Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011053 (deafness)
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Human Gene/Protein
protein phosphatase 2A regulatory subunit A beta isoform 11.6
PDZ domain containing 7 11.6
Succinate-CoA ligase, ADP-forming, beta subunit 11.6
MYO3A protein 11.6
chromosome 2 open reading frame 37 11.6
PAHX-AP 11.6
TMEM2 protein 11.6
COIII protein 11.6
ZFOC1 11.6
ADRACALIN 11.6
deafness locus associated putative guanine nucleotide exchange factor 11.6
COL11A2 protein 11.6
DELGEF 11.6
DFNB8 11.5
LRTOMT 11.4
DFNB9 11.3
DFNB3 11.2
CMTX5 11.1
Melnick-Fraser syndrome 11.0
DFNB31 11.0
WS2A 11.0
MYO15A 11.0
DFNA3 11.0
TMIE 10.9
DFNB23 10.9
Stereocilin 10.9
ELMOD3 10.9
TMPRSS3 10.8
mucolipin 3 10.8
TMC1 10.7
USH1F 10.7
CLRN2 10.6
LHFPL5 10.6
DFNB36 10.6
SERAC1 protein 10.6
Doublecortin domain-containing protein 2 10.6
TMEM164 10.6
Transmembrane channel-like protein 1 10.6
DMXL2 protein 10.6
Otoancorin 10.6
more...
Disease
CORD9 11.6
DFNB46 11.6
DFNB20 11.6
DFNB27 11.6
WS2-OA 11.6
Cranial nerve compression 11.6
ATS-DL 11.6
DFNB15 11.6
Cerebellopontine angle meningioma 11.6
unilateral partial deafness 11.6
AUNA1 11.6
Syndromal deafness 11.6
4p minus syndrome 11.6
Apallic syndrome 11.6
CMTX4 11.6
DFNB65 11.6
Central deafness 11.6
DFNB26 11.6
AUNX1 11.6
deafness 11.6
Neonatal hearing loss 11.6
NPHP1, DEL 11.6
Circumscribed labyrinthitis 11.6
DFNA18 11.6
Cortical deafness 11.6
Neonatal conjugated hyperbilirubinemia 11.6
X-linked recessive agammaglobulinemia 11.6
Vestibular nerve disorder 11.6
DFNB5 11.6
eustachian tube catarrh 11.6
DFNB40 11.6
Acquired Deafness 11.6
DFNB10 11.6
CSNB2A 11.6
Congenital dysphasia 11.6
DFNA16 11.6
DFNB51 11.6
Deafness 11.5
DFNB18 11.5
DFNB8 11.5
more...
Symptom
Sudden deafness 11.2
Hearing complaints 10.0
Bruns nystagmus 9.6
dysacusis 8.6
diminished hearing 8.5
Tandem gait 8.3
unable to hear 8.3
Subjective tinnitus 8.1
External ophthalmoplegia 7.8
Noise-induced hearing loss 7.4
tinnitus 7.4
Circling 7.2
vertigo 7.1
dyslalia 7.1
parosmia 7.0
delayed language development 6.8
sinus pain 6.7
hyperacusis 6.7
Spontaneous nystagmus 6.6
otalgia 6.6
staggering gait 6.5
catarrh 6.3
aprosodia 6.2
cerebellar ataxia 6.2
athetosis 6.1
anosmia 6.1
loss of equilibrium 6.1
Kernig's sign 6.0
koilonychia 6.0
ophthalmoplegia 5.9
Beau's lines 5.9
loss of taste 5.9
monoplegia 5.8
pressure in the ear 5.8
General symptoms 5.7
ataxia 5.7
ENT 5.6
Bell's phenomenon 5.6
facial droop 5.6
painful swallowing 5.6
more...
Drug
Serc 10.0
Kanamycin sulfate 8.8
Dolobid 8.8
Kallidinogenase 8.1
Alsterpaullone 8.0
Mecobalamin 7.9
Meclomen 7.0
Isoxicam 6.6
Meclomen 6.6
Tirapazamine 6.1
Zinc acetate 6.0
Benzofuran 6.0
Calcium gluconate 6.0
Zmax 5.9
LVFX 5.7
PAPM/BP 5.7
Fenoprofen 5.7
Batroxobin 5.6
Naftidrofuryl 5.4
Naprosyn 5.4
Trental 5.3
Hakka 5.3
ENT 4.9
Mectizan 4.9
Salicylate 4.8
Cinnarizine 4.8
Idebenone 4.7
Acitretin 4.4
Lead acetate 4.3
Beta-2 4.2
AVC 4.1
Deferasirox 4.0
Fansidar 3.7
Azithromycin 3.7
Fansidar 3.6
Anakinra 3.6
Magnesium sulfate 3.6
Mezlocillin 3.5
DBS 3.4
IPD 3.4
more...
Enzyme
nucleotide 3'-pyrophosphokinase 8.1
HDR 7.6
proteasome ATPase 7.6
thiamine pyrophosphokinase 7.3
dihydroxyacetone phosphate acyltransferase 6.8
2-oxoglutarate decarboxylase 6.7
spermine synthase 6.4
Lod 6.3
chondroitin 6-sulfotransferase 6.2
ornithine cyclodeaminase 6.2
chondroitin synthase 6.2
dihydroxyacetone-phosphate acyltransferase 6.0
GM3 synthase 5.9
biotinidase 5.8
PRPP synthetase 5.7
calpain 10 5.6
lysyl-tRNA synthetase 5.5
factor C 5.1
seryl-tRNA synthetase 4.9
ceramide kinase 4.8
spermidine synthase 4.8
GalNAc-T 4.8
alpha-methylacyl-CoA racemase 4.8
CYP7B1 4.6
tRNase Z 4.6
guanidinoacetate methyltransferase 4.5
CTD kinase 4.5
hepsin 4.4
hepsin 4.4
jararhagin 4.3
phenylalanyl-tRNA synthetase 4.1
adenylosuccinate lyase 4.0
PTA 4.0
histidyl-tRNA synthetase 4.0
succinyl-CoA synthetase 3.9
amylomaltase 3.9
pyridoxal kinase 3.8
NPL 3.8
methylthioadenosine phosphorylase 3.7
histidase 3.7
more...
Compound
(2-aminophenyl)methanol 11.6
1-alkenyl-2-acyl-glycerophosphoethanolamine 10.6
C7H9NO 9.6
BAHA 8.8
Kanamycin sulfate 8.6
Chloramphenicol sodium succinate 8.6
Complamin 8.6
2-butenenitrile 8.5
A 435 8.4
bromic acid 8.0
Linopirdine 7.9
3-butenenitrile 7.7
Meclofenamate sodium 7.6
Praxilene 7.6
Streptomycin sulfate 7.4
Ronicol 7.3
reduced riboflavin 7.0
Ronicol 7.0
Tiludronate 6.7
Centrophenoxine 6.5
Betahistine 6.4
Ajmalicine 6.3
Methylxanthine 6.2
Papaverine hydrochloride 6.2
Salicin 6.2
Salicin 6.2
Closantel 5.9
Fenoprofen 5.9
Zinc acetate 5.8
heme O 5.6
Thiamine 5.4
Halofantrine 5.4
HEI 5.4
Azoxymethane 5.2
Methylcobalamin 5.2
TETA 5.2
SSD 5.2
ENU 5.2
1,2,4-benzotriazine 5.0
Tanakan 4.9
more...