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Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twenty patients with a remote history of poliomyelitis and recent or progressive dysphagia were evaluated with cinefluorography. Radiographic abnormalities were present in the pharynx in varying degrees in all but one of the patients. Findings included atrophy of the prevertebral soft tissues, unilateral or bilateral weakness of the tongue or soft palate, paresis or paralysis of the pharyngeal constrictor muscle, incomplete or absent epiglottic tilt, poor laryngeal elevation, poor laryngeal closure with laryngeal penetration, aspiration (often without a cough), and luminal narrowing at the cricopharyngeal level. Other structural lesions included a Zenker diverticulum in one patient, bilateral pharyngeal pouches in five, and a unilateral pouch in one. Additional structural lesions contributing to dysphagia were found in two other patients, including a focal stricture in the cervical esophagus in one patient and two stenotic rings in the distal esophagus in another. In four patients (one of whom had the Zenker diverticulum), the inferior constrictor muscle contracted forcibly above a prominent cricopharyngeus muscle, perhaps contributing to the formation of the diverticulum. It is important to examine postpolio patients with dysphagia carefully with dynamic imaging to assess the severity of decompensation and to detect other lesions that may be treatable. The information derived can be used to guide management.
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PMID:Swallowing dysfunction in the postpolio syndrome: a cinefluorographic study. 172 82

Questionnaires pertaining to swallowing function were mailed to 220 members of postpolio support groups in Connecticut. Of the 109 responses, 80 individuals reported having no difficulty with swallowing, while 29 reported having either intermittent or consistent swallowing problems. Twenty-one of the 29 were seen for videofluoroscopic swallowing studies and pulmonary function testing. The swallowing studies showed that 43% of these individuals had difficulty with bolus control, 19% with delayed swallow response, and 81% with decreased pharyngeal transit. Although none of these individuals were observed to aspirate, two were judged to be at significant risk. Incidence of dysphagia within the group of polio survivors was estimated to be approximately 18%. Seventeen of the 20 postpolio subjects with dysphagia also demonstrated decreased breathing capacity. Although moderately to severely depressed values in the pulmonary function measures accompanied moderate dysphagia in certain postpolio individuals, reduced values in these same measures were also present in individuals with minimal swallowing dysfunction. Therefore, although impaired breathing may complicate swallowing dysfunction and vice versa, it does not appear that one can be predicated from the other. Management of dysphagia in postpolio individuals is discussed.
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PMID:Incidence and nature of dysphagia in polio survivors. 174 59

Twenty consecutive patients were evaluated for reports of dysphagia from post-polio clinics. Only half the patients reported a history of swallowing problems at the time of their acute poliomyelitis. Each patient received a videofluorographic evaluation of the oral and pharyngeal phases of swallowing, and then was provided with recommendations to improve swallowing skills. A follow-up questionnaire was sent to all patients. The respondents had an average interval of 12 months since the initial evaluation. Of the 18 patients responding to the questionnaire, 14 (77%) reported regular use of the swallowing suggestions. Comparison of pre-evaluation results to followup of the 18 respondents yielded a statistically significant decline in the frequency of choking (p = 0.0156) and food sticking in the throat (p = 0.0195). We conclude that a dysphagia program can result in significant improvement of the swallowing symptoms reported with the post-polio population.
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PMID:Evaluation, treatment, and follow-up results of post polio patients with dysphagia. 190 34

Although they are delayed, progressive symptoms occurring after polio have recently received considerable attention, dysphagia in patients who have had polio has not been well-studied. The findings of historical, neurologic, and cineradiographic examinations in 13 patients with dysphagia who had had polio are presented. Historical evidence indicates that progressive dysphagia is among the worsening problems encountered by some patients several decades after their acute polio illness. Thorough evaluation of dysphagia symptoms in patients who have had polio is indicated to determine optimal feeding management and to search for treatable contributing factors.
Dysphagia 1991
PMID:Dysphagia occurring after polio. 191 44

In the literature there are rare reports on Japanese encephalitis (JE) mimicking poliomyelitis or presenting as respiratory paralysis. A case of JE presenting as respiratory paralysis is described. The 22-year-old male was well until five days earlier, when he experienced the acute onset of headache and fever. Four days after onset he developed dysphagia and respiratory difficulty, and a tracheotomy was performed. The following day he lapsed into semicoma and the respiration had to be maintained by an artificial ventilator. He regained consciousness by the 10th day after onset. He became able to comprehend questions and express himself by gestures. But the respiration was still paralytic, and assisted ventilation via a tracheotomy had to be continued. The case was clinically diagnosed as encephalitis. Bulbar poliomyelitis was initially considered due to the clinical features of aseptic meningitis, respiratory paralysis, pharyngeal paralysis with pooling secretions in the pharynx, tachycardia and elevated blood pressure. But poliovirus culture obtained from stool and appropriate serological studies were negative. The diagnosis of encephalitis due to JE virus was confirmed by hemagglutination inhibition test (acute phase HI titer 1:320; convalescent phase HI titer 1.1280).
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PMID:Respiratory paralysis as a presenting symptom in Japanese encephalitis--a case report. 255 72

Findings on three postpolio sequelae patients referred for swallowing evaluations are presented. The first patient, a 67-year-old man more than 60 years post onset of polio, complained of frequent coughing and the sensation of foods becoming stuck in his throat during meals. Videofluoroscopic swallowing exam revealed reduced pharyngeal peristalsis and liquid pooling in the pyriform sinus. The second patient, a 59-year-old woman, was more than 30 years post onset of polio and was referred because of progressive dysphagia and hoarseness in the past three years. Videofluoroscopy revealed reduced strength of the oral musculature and reduced pharyngeal peristalsis with pooling of liquids in the pyriform sinus. The last patient, a 50-year-old woman more than 40 years post onset of polio, reported having difficulty with foods sticking in her throat. Swallowing exam revealed a delayed swallowing reflex and reduced pharyngeal peristalsis. Although none of the patients was observed to aspirate, all were considered to be at risk because of the gradual build-up of foods in the pharynx. Noninvasive management procedures and the importance of stress testing the swallowing mechanisms of such patients are discussed. Longitudinal follow-up with these individuals is recommended.
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PMID:Dysphagia in postpolio sequelae: report of three cases. 340 36

The patient who has multiple cranial neuropathies may pose a diagnostic dilemma. The neurologic disorders of amyotrophic lateral sclerosis, multiple sclerosis, myasthenia gravis, and poliomyelitis often cause bulbar dysfunctions such as diplopia, facial weakness, slurred or hypernasal speech, dysphagia, and hoarseness. In general, treatment is supportive and is directed toward restoring or aiding lost function (i.e., tracheostomy, esophagostomy, and cricopharyngeal myotomy). The relative infrequency of these disorders can lead to delays in diagnosis and rehabilitative therapy.
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PMID:Neurologic disorders: amyotrophic lateral sclerosis, myasthenia gravis, multiple sclerosis, and poliomyelitis. 710 59

Of the 250,000 survivors of the polio epidemics, approximately 25% experience progressive muscle weakness known as postpolio syndrome (PPS). Laryngeal function in postpolio patients previously has not been studied. This paper presents data detailing laryngeal function in a group of postpolio patients who had been evaluated for swallowing complaints. Nine patients underwent comprehensive history and physical exam, acoustical voice analysis, and laryngeal videostroboscopic endoscopy. Three patients underwent laryngeal electromyography (EMG) evaluation. Results indicated some degree of phonatory or laryngeal deficit in all subjects. Subjects with dysphagia also demonstrated vocal fold paralysis. EMG revealed decreased recruitment and increased amplitude, findings consistent with EMG studies in skeletal muscle in postpolio patients. Results suggest that postpolio patients who complain of swallowing difficulties are at risk for laryngeal pathology.
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PMID:Laryngeal function in postpolio patients. 783 11

The case of a 69 year old, male patient with slowly progressive dysphagia and an acute exacerbation is presented. He was referred to rule out an organic origin to his disorder. Apart from mild residual weakness of both legs after an acute paralytic poliomyelitis at the age of 20, the physical examination was essentially normal. No upper motor neuron pathology was found. Electromyography showed prevalent spontaneous and chronic denervation of bulbar and skeletal muscles. X-ray cinematography revealed abnormalities of bolus passage. On the basis of history and the benign clinical course over a 2 year follow-up period we assume a post-polio syndrome presenting with only dysphagia.
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PMID:[Post-polio syndrome with isolated dysphagia]. 796 55

In patients with a history of acute paralytic poliomyelitis (APP), late progressive muscle weakness may arise, known as the progressive postpoliomyelitis muscular atrophy (PPMA). In 43 patients with PPMA, 8 were evaluated for recent or late progressive dysphagia. The mean interval between APP and onset of swallow symptoms was 27.1 years (range 23-45); the mean age of the patients was 45.4 years (range 35-52). Initial videofluorography showed signs of slight-to-moderate oropharyngeal dysfunction in 6 patients (delayed swallow reflex, diminished peristalsis of constrictor pharyngeus muscle, diminished laryngeal elevation, retention of bolus). In 2 patients, no abnormalities were found. Seven patients were reexamined after 12-36 months (mean 18). All reported subjective progression of symptoms. Videofluorography showed minor changes in 1 patient and unaltered findings in 6. No signs of aspiration were found either clinically or by video. We conclude that patients with PPMA complaining of late dysphagia do not show a significant loss in oropharyngeal function on 1-3 years follow-up.
Dysphagia 1994
PMID:Dysphagia in postpolio patients: a videofluorographic follow-up study. 800 15


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