Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A number of complications can occur following cervical vertebral fusions of intervertebral disc lesions. These include hypoglossal or recurrent laryngeal nerve paresis, inflammation of the operative wound, injuries of the esophagus and hypopharynx, as well as instability of alloplastic fusion material and spinal cord injury with tetraplegia. Cloward has reported transient postoperative dysphagia in 80% of patients. We describe a patient suffering from persistent dysphagia after cervical fusion. The symptoms were caused by adhesions between the esophagus and prevertebral muscles and a sharp edge of osteochondrosis of the vertebral body. The importance of surgical treatment in such patients is discussed.
 ...
PMID:[Esophageal complications following ventral cervical disc surgery (author's transl)]. 52 32

Radiographic, clinical and pathologic abnormalities of diffuse idiopathic skeletal hyperostosis (DISH) are presented. Definite criteria must be fulfilled to differentiate DISH from other diseases of the spine, especially intervertebral osteochondrosis and ankylosing spondylitis. A case of massive DISH in the cervical spine causing dysphagia is described.
 ...
PMID:[Diffuse idiopathic skeletal hyperostosis as a cause of dysphagia]. 357

Cervical spine disorders which can cause swallowing difficulties (cervicogenic dysphagia; CD) are: chronic multisegmental/MS dysfunction (dysfunction=functional blockade) of the facet joints, changes in physiological curvature of the cervical spine, degenerative changes (anterior osteophytes, anterior disc herniation, osteochondrosis, osteoarthritis), inflammatory rheumatic diseases, diffuse idiopathic skeletal hyperostosis, injuries, conditions after anterior cervical spine surgery, congenital malformations and tumors. According to our clinical observations, degenerative changes in the cervical discs and facet joints and chronic MS dysfunction of the cervical spine facet joints are disorders which can cause swallowing difficulties. However, these disorders have not been recognized enough as the causes of dysphagia and they are not even mentioned in differential diagnosis. Because of the close anatomical relationship of cervical spine with the pharynx and cervical part of esophagus, the consequences of the degenerative changes in the cervical discs and facet joints and chronic MS dysfunction of the cervical spine facet joints such as the changes in the physiological curvature of the cervical spine, changes in elasticity and contractility in the neck muscles and decreased mobility of the cervical spine, adversely affect the dimensions of the pharynx and cervical part of esophagus, that is, swallowing capacity which can result in dysphagia. Degenerative changes in the cervical discs and facet joints are common additional cause of dysphagia in elderly people with disorders of the central control of swallowing (stroke, Parkinson's disease, senile dementia etc). The most important therapeutic options in patients with CD are: medicamentous therapy, physical therapy, manual therapy, kinesiotherapy and surgical treatment. The aim of the conservative therapy in patients with CD is to improve the swallowing capacity (for example, soft tissue techniques, stretching of the shortened muscles, passive and active mobilization of the facet joints). As the patients with CD usually respond well to the appropriate therapy, cervical causes of dysphagia cannot be overlooked in patients with difficulty swallowing, including patients with disorders of the central control of swallowing.
 ...
PMID:[Cervicogenic dysphagia: swallowing difficulties caused by functional and organic disorders of the cervical spine]. 2367 76

Dysphageal complaints in a 65-year-old woman were regarded as a manifestation of mental illness. The autopsy of the patient weighing 32 kg who died from bilateral pneumonia revealed 9-mm osteophytes on the anterior surface of the cervical spine as the cause of dysphagia. Twenty-nine cases of cervical osteochondrosis-induced dysphagia, published in the literature, were analyzed.
 ...
PMID:[Osteochondrosis as a possible cause of pharyngeal dysphagia]. 2434 Dec 33