Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the radiologic examination of trismus complicating cancrum oris, abnormalities can be detected in the soft tissues, osseous tissues, and temporomandibular joint. In the soft tissue, scar formation may show as a depression in the normal smooth, convex contour of the lateral aspect of the face. There may be a myositis ossificans in the soft tissue, producing bony bars that lead to extra-articular ankylosis. By far the most important changes are in the temporomandibular joint, where there can be varying degrees of joint narrowing, sclerosis of the articular cortex, flattening of the mandibular condyle and occasionally also of the eminentia articularis, osteophytosis, and intra-articular bony ankylosis. Hypoplasia may involve the entire hemimandible or be restricted to its condyloid process. The latter may lead to compensatory enlongation and hypertrophy of the coronoid process. Bony ankylosis of the coronoid process to the posterior wall of the maxilla was seen in three cases. The pathogenesis of these changes is discussed.
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PMID:Radiologic examination of trismus as a complication of cancrum oris. 105 83

Intrathecal morphine in an average dose of 0.01 mg/kg was given to 33 patients between ages 11 and 16 years who had spinal arthrodesis for idiopathic scoliosis. The morphine was administered intrathecally as a 10 cc bolus at the conclusion of the arthrodesis, but before closure. The goal was to study safety in terms of respiratory depression and pain relief. Respirations occurred spontaneously in 30 of the 33 patients within 15 minutes of cessation of anesthesia. Respiratory depression occurred in five patients, four of whom had arterial blood pCO2 levels greater than 60 mm Hg. Thirty-one patients had relief of pain for 8 to greater than 40 hours, averaging 18 hours. Two patients had no noticeable pain relief. There appeared to be no relation between dose and pain relief in this limited dose range. We were unable to duplicate the long duration of pain relief reported elsewhere. We also were unable to decrease the side effects of respiratory depression and nausea to a level reported by others. It may be that the 10 cc bolus injected intrathecally circulates to the brain and ventricles faster than desired, or that factors relating to type of anesthesia or dose need to be considered. Low-dose intrathecal morphine does provide noticeable pain relief in younger patients undergoing spinal fusion. The side effects of nausea and respiratory depression can be managed safely with medication.
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PMID:Intrathecal morphine in younger patients for postoperative pain following spinal fusion. 192 2

Intrathecal morphine in an average dose of 0.01 mg/kg was given to 33 patients between ages 11 and 16 years who had spinal arthrodesis for idiopathic scoliosis. The morphine was administered intrathecally as a 10-cc bolus at the conclusion of the arthrodesis, but before closure. The goal was to study safety in terms of respiratory depression and pain relief. Respirations occurred spontaneously in 30 of the 33 patients within 15 minutes of cessation of anesthesia. Respiratory depression occurred in five patients, four of whom had arterial blood pCO2 levels greater than 60 mm Hg. Thirty-one patients had relief of pain for 8 to greater than 40 hours, averaging 18 hours. Two patients had no noticeable pain relief. There appeared to be no relation between dose and pain relief in this limited dose range. We were unable to duplicate the long duration of pain relief reported elsewhere. We also were unable to decrease the side effects of respiratory depression and nausea to a level reported by others. It may be that the 10 cc bolus injected intrathecally circulates to the brain and ventricles faster than desired, or that factors relating to type of anesthesia or dose need to be considered. Low-dose intrathecal morphine does provide noticeable pain relief in younger patients undergoing spinal fusion. The side effects of nausea and respiratory depression can be managed safely with medication.
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PMID:Intrathecal morphine: dosage and efficacy in younger patients for control of postoperative pain following spinal fusion. 206 32

In elderly patients an unilateral sensorineural hearing loss is frequently associated with a relatively more patent eustachian tube on the involved side. A simple method of investigation is observation under the operating microscope during tubal inflation by the patient. In right-handed patients the abnormally patent tube most often lay on the left side. Powerful self inflation in these patients induces acute hearing loss and vertigo. Acute hearing loss is commoner on the left side. The air bone gap is greater at higher frequencies due to mobility of the stapes, loosening of the incudal joints and the tympanic membrane. In contrast the air bone gap is greater at lower frequencies in otosclerosis or malleus head ankylosis. Minor degrees improve after self inflation is prohibited. In most patients with abnormally patent eustachian tubes further therapy is not necessary after the patient has received precise advice. In only about 20% of the cases is the patient disturbed by a feeling of fullness in the ear, autophony and tinnitus. After stabilisation of weight and blood pressure, a septoplasty with correction of the posterior turbinates may reduce the exspiratory resistance. The most drastic treatment is a collagen injection around the tube. Patients with depression should be treated appropriately.
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PMID:[Unilateral patulous eustachian tube with tinnitus, inner ear damage, vertigo and sudden deafness--collagen injection]. 335 Jul

Progressive inability to open the mouth developed in a cat after trauma to the head. Evaluation revealed a healed depression fracture of the left zygomatic arch and normal temporomandibular joints. Surgical exploration of the fracture confirmed a false ankylosis that developed between the depression fracture and the ramus of the mandible. Treatment included excision of the central portion of the zygomatic arch and a portion of the ramus. The cat regained normal function of its mouth.
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PMID:False ankylosis of the temporomandibular joint in a cat. 367 94

A retrospective study has been made of 355 fractures of the os calcis involving the subtalar joint in order to determine the best method of treatment. A rating system was used to assess the different types of injury. The results were correlated with the pattern of depression of the posterior articular surface, the quality of restoration of this surface and the type of trauma. We conclude that Duparc Stage V fractures require reconstruction/arthrodesis (the Stulz proceedure). Duparc Stage I fractures, and Stage III or IV with grade I depression, should be treated conservatively with early mobilisation. Stage III or IV fractures with grade II or III depression require operation in order to restore and maintain a congruent posterior joint surface to allow early mobilisation.
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PMID:[Statistical study of a series of 355 subtalar fractures of the calcaneus. Therapeutic conclusions]. 407 36

The indications, contraindications, technique, and end results of thirty-four tarsometatarsal truncated-wedge arthrodeses performed for cavus and equinovarus deformity of the fore part of the foot were reviewed. The etiology of deformity included idiopathic pes cavus, equinus deformity of the fore part of the foot, residual club foot, poliomyelitis, and compartment syndromes. With th truncated-wedge arthrodesis the subtalar joint is not violated and selective correction of any combination of depression of the metatarsal head is readily accomplished. By strict adherence to the indications and exacting surgical technique, complications are rare and the end results are uniformly excellent.
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PMID:Tarsometatarsal truncated-wedge arthrodesis for pes cavus and equinovarus deformity of the fore part of the foot. 739 Oct 94

All cases of displaced tibial plateau fractures treated by open reduction and internal fixation at two university hospitals over a 3-year period were retrospectively reviewed. There were 47 fractures in 45 patients. Rigid fixation to allow early motion was the goal in all cases. There were 3 AO type I (wedge) fractures, 20 AO type III (wedge/depression) fractures, and 24 AO type IV (comminuted/bicondylar) fractures. Cases were classified into three groups depending on the amount of hardware used to obtain fixation (a single buttress plate, group 1; a buttress plate and interfragmentary lag screws, group 2; or medial and lateral buttress plates with or without lag screws, group 3). In group 1, there were 20 fractures and no instances of deep-wound infection or postoperative ankylosis. In group 2, infection occurred in 6 of 19 fractures (32%), all of which also developed significant ankylosis including 1 patient who underwent arthrodesis. In group 3, 7 of 8 (87.5%) knees became infected, and the patients experienced other devastating complications, including ankylosis (n = 3), arthrodesis (n = 2), knee disarticulation (n = 1), and above-knee amputation (n = 1). Patients whose knees became infected underwent an average of five subsequent surgical procedures. These results suggest that patients with comminuted tibial plateau fractures requiring either two buttress plates or a single plate with additional interfragmentary lag screws would probably be better managed by either non-operative treatment or limited internal fixation.
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PMID:Complications of internal fixation of tibial plateau fractures. 819 73

During the period of October 1985 through March 1995, 25 patients presented to the Veterans Affairs Medical Center, Miami with a chief complaint of chronic pain status post calcaneal joint depression fracture. Their acute injury was treated conservatively at this and various other institutions. Nine patients were managed conservatively with orthotics, University of California Biomechanics Laboratory braces (UCBLs), shoe modification, or prosthetics. Sixteen patients underwent hindfoot fusions. Good to excellent results were obtained in 15 of the 16 fusions. The remaining patient, having an isolated subtalar fusion, was later diagnosed with multiple sclerosis. Proper evaluation of the chronic pain patient is critical when mapping out an appropriate treatment plan. Hindfoot arthrodesis with soft tissue decompression is a successful tool in eliminating chronic pain due to malunited depression fractures.
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PMID:The surgical dilemma of the malunited calcaneal joint depression fracture: the VAMC Miami experience. 872 81

Thirty-two patients with acute calcaneal fractures presented to the Veterans Affairs Medical Center, Miami, Florida, from October 1985 through March 1994. Twenty-three of these patients were open-reduced, and nine were immobilized in a short leg nonweight-bearing cast for a minimum period of 6 weeks. Of the 23 patients who had open reduction with internal fixation, 74% reported excellent results, 13% reported good results, 4% had fair results, and 9% had poor results. Of the nine patients who did not undergo open-reduction internal fixation, three subsequently developed poor results, two developed fair results, three developed good results, and one had no complaints. Of these nine patients, three ultimately underwent successful hindfoot arthrodesis. This article reviews the current literature and discusses the experiences of the Podiatry Service in the VA Medical Center in Miami, Florida, with respect to the surgical management of the acute calcaneal joint depression fracture.
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PMID:Surgical management of the acute calcaneal joint depression fracture: the VAMC Miami experience. 883 80


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