Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011551 (depersonalization)
 1,117 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The author reports the use of behavior therapy in the treatment of two cases of severe intractable depersonalization. Outcome criteria included full psychiatric assessment, patients' self-ratings, and psychometric test scores. Treatment by flooding was highly effective in one case, and associated obsessive symptoms and anticipatory anxiety were substantially decreased in the other. Behavioral techniques may prove especially helpful in cases in which anticipatory anxiety, phobic avoidance, and obsessive perseveration are exacerbating features.
 ...
PMID:Severe depersonalization treated by behavior therapy. 71 75

Correlations (r = 0.50) were found between the numbers of different psi (paranormal) experiences and the numbers of temporal lobe signs within a population of university students (n = 99). The strongest correlation of 0.60 occurred with a cluster of signs that are similar to symptoms reported by patients who show chronic foci in the mesiobasal temporal lobe. However, there were no significant correlations between numbers of different psi experiences and clusters of control items or a lie scale. Specific analyses of the 140 items of the inventory indicated only 23 reached statistical criterion (p less than .001). Of these 17 were direct temporal lobe signs that implied deepened affect, auditory-vestibular experiences (vibrations, hearing one's name called), olfactory auras, perseveration ("forced" thinking), depersonalization, and sense of the personal. Five items involved beliefs about exotic phenomena or philosophical ideas. Only one item was from a control cluster. These results support the hypothesis that mystical or paranormal experiences are associated with transient electrical foci within the temporal lobe of the human brain. The repeated occurrence of these experiences within normal individuals may be embedded within a more complex symptomatology of temporal lobe signs.
 ...
PMID:Temporal lobe signs and reports of subjective paranormal experiences in a normal population: a replication. 402 38