Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011168 (dysphagia)
 15,644 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 19-year-old Negro female, gravida 2, para 1, was presented at the Queen Elizabeth Hospital in Barbados, West Indies with difficulty opening her mouth; bleeding, and spasms of the skeletal muscles. A week before, she had undergone an illegal abortion performed by a friend. Curettage; tracheostomy; and passage of a nasogastric tube under general anesthesia were performed after admission. Antitetanus serus; high doses of diazepam; promazine for sedation; and antibiotics were administered. Curarization; assisted ventilation; and maintenance of nutrition through parental fluids were observed. Bilateral pneumothorax; tachycardia; and hypotension complicated the patient's course. The patient was discharged on the 40th day of hospitalization and was advised to visit the medical and gynecology clinic for follow-up examination and completion of tetanus immunization. Factors critical in the management of postabortal tetanus patients include: 1) recognition of classical signs of trismus; risus sardonicus; dysphagia and increased muscular tone and spasms; 2) use of antitetanus serum after sensitivity testing; 3) antibiotic coverage for clostridia and anaerobic organisms; 4) tracheostomy; curarization and assisted ventilation where necessary; 5) continuous medical and nursing care in a quiet room; 6) adequate hydration and nutrition; 7) treatment of site of injury, and curettage where necessary; 8) hysterectomy where necessary; and 9) post treatment immunization.
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PMID:Post-abortal tetanus. 120 40

A complete search of the literature concerning Lyme borreliosis as it relates to horses and cattle was done. The epidemiology, pathogenesis, immunological response to the disease, diagnosis and treatment are discussed. A review of clinical cases in horses and cattle is presented. Clinical signs of Lyme borreliosis in horses include: chronic weight loss, sporadic lameness, laminitis, low grade fever, swollen joints, muscle tenderness, and anterior uveitis. In addition to those clinical signs, neurological signs such as depression, behavioral changes, dysphagia, head tilt and encephalitis can be seen in chronic cases. Borreliosis occurs in cattle, usually as a herd problem. In acute Lyme borreliosis, cattle often will show a fever, stiffness, swollen joints, and decreased milk production. Chronic weight loss, laminitis and abortion are also possible outcomes of borreliosis in cattle. Diagnosis of clinical Lyme borreliosis is difficult and depends upon recognition of clinical signs, a history of possible exposure, and identification of the spirochete in the affected animal. Since the spirochete is very difficult to culture, confirmation of B. burgdorferi infection often relies on serologic testing. Subclinical seropositive animals do occur, thus confusing the diagnosis. An approach to treatment of cattle and horses with Lyme borreliosis is outlined.
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PMID:Lyme borreliosis in cattle and horses: a review of the literature. 164 76

A case is reported of a 20-year-old married female who developed esophageal stricture following consumption of potassium permanganate as an abortifacient. The woman was admitted in May 1985 with progressive dysphagia of 4 weeks duration. A week before the onset of symptoms, she was given, by a "village quack", a powder to be taken with sugar for inducing abortion in the 1st trimester of pregnancy. Immediately after consuming about 25 g of this powder, the patient experienced intense pain in the retrosternal area. She vomited repeatedly the whole day and aborted 12 hours later. Soon thereafter, she began to have difficulty in swallowing, which increased progressively over the next month before she came to the hospital for advice. Examination revealed mild dehydration. The oral cavity did not show any ulceration. A barium swallow showed a long, narrow stricture of the esophagus. Endoscopy revealed a mild esophagitis from 20-24 cm, beyond which a long, narrow stricture could be seen. A feeding tube was put in, and 2 weeks later endoscopic dilatation with Eder-Puestow dilators was begun. She underwent 6 sittings of dilatation which led to complete recovery of her symptoms. A followup barium study was not done since the patient had conceived again. A sample of the "powder" which she had consumed was chemically analyzed and found to be potassium permanganate. This case illustrates that potassium permanganate (KMn04) can cause severe chemical burns to the esophagus, which on healing may reult in fibrosis leading to stricture formation.
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PMID:Potassium permanganate induced oesophageal stricture. 380 59

A study of literature concerning Lyme borreliosis related to animals was done. In the research work the epidemiology, pathogenesis, diagnosis and treatment of horses, cattle and dogs affected with Lyme borreliosis have been discussed. The clinical signs of Lyme borreliosis in horses are: chronic weight loss, sporadic lameness, laminitis, low grade fever, swollen joints, muscle tenderness and anterior uvetitis. In addition to these clinical sings, neurological sings such as depression, behavioral changes, dysphagia and encephalitis can be seen in chronic cases. Cattle affected with acute Lyme borreliosis often show fever, stiffness, swollen joints and decreased milk production. Chronic weight loss, laminitis and abortion are also a possible outcome of borreliosis in cattle. An early infection of Lyme borreliosis in dogs may give evidence of inapetenca, lethargy, lyphadenopathy, and an acute onset of stiffness or pain while a recurrent intermittent nonerosive arthritis is a more advanced manifestation of canine Lyme borreliosis. Glomerulonephritis and tubular damage secondary to Borrelia burgdorferi infection have been reported to occur in normally infected dogs. In an endemic area atrioventricular heart block has also been reported. The underlying pathogenesis of Lyme disease is still unknown. The diagnosis of clinical Lyme borreliosis is difficult and it depends on a successful recognition of clinical signs, a history of possible exposures to the infection and on serologic testings. The therapy of Lyme borreliosis in animals is based upon the principal therapy of this disease in human medicine.
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PMID:[The importance of Lyme borreliosis in veterinary medicine]. 826 22