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Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The presented analysis of a patient treated at the 1st Surgical Department of the Teaching Hospital in Bratislava meets the criteria for being classified as primary adenocarcinoma of the esophagus, whose characteristics are described in the paper. Primary adenocarcinomas of the esophagus occur rarely and constitute only about 0.5% of large series of esophageal malignancies. The tumor is not connected with the gastric mucosa, being separated from it by the normal mucosa of the esophagus, and it is not a metastasis. The patients suffer from late not marked dysphagia. The endoscopic and histologic findings are frequently misleading since the mucosa above the tumor is usually intact.
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PMID:[Primary adenocarcinoma of the esophagus]. 220 37

The case series of a population-based case-control study of laryngeal and hypopharyngeal cancers in Torino, Italy, included 281 men with clinical and anamnestic data. Two hundred fifteen, 28, and 38 cancers originated from the endolarynx, epilarynx, and hypopharynx, respectively. Regions invaded by the tumor were divided into 26 subsites. A classification based on the number of invaded subsites was proposed, which agreed well with the T classification of the TNM system. Cancers originating from the hypopharynx invaded more subsites than cancers from the endolarynx, and among the latter, supraglottic were more invasive than glottic lesions. The number of invaded subsites was strongly associated with nodal involvement. Among symptoms at onset of disease and at diagnosis, patients with endolaryngeal lesions reported dysphonia and dyspnea more frequently, and patients with lesions from other regions had a higher prevalence of dysphagia, odynophagia, otalgia, and adenopathia. Clinical and epidemiologic results of this study suggest considering the endolarynx, epilarynx, and hypopharynx as separate anatomic entities. Diagnostic delay was not associated with tumor size and showed a negative trend with involvement of cervical lymph nodes, suggesting that stage at diagnosis is due to intrinsic differences in tumor aggressiveness.
Cancer 1990 Oct 15
PMID:Topographic classification, clinical characteristics, and diagnostic delay of cancer of the larynx/hypopharynx in Torino, Italy. 220 25

Nutrition plays an important role in health and disease, both in prevention and treatment. Increasing emphasis is being placed upon nutrition as a therapeutic tool to decrease the morbidity and mortality associated with obesity, hypertension, coronary artery disease, and cancer. Adequate nutrition should be a concern for all health care workers because of its impact on the overall health of patients. Health care professionals should be familiar with the essentials of nutritional assessment and basic nutritional requirements and be able to improve their patients' care in the face of nutritional deficiencies or excesses.
Dysphagia 1990
PMID:Nutritional assessment and requirements. 220 96

A case of thoracic duct cyst was reported. The patient, 72 year old man, was admitted with chief complaint of dysphagia. Chest X-ray film demonstrated an ovoid mass at the right upper mediastinum and the esophagus pressed by the tumor to the right. CT scan showed a round tumor with obscure margin located at the right upper mediastinum. Other laboratory data were almost within normal limits. Thoracotomy was performed on March 26, 1987 under diagnosis of leiomyoma of the esophagus. A fluid containing cyst covered with pleura was found at the upper mediastinum. The tumor was connected to the thoracic duct at its upper and lower portion. The cyst was isolated by sharp and blunt dissection without difficulties and removed. The cyst measured 7.5 X 4.5 X 4.5 cm and contained chyle. Pathological examination revealed no evidence of malignancy. Postoperative course of this patient was uneventful, and dysphagia was disappeared.
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PMID:[Thoracic duct cyst--a case report]. 221 86

Over the next several decades the gastroenterologist practicing anywhere in the world will be confronted with patients with AIDS-related gastrointestinal disorders. Universal body substance isolation precautions should be practiced, however, in dealing with all patients, including those outside traditional 'risk' groups for AIDS. Principal among these precautions are using gloves for personnel involved in procedures and high-level disinfection or sterilization for all endoscopy equipment. Endoscopic procedures should be planned well in advance with special attention to endoscope selection and transport media availability. Organ-associated symptoms are reviewed, especially dysphagia, odynophagia, hemorrhage, diarrhea, and abdominal pain. Opportunistic infections and malignancies often present characteristic endoscopic appearances such as that seen for cytomegalovirus ulceration or Kaposi's sarcoma. AIDS-related biliary disorders should also be recognized, principally sclerosing cholangitic or papillary stenosis.
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PMID:AIDS and the gastroenterologist. 223 76

Secondary esophageal achalasia due to malignancy is a rare condition; only 53 such cases have been reported to date. Sixty-two percent of the cases were due to gastric adenocarcinoma. Mesothelioma of the peritoneum is an uncommon neoplasm. The usual presenting symptoms are abdominal pain, abdominal mass, or abdominal distention. The patient we are reporting had peritoneal mesothelioma which presented with dysphagia and weight loss, in addition to the radiological and manometric picture of achalasia. Secondary achalasia was suspected clinically, and was confirmed by computed tomography and laparotomy. The diagnosis of peritoneal mesothelioma was made only by histopathological examination. We are not aware of any other report documenting the association of peritoneal mesothelioma and achalasia.
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PMID:Peritoneal mesothelioma: an unusual cause of esophageal achalasia. 225 28

Fifty-three cases with moderate or advanced esophageal and cardiac cancer treated by endoscopic microwave therapy are reported. The results showed that after 2 to 4 treatments, dysphagia was relieved in 52 (98%), esophageal re-expansion was seen in 48 (90%). Improvement was most pronounced in lesions predominantly shown as localized polypoid projection type. Biopsy after treatment was confirmed pathologically as necrosis in 24 cases. After treatment, the follow-up of 22 cases for over 3 months and 8 cases for over 6 months was carried out. 22/22 could maintain the therapeutic effectiveness and 5/8 were on soft diet (noodles and steamed bread). Microwave therapy is a palliative measure that can definitely improve the dysphagia in short term courses and prolong the survival. Microwave endoscopy, being easy in manipulation without complications, is very useful in the treatment of esophageal and cardiac cancers contra-indicated for surgery.
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PMID:[Endoscopic microwave treatment of 53 cases with esophageal and cardiac cancer]. 227 34

An unusual case of gastric carcinoma with diffuse intrasinusoidal metastasis to the liver (DIML) presenting as fulminant hepatic failure is reported. The patient was a 59-year-old man admitted to the hospital complaining of dysphagia. Seven weeks after performance of total gastrectomy, he developed jaundice and consciousness disturbance and died 4 days later. The surgical material was diagnosed as advanced cancer (poorly differentiated adenocarcinoma) of the stomach and postmortem examination disclosed massive and diffuse infiltration of the tumor cells into the hepatic sinusoids with no grossly detectable metastatic nodules. It is important to be aware that, although uncommon, gastric carcinomas may cause fulminant hepatic failure attributable to DIML. The clinicopathologic features of such cases are detailed and a review of the relevant literature included.
Cancer 1990 Jan 01
PMID:Diffuse intrasinusoidal metastasis of gastric carcinoma to the liver leading to fulminant hepatic failure. A case report. 229 61

The paper discusses application of endoscopic electrothermocoagulation in complex treatment of inoperable cancer of the esophagus and the proximal part of the stomach presenting with severe dysphagia. The study included 247 such patients, with 77.3% having stage IV tumor. 202 cases underwent electrothermocoagulation as a component of the treatment modality whereas 45 received standard therapy (controls). The newly-developed procedure assured enteral nutrition in 95.4% of cases and a drop in treatment--related complication rate from 33 to 9.3%. Survival ranged 8.4-11.2 months in different study groups and was as low as 3.1 months in controls.
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PMID:[Endoscopic electrothermocoagulation of tumors in inoperable cancer of the esophagus and proximal part of the stomach]. 230 67

Between 1978 and 1988, 88 patients were referred for the surgical treatment of nonmalignant Barrett's esophagus. Nineteen patients required esophageal resection. Male/female ratio was 13:6; age range was 13 to 84 years (mean age, 49.8 years; median age, 40 years). Preoperative studies demonstrated strictures in 11 patients and ulcers in 7. Penetrating Barrett's ulcer resistant to treatment was the indication for resection in 5 patients. Ulcers penetrated to the pericardium (1 patient), pulmonary vein (1), lung (1), and mediastinum (2). Other indications for resection included undilatable strictures (2), previous operations (4), high-grade dysplasia (3), parietal cells lining the esophagus (1), patient's refusal of long-term surveillance (2), and the inability to exclude adenocarcinoma preoperatively (2). Reconstruction was achieved by colon interposition (15) or esophagogastrostomy (4), with one postoperative death. Mean follow-up was 41 months and was 100% complete. Of the 18 patients, 3 have occasional regurgitation but none have any dysphagia or weight loss. Esophageal resection is indicated in a select group of patients with Barrett's esophagus. Absolute indications include a deep penetrating ulcer confirmed intraoperatively, high-grade dysplasia, strong suspicion of cancer, and multiple previous operations. Relative indications include strictures not responding to dilation and young patients refusing long-term surveillance.
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PMID:Indications for esophagectomy in nonmalignant Barrett's esophagus: a 10-year experience. 228 18


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