Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0010346 (Crohn's disease)
21,615 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein gut 1581 Sep 1380 cytokine 1144 TNF 896 tumor necrosis factor 803 IBD 543 NOD2 467 Mol 409 TNF-alpha 348 lymphoid 319 ankylosing spondylitis 316 C-reactive protein 306 IL-6 305 CD4 296 IL-10 283 IgA 249 She 245 CARD15 240 IL-17 200 ASA 180 HLA 171 IL-23 166 interferon 161 MRI 160 albumin 158 IL-8 155 IFN 152 collagen 151 tumor necrosis factor alpha 148 IFN-gamma 143 lipopolysaccharide 142 serum albumin 138 myeloperoxidase 121 ATG16L1 119 IL-4 118 CD8 116 Tumor necrosis factor 111 chemokine 108 interferon-gamma 105 TLR4 104 IL-1 97 interleukin-6 89 DLT 86 IL-2 85 LPS 84 CRP 83 granulocyte 83 glycoprotein 82 insulin 80 reserved 76 Cytokine 75 mucin 74 IgE 74 IRGM 73 p40 73 Pol 72 lactoferrin 70 B12 69 IL23R 69 hemoglobin 68 major histocompatibility complex 67 HLA-B27 66 IL-18 65 STAT3 65 CD14 63 interleukin-10 63 IL-22 62 lysozyme 62 inducible nitric oxide synthase 60 HLA-DR 59 IL-13 59 adhesion molecule 58 TNF receptor 58 alkaline phosphatase 57 defensin 57 p38 54 ESR 53 IL-5 52 MAPK 50 p53 50 more...

Disease Crohn's disease 21615 ulcerative colitis 7708 inflammatory bowel disease 6899 colitis 2301 cancer 1266 rheumatoid arthritis 1101 irritable bowel syndrome 802 psoriasis 581 tumor 531 celiac disease 498 tuberculosis 486 Mycobacterium 475 colorectal cancer 452 enteropathy 445 carcinoma 430 arthritis 412 Colitis 370 multiple sclerosis 368 systemic lupus erythematosus 359 bowel obstruction 357 ileitis 341 ankylosing spondylitis 333 sepsis 304 sarcoidosis 304 diabetes 298 malabsorption 298 sepsis 288 adenocarcinoma 277 malnutrition 268 Crohn's colitis 265 dysplasia 265 lymphoma 260 Colon 246 Colon 246 Colon 246 psoriatic arthritis 226 vasculitis 216 colon cancer 215 anemia 203 autoimmune disease 201 asthma 199 Johne's disease 192 diverticulitis 180 Inflammatory Bowel Disease 174 Rectum 168 Rectum 168 Rectum 168 Rectum 168 enteritis 167 primary sclerosing cholangitis 166 pyoderma gangrenosum 160 appendicitis 147 depression 145 osteoporosis 144 infectious diseases 142 short bowel syndrome 140 proctitis 139 regional enteritis 136 obesity 136 lupus 135 pancreatitis 134 uveitis 129 gastrointestinal disease 129 ileocolitis 128 immunodeficiency 126 chronic disease 124 erythema nodosum 123 type 1 diabetes 120 lupus 117 diverticular disease 115 hepatitis 112 cirrhosis 112 graft-versus-host disease 111 HIV 111 Best 110 familial adenomatous polyposis 108 polyposis 106 gastritis 105 ischemia 105 enterocolitis 104 more...

Symptom diarrhea 956 abdominal pain 614 pain 307 vomiting 120 nausea 93 fatigue 87 anesthesia 72 constipation 67 erythema 62 colic 60 discomfort 58 headache 58 discomfort 56 anorexia 55 arthralgia 50 weakness 44 cough 42 Ill 37 acute abdomen 37 dyspnea 36 seizures 31 intestinal bleeding 30 pneumaturia 29 epigastric pain 27 chest pain 27 splenomegaly 27 cachexia 24 Wind 21 back pain 20 acute abdominal pain 20 nausea and vomiting 20 starvation 19 shortness of breath 17 hepatomegaly 16 bloating 16 overweight 14 right lower quadrant pain 14 abdominal discomfort 13 angina 13 myalgia 13 respiratory distress 12 anal pain 12 tremor 12 Gastrointestinal symptoms 12 paresthesia 12 bone pain 11 chills 11 hypoproteinemia 11 dysuria 11 fever of unknown origin 11 clubbing 11 hepatosplenomegaly 10 collapse 10 low back pain 10 ataxia 9 sore throat 9 acidity 8 sleepiness 8 decreased appetite 8 lethargy 8 night sweats 8 alexithymia 8 heartburn 8 blurred vision 7 pelvic pain 7 spasm 7 analgesia 7 abdominal cramps 7 exhaustion 6 chronic constipation 6 thinning 6 stigma 6 neck pain 5 non-productive cough 5 pallor 5 hip pain 5 dizziness 5 Chronic abdominal pain 5 pleuritic chest pain 5 syncope 5 more...

Drug Infliximab 388 Infliximab 388 Dermatol 288 IFN-gamma 137 Adalimumab 110 IL-2 86 Mesalazine 71 Budesonide 48 CSF 47 Natalizumab 38 Bifidobacterium 34 lactose 30 p75 27 Monit 23 Certolizumab pegol 22 ascorbate 21 IL-11 21 MAP 20 Prednisone 20 ROS 19 CDP 19 Sulphasalazine 16 lysine 16 Rifaximin 14 Prednisolone 14 Asthma 13 Cardiovasc 13 Serum albumin 12 ROC 12 vitamin E 11 CED 10 IL-1ra 10 Albumin 9 Gastro 9 Gel 9 Hypaque 8 Glucagon 8 Vitamin B12 8 Leaf 8 Nephron 8 EPA 8 Indomethacin 8 G-CSF 8 Tocilizumab 8 Dial 8 Tacrolimus 7 ENT 7 ampicillin 7 niacin 7 Retinoic acid 6 Teduglutide 6 Xanthium 6 Hypaque 6 Methylprednisolone 6 Mercaptopurine 6 Golimumab 5 Growth hormone 5 Cimetidine 5 Novantrone 5 CTX 5 GEO 5 Dipentum 5 Cimetidine 5 Nitric Oxide 5 Growth hormone 5 Nephron 5 Efalizumab 4 Efalizumab 4 Lactose 4 Histamine 4 DNase I 4 Orphan 4 Vitamin A 4 Estrogens 4 Rituximab 4 ACT 4 Gefitinib 3 Isotretinoin 3 Dextran sulfate sodium 3 Anakinra 3 more...

Enzyme peroxidase 143 mitogen-activated protein kinase 117 focal adhesion kinase 63 lysozyme 62 alkaline phosphatase 57 thiopurine methyltransferase 48 ERK 46 APC 32 superoxide dismutase 31 collagenase 28 caspase-1 27 reverse transcriptase 26 elastase 25 luciferase 24 glutathione peroxidase 23 lactase 22 caspase-3 22 phospholipase A2 21 trypsin 20 catalase 20 protein kinase 20 calcineurin 19 alanine aminotransferase 18 MAP 18 protein kinase C 17 NADPH oxidase 16 P-glycoprotein 16 NO synthase 16 aspartate aminotransferase 15 myosin light chain kinase 15 lipase 15 NADPH oxidase 13 thrombin 12 MMP-3 12 neutrophil elastase 12 proteasome 12 MDP 11 transglutaminase 11 IKK 11 granzyme B 11 MIP 10 ACE 10 creatine kinase 10 MMP 9 lactate dehydrogenase 9 tryptase 9 kallikrein 9 ACS 8 NOS 8 sucrase 8 phospholipase C 8 neuraminidase 8 arginase 8 diamine oxidase 8 phosphodiesterase 8 cathepsin G 8 cholinesterase 8 proteinase-3 7 tissue plasminogen activator 7 xanthine oxidase 7 RNA polymerase 7 endonuclease 7 phosphatidylinositol 3-kinase 7 ceruloplasmin 7 lipoxygenase 7 urokinase-type plasminogen activator 6 CYP3A4 6 chymotrypsin 6 caspase-8 6 MEK 6 urease 6 PARP 6 thromboplastin 6 acid phosphatase 6 urease 6 AST 6 ornithine decarboxylase 6 ATPase 6 indoleamine 2,3-dioxygenase 6 gamma-glutamyl transpeptidase 6 more...

Compound Clin 2365 Dec 1481 TNF 896 DNA 497 sodium 320 barium 288 sulfate 226 water 214 oxygen 192 ASA 186 calcium 169 vitamin D 158 iron 128 zinc 123 Azathioprine 104 leucine 92 nitric oxide 85 phosphate 83 His 83 glucose 80 nitrogen 77 Sulfasalazine 70 acetate 68 ethanol 62 creatinine 60 Methotrexate 51 PEG 51 DSS 50 potassium 50 NIDA 50 ANCA 49 Mesalamine 49 galactose 48 arginine 41 salt 40 tyrosine 39 6-Mercaptopurine 37 Etanercept 37 hydrogen 36 Neo 35 Vitamin D 35 serine 34 ATP 34 selenium 34 EDTA 33 EDTA 33 oxalate 33 Cyclosporine 32 Parenteral 32 Wellcome 32 glutamine 32 salicylic acid 30 copper 28 THP 26 THP 26 tryptophan 25 PEG 25 Optimal 25 GSH 25 GSH 25 cysteine 24 urea 23 Curcumin 22 tryptophan 22 alanine 22 tryptophan 21 SDS 21 retinoic acid 21 tryptophan 21 CO2 21 Phe 20 Cardiol 20 Prednisone 20 acetic acid 19 threonine 18 MAP 18 NADP 18 lysine 18 FK506 17 A 42 16 more...

---