Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0010346 (Crohn's disease)
 21,615 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
C22orf34 10.5
OR5V1 10.5
DDXL 10.5
ubiquitination factor E4A 10.5
SF3B14 10.5
defensin, beta 4 10.5
tubulin, beta 1 10.5
P450-CYP21B 10.5
Glyoxylate reductase/hydroxypyruvate reductase 10.5
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 10.5
IBD1 10.3
caspase recruitment domain-containing protein 15 10.1
CARD15 10.0
SP140 protein 9.9
IRGM 9.9
Cytochrome P450 4F3 9.5
HLA-Bw62 antigen 9.5
contactin associated protein-like 3 9.5
HEATR3 9.5
HNRPH3 9.5
butyrophilin protein 9.5
ZNF713 9.5
YDJC 9.5
KID2 9.5
HNRPAB 9.5
SPP24 9.5
NOD2 protein 9.4
DLG5 9.4
IBD2 9.4
NKX2-3 9.2
C13orf31 9.2
FAM92B 9.2
ATG16L1 9.1
NOD2 9.0
DEFA6 9.0
MAP3K7IP1 8.9
TCERG1L 8.9
RAVER2 8.9
TMEM183A 8.9
HEBP1 8.9
RAB2A, member RAS oncogene family 8.9
Erbb2 interacting protein 8.9
CCDC88B 8.9
zymogen granule membrane glycoprotein 2 8.9
SP140L 8.9
CUZD1 8.9
IFRD2 8.9
IL10 protein 8.9
IBD 8.9
ICOSLG 8.8
nucleotide-binding oligomerization domain 2 8.8
alpha-4 integrin 8.8
MLCK protein 8.8
EHBP1L1 8.7
PSMG1 8.7
PPP2R3B 8.5
SEEK1 8.5
Defensin-5 8.5
FRMPD2 8.5
PFM2 8.5
REG III 8.5
neural epidermal growth factor-like 1 8.5
SDCCAG3 8.5
RNF186 8.5
nuclear receptor binding factor 2 8.5
IL23R 8.5
nucleotide-binding oligomerization domain containing 2 8.4
TMEM59 8.4
DLT 8.4
C1orf106 8.4
ATG16L 8.3
CCDC122 8.2
lacking exon 14 8.2
PUS10 8.2
ABHD3 8.2
transmembrane protein 59 8.2
LZTR-1 8.2
FBXL12 8.2
calmodulin binding transcription activator 1 8.2
DNAJB5 8.2
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Disease
Anorectal cancer 10.5
Crohn's duodenitis 10.5
IBD9 10.5
Infective proctitis 10.5
Isolated granulomatous gastritis 10.5
Crohn's disease 10.5
Juvenile polyp 10.5
Ulcerative proctosigmoiditis 10.5
IBD3 10.5
Crohn's proctitis 10.5
IBD8 10.5
Gastrointestinal inflammatory conditions 10.5
Ulcerative jejunitis 10.5
Duodenal Crohn's disease 10.5
IBD7 10.5
Follicular occlusion triad 10.5
Vulval Crohn's disease 10.5
Diverticulosis of the ileum 10.5
Chlamydial proctitis 10.5
Contact cheilitis 10.5
Crohn's disease of terminal ileum 10.5
Mesalazine allergy 10.5
IBD5 10.4
Perianal Crohn's disease 10.1
Crohn's ileocolitis 10.1
Crohn's ileitis 10.0
IBD6 9.9
Orofacial granulomatosis 9.9
IBD4 9.9
Parastomal pyoderma gangrenosum 9.9
Crohn's esophagitis 9.9
IBD2 9.8
ileocolitis 9.8
Indeterminate colitis 9.7
Crohn's colitis 9.7
Neonatal neutropenia 9.5
Acute uveitis 9.5
Granulomatous gastritis 9.5
Acute ulcerative colitis 9.5
Toxic colitis 9.5
Food sensitivity 9.5
Hamel syndrome 9.5
Iliac vein thrombosis 9.5
salmonella colitis 9.5
Anal furunculosis 9.5
Pseudopolyposis 9.5
Intestinal ulceration 9.5
Nutritional and Metabolic Diseases 9.5
Reactive gastropathy 9.5
ulcerative colitis 9.4
Inflammatory Bowel Disease 9.4
Terminal ileitis 9.3
Cheilitis granulomatosa 9.3
Allergic colitis 9.3
ileitis 9.2
Enteropathic arthritis 9.2
Duodenocolic fistula 9.2
regional enteritis 9.0
idiopathic proctocolitis 9.0
Witts 9.0
Crohn's jejunitis 8.9
hypercalcaemia due to parathyroid adenoma 8.9
Intestinal GVHD 8.9
Acute proctitis 8.9
intestinal tuberculosis 8.9
Pancolitis 8.8
Pyoderma vegetans 8.8
inflammatory bowel disease 8.8
Pyostomatitis vegetans 8.7
Gastrointestinal inflammation 8.7
Mucosal prolapse syndrome 8.5
Duodenal disease 8.5
Crohn's gastritis 8.5
PFM2 8.5
Acute alveolitis 8.5
campylobacter colitis 8.5
Pericholangitis 8.5
Abdominal wall abscess 8.5
small bowel adenocarcinoma 8.5
Toxic megacolon 8.4
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Symptom
Psoas sign 10.5
Perianal pain 9.5
Remittent fever 8.9
bilateral carotid bruits 8.5
Vulval pain 8.5
pneumaturia 8.3
inflammation of the vulva 7.9
Portal venous gas 7.5
GI pain 7.3
Chronic abdominal pain 7.0
Intermittent fever 6.8
Persistent vomiting 6.8
Frequency of defecation 6.6
Retrosternal pain 6.5
change in stool 6.3
anal pain 6.2
Upper abdominal pain 6.2
Cutaneous anergy 6.2
right lower quadrant pain 6.1
koilonychia 5.9
intestinal bleeding 5.8
Chronic pelvic pain syndrome 5.7
iliac fossa pain 5.6
generalized abdominal pain 5.5
swollen scrotum 5.5
painful swallowing 5.5
Watery diarrhea 5.4
Skin symptoms 5.4
rectal pain 5.3
Functional abdominal pain 5.0
vaginal pain 5.0
epigastric distress 4.9
Gastrointestinal symptoms 4.9
Livedoid 4.9
Amaurosis fugax 4.9
abdominal pain 4.9
colic 4.8
localized edema 4.8
non-productive cough 4.7
diarrhea 4.6
Murphy's sign 4.6
intestinal angina 4.4
generalized rash 4.4
abdominal cramps 4.3
Urinary symptoms 4.3
menometrorrhagia 4.2
clubbing 4.2
acute abdomen 4.1
Flare 4.1
Crawling 4.0
acute abdominal pain 3.9
hyperemesis 3.9
hypoproteinemia 3.8
bloating 3.8
Musculoskeletal symptoms 3.8
Cushingoid 3.8
dyschezia 3.7
Cushingoid 3.7
polymyalgia 3.7
pleuritic chest pain 3.6
tenesmus 3.6
stomach pain 3.6
Wind 3.6
periorbital edema 3.5
epigastric pain 3.5
left upper quadrant pain 3.5
vestibulitis 3.5
abdominal discomfort 3.5
dark urine 3.4
lassitude 3.4
arthralgia 3.4
decreased appetite 3.3
urethral discharge 3.3
night sweats 3.3
constipation 3.3
Severe pain 3.2
precordial pain 3.1
hyperesthesia 3.1
pachyonychia 3.0
jaw pain 3.0
more...
Drug
Entocort EC 10.5
Tenovil 10.5
Fontolizumab 10.5
Onercept 9.5
Debromohymenialdisine 9.5
Certolizumab pegol 9.1
Infliximab 9.0
Infliximab 9.0
Enterued 8.9
Mesalazine 8.8
Dipentum 8.5
Adalimumab 8.3
Teduglutide 8.0
Mercaptopurine 7.8
Sulphasalazine 7.3
Natalizumab 7.2
Tixocortol pivalate 6.9
Budesonide 6.8
Rifaximin 6.6
Golimumab 6.5
Elmiron 6.4
Pentosan polysulfate sodium 6.2
Dextran sulfate sodium 6.1
Efalizumab 5.7
Efalizumab 5.7
Imodium 5.6
Adenosine Monophosphate 5.6
Alefacept 5.3
Imodium 5.2
Novantrone 5.2
Prolastin 5.2
Cilomilast 5.1
Somatropin 5.0
Alfacalcidol 5.0
Ethylcellulose 4.9
Lumiracoxib 4.9
Prednisone 4.9
Synthroid 4.9
IL-11 4.8
Tocilizumab 4.8
Barium sulfate 4.7
Fluticasone propionate 4.7
CED 4.7
Folic Acid 4.5
OctreoScan 4.5
Fosamax 4.4
Carbadox 4.3
Anakinra 4.1
CDX 4.1
Synthroid 4.1
Levovist 4.1
Valganciclovir 4.0
Zinc sulfate 4.0
Zinc sulfate 4.0
Mizoribine 3.9
Abatacept 3.9
Malonaldehyde 3.9
Gastro 3.9
Serum albumin 3.8
Prednisolone 3.8
Liposyn 3.7
CDX 3.7
Pirfenidone 3.6
CDP 3.6
Propidium 3.5
Cobalamin 3.5
Orphan 3.5
IL-1ra 3.4
Xanthium 3.4
Avonex 3.4
p75 3.4
Vinpocetine 3.3
Methylprednisolone 3.3
Hypaque 3.3
Vitamin B12 3.2
Mirtazapine 3.2
Nitazoxanide 3.2
KGF 3.2
Calcipotriol 3.2
Opium 3.1
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Enzyme
hippurate hydrolase 7.9
D-2-hydroxy acid dehydrogenase 7.5
4-N-trimethylaminobutyraldehyde dehydrogenase 7.4
thiopurine methyltransferase 7.0
matrilysin-2 6.2
EC 3.4.19.1 6.1
LTB4 omega-hydroxylase 5.8
CobT 5.8
acetate CoA-transferase 5.3
cholesterol 25-hydroxylase 5.0
proteinase-3 4.9
BBE 4.8
AICAR transformylase 4.7
enzyme X 4.7
carboxypeptidase D 4.6
caspase-5 4.3
amylo-1,6-glucosidase 4.2
butyrate kinase 4.1
caspase-5 4.0
matriptase 4.0
lactase 3.9
ceramide kinase 3.8
alpha-methylacyl-CoA racemase 3.7
polyphosphatase 3.7
peptidylarginine deiminase 3.6
bile salt hydrolase 3.6
matriptase 3.6
HOA 3.5
diol dehydratase 3.4
macrophage elastase 3.4
prostasin 3.3
lipoate acetyltransferase 3.3
FADS 3.3
NPL 3.3
deoxyhypusine synthase 3.2
inosine triphosphatase 3.2
lactase-phlorizin hydrolase 3.2
oxoglutarate dehydrogenase 3.2
sucrase-isomaltase 3.1
myosin light chain kinase 3.0
azoreductase 3.0
3alpha-hydroxysteroid dehydrogenase 3.0
histamine N-methyltransferase 3.0
histidyl-tRNA synthetase 3.0
kynureninase 3.0
neutrophil collagenase 2.9
mevalonate kinase 2.9
dextranase 2.9
lactase-phlorizin hydrolase 2.8
aminopeptidase A 2.8
AAE 2.8
lysophospholipase D 2.7
cathepsin G 2.7
methylthioadenosine phosphorylase 2.7
caspase-1 2.7
endo-N 2.6
indoleamine 2,3-dioxygenase 2.6
MDP 2.6
alpha-L-fucosidase 2.6
alpha-L-fucosidase 2.6
thrombin-activatable fibrinolysis inhibitor 2.6
C3b inactivator 2.5
alpha-L-fucosidase 2.5
chymase 2.5
LPL 2.4
meprin 2.4
MMP-3 2.4
granzyme B 2.3
sucrase 2.3
LTA4 hydrolase 2.3
dimethylarginine dimethylaminohydrolase 2.3
diamine oxidase 2.3
tryptase 2.3
hyaluronate lyase 2.2
tissue kallikrein 2.2
UDP-glucose dehydrogenase 2.2
CPM 2.1
neutrophil elastase 2.1
paraoxonase 2.1
SMP 2.1
more...
Compound
Mesalamine 8.5
Neu5,7Ac2 7.9
Sulfasalazine 7.8
2,3-heptanedione 7.5
Allyl methyl disulfide 7.5
Azathioprine 7.2
Wander 7.2
Trinitrobenzenesulfonic acid 7.2
4-methylbenzamide 7.2
6-Mercaptopurine 7.1
Butin 6.9
Eusolex 6.8
Eriocitrin 6.7
Pinane 6.6
Etanercept 6.5
Olsalazine 6.4
Sulfapyridine 6.1
Pheniramine 6.1
TNB 5.9
1,3-Dinitrobenzene 5.8
Docosapentaenoic acid 5.8
Tamibarotene 5.7
Elan 5.6
6-Thioguanine 5.5
2,3-hexanedione 5.4
Lactulose 5.3
Elan 5.3
ANCA 5.3
Bismuth subsalicylate 5.2
20-OH-LTB4 5.2
dIMP 5.1
Azoxymethane 5.1
Lanthionine 5.0
20-COOH-LTB4 5.0
CD 3 5.0
Helenalin 5.0
SC-58125 4.9
PTMA 4.9
Oxamate 4.9
Phthalimide 4.9
DSS 4.9
Betanin 4.9
Benzathine 4.9
Glycocholic acid 4.8
Tumor Necrosis Factor 4.8
Ornidazole 4.7
barium 4.7
Beclomethasone 4.7
2-TCA 4.7
Palmatine 4.6
Mycophenolate mofetil 4.6
Loperamide 4.6
Wellcome 4.5
Fibrinopeptide A 4.5
Rifamycin 4.4
Azure A 4.4
TNF 4.4
Quercitrin 4.4
Zinc chloride 4.4
Syringic acid 4.4
Florid 4.4
Parks 4.3
Parenteral 4.3
Prednisone 4.2
Rifamycin 4.2
ASA 4.1
LTB5 4.1
TMF 4.1
Rifamycin 4.1
Fusidic acid 4.1
Deoxypyridinoline 4.0
Beauvericin 4.0
Neo 4.0
(S)-4-carboxyphenylglycine 4.0
Methotrexate 3.9
Zinc sulfate 3.9
Phenylhydrazine 3.9
CDP 3.9
Clofazimine 3.8
Auramine 3.8
more...