Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A patient with long-standing cutaneous T-cell lymphoma, mycosis fungoides type (CTCL-MF), developed dysphagia, odynophagia, and weight loss. Endoscopic biopsy of esophageal mucosa demonstrated involvement by CTCL-MF. Although extracutaneous spread of CTCL-MF is common, esophageal involvement is unusual and to our knowledge has not previously been diagnosed antemortem.
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PMID:Esophageal involvement by cutaneous T-cell lymphoma, mycosis fungoides type: diagnosis by endoscopic biopsy. 232 81

Review of the otolaryngologic literature reveals no case reports of mycosis fungoides involving the esophagus. Post-mortem studies report 12 cases of esophageal involvement in 131 autopsies of patients with mycosis fungoides. We describe a 54-year-old man with mycosis fungoides involving the larynx, hypopharynx, and esophagus. Treatment consisted of radiation to this area, with resolution of the patient's hoarseness and dysphagia. The charts of 96 patients with mycosis fungoides treated at our institution were retrospectively reviewed. Three additional cases involving the aerodigestive tract, but not the esophagus, were found. Esophageal mycosis fungoides was an incidental finding in two of seven autopsies at our institution.
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PMID:Mycosis fungoides involving the cervical esophagus. 849 5