Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Nd:YAG laser therapy is an attractive palliative treatment for carcinoma of the esophagus and gastric cardia. Twenty-five patients with these tumors underwent laser therapy over a 2-year period, receiving a total of 52 courses of therapy with 189 treatments. Treatments per course averaged 3.6, with a mean of two courses per patient. Luminal diameter is increased with this method; symptomatic improvement in dysphagia occurred in all patients after one course of therapy. Radiographic improvement also is seen. The complication rate in this series was four (2.1%) of 189 procedures, consisting of one perforation, one tracheoesophageal fistula, one pneumopericardium, and one pneumoperitoneum without leak.
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PMID:Radiographic appearance of the esophagus and stomach after laser treatment of obstructing carcinoma. 348 69

A 52-year-old man had been treated for oral cancer T3 N0 M0 by radical surgery, neck dissection on the right and cervical irradiation (60 Gy). Two months after therapy he presented with dysphagia and hemoptysis. Admission chest X-ray revealed a pneumopericardium. It was caused by a bronchomediastinal fistula due to necrotic metastatic lymph nodes as shown by CT, which also revealed a concomitant pneumomediastinum. The patient died 10 days later from pneumonia. The CT findings were confirmed at autopsy. We conclude that malignant mediastinal lymphadenopathy is a potential cause of pneumopericardium and pneumomediastinum.
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PMID:Pneumomediastinum and pneumopericardium due to malignant subcarinal lymphadenopathy: CT demonstration. 920 46

Pneumomediastinum and pneumopericardium are very rare complications resulting from blunt trauma to the head and neck. We report the case of a 40-year-old male who had been assaulted. He presented to the Emergency Department with bruises to the face and neck and complained of dysphagia. He was found to have extensive subcutaneous emphysema of the face and neck. Imaging revealed the presence of a mucosal tear in the oropharynx leading to pneumomediastinum and pneumopericardium. He was managed conservatively and made an uneventful recovery. This is a very rare but potentially life-threatening complication of blunt trauma to the head and neck. It poses diagnostic difficulties and treatment dilemmas, which are discussed.
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PMID:Mucosal tear in the oropharynx leading to pneumopericardium and pneumomediastinum: an unusual complication of blunt trauma to the face and neck. 1676 5

Per-oral endoscopic myotomy (POEM) is a relatively novel endoscopic technique for the treatment of achalasia. POEM has been shown to have outcomes comparable to those with Heller myotomy, but it is less invasive and has fewer complications. A 72-year-old man with progressive solid and liquid dysphagia underwent POEM, but soon after the procedure went into cardiac arrest; spontaneous circulation returned after 10 minutes of CPR. He was subsequently found to have tension pneumopericardium as a result of the inadvertent use of air instead of carbon dioxide during the procedure. He had a prolonged hospitalization that required an extended stay in the medical intensive care unit. Although rare, POEM can lead to critical, life-threatening complications.
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PMID:Pneumopericardium Complicating Per-Oral Endoscopic Myotomy Due to Inadvertent Use of Air Instead of Carbon Dioxide. 3014 82