and lower on all other mood states than college-age women. Younger athletes scored like college-age women. These results only partially support the 1987 work of Morgan, O'Connor, Sparling, and Pate.
...
PMID:Mood states of professional female tennis players. 194 86


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>