Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

OEsophageal manometry, acid perfusion test and recording of oesophageal pH after gastric filling with 300 ml HCI were carried out in 55 patients with at least one symptom of gastro-oesophageal reflux (GER). None of the patients complained of dysphagia or had a history of haemorrage, but 19 had oesophagitis on endoscopy. pH probe recordings showed evidence of GER in 72% of the patients, and acid perfusion was painful in 44%. The resting lower oesophageal sphincter pressure was below normal in 20%. Thirty-eight p. cent had peristaltic disorders associated with significantly decreased sphincter pressure. In this category of patients, oesophageal pH recordings constitute the best method for diagnosing GER. Apositive acid perfusion test indicates that the clinical symptoms are due to abnormal sensitivity of the mucosa to hydrogen ions. Manometry is useful for a study of motor disorders resulting from GER, but insufficient to determine whether or not GER is present.
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PMID:[Gastro-oesophageal reflux syndrome. Functional exploration of the oesophage in 55 patients (author's transl)]. 742 98