Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 54-year-old patient with polycystic kidney disease developed relapsing urinary-tract infections after renal transplantation. In the post-transplantation period he underwent two rejection episodes. The general condition worsened without obvious reason. Six months after transplantation the patient was hospitalized due to gram-negative sepsis. Despite adequate antimicrobial treatment he continued to lose weight and complained of dysphagia. Chest X-ray and computer tomogram of the thorax showed multiple cavitating infiltrations of the lung. A few days later the patient died from an extended subarachnoidal hemorrhage.
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PMID:[Dysphagia, cavernous changes of the lungs and subarachnoid hemorrhage following kidney transplantation]. 748 47

We report a patient with autosomal dominant polycystic kidney disease (ADPKD) undergoing long-term hemodialysis who underwent transcatheter arterial embolization (TAE) of the renal arteries to shrink enlarged kidneys. In 1983, the patient started hemodialysis because of chronic renal failure secondary to ADPKD. However, renal size continued to increase. In January 1997, he was admitted to our hospital with abdominal distension and anorexia, in addition to progression of anemia. Upper gastroendoscopy showed an esophageal ulcer and severe external compression of the stomach. Renal angiography using the Seldinger technique showed stretched and deformed segmental renal arteries with massive enlargement of the kidneys. TAE with stainless steel coils was performed on both renal arteries. With a rapid and progressive decrease in kidney size, anorexia and anemia were improved, and the gastrointestinal compression was eliminated. In some patients with ADPKD, renal size continues to increase even after the initiation of dialysis. In about 10 years, patients develop gastrointestinal complications, such as dysphagia, ileus, severe constipation, and intestinal perforation. Surgical procedures such as nephrectomy are not satisfactory. This report shows that TAE is a safe and effective therapy for patients with ADPKD with massively enlarged kidneys.
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PMID:Transcatheter renal arterial embolization therapy on a patient with polycystic kidney disease on hemodialysis. 1056 Nov 51

An 81-year-old gentleman with congenital polycystic kidney disease presented to his primary care physician with dysphagia, gastroesophageal reflux refractory to medical management, and 11.25 kg weight loss in a 6 mo-period. A barium swallow misdiagnosed a paraesophageal hernia for a Bochdalek hernia. Herein, we highlight how a Bochdalek hernia may be disregarded in the differential diagnosis and how providers can resort to a more common diagnosis, a paraesophageal hernia, which is more frequently encountered in old age and whose radiologic appearance might mimic a Bochdalek hernia.
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PMID:An 81-year-old gentleman with symptomatic Bochdalek hernia. 2389 90