Gene/Protein
Disease
Symptom
Drug
Enzyme
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Pivot Concepts:
Gene/Protein
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Target Concepts:
Gene/Protein
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Query: UMLS:C0011168 (
dysphagia
)
15,644
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Esophageal mucosal calcinosis (EMC) is a rare cause of
dysphagia
with high morbidity. We present a patient who experienced melena and 3 months of solid and liquid
dysphagia
along with bilateral lower extremity pain, erythema, and edema later determined to be calcific uremic arteriolopathy (CUA), or calciphylaxis. An esophagogastroduodenoscopy revealed nodularity and linear ulcerations in the upper third of the esophagus. Histology showed active inflammation and ulceration with small foci of subepithelial and intraepithelial calcification consistent with EMC. There is no known treatment for this disorder.
Sodium thiosulfate
, typically used to treat CUA, did not improve her
dysphagia
.
...
PMID:Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis. 2893 55
