Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0010346 (Crohn's disease)
 21,615 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ubiquitination factor E4A 10.5
DDXL 10.5
tubulin, beta 1 10.5
Glyoxylate reductase/hydroxypyruvate reductase 10.5
P450-CYP21B 10.5
defensin, beta 4 10.5
OR5V1 10.5
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 10.5
SF3B14 10.5
C22orf34 10.5
IBD1 10.3
caspase recruitment domain-containing protein 15 10.1
CARD15 10.0
SP140 protein 9.9
IRGM 9.9
butyrophilin protein 9.5
SPP24 9.5
YDJC 9.5
HEATR3 9.5
HNRPH3 9.5
KID2 9.5
Cytochrome P450 4F3 9.5
contactin associated protein-like 3 9.5
HLA-Bw62 antigen 9.5
HNRPAB 9.5
ZNF713 9.5
NOD2 protein 9.4
DLG5 9.4
IBD2 9.4
NKX2-3 9.2
FAM92B 9.2
C13orf31 9.2
ATG16L1 9.1
NOD2 9.0
DEFA6 9.0
TCERG1L 8.9
Erbb2 interacting protein 8.9
RAB2A, member RAS oncogene family 8.9
SP140L 8.9
TMEM183A 8.9
more...
Disease
Juvenile polyp 10.5
Gastrointestinal inflammatory conditions 10.5
Infective proctitis 10.5
Diverticulosis of the ileum 10.5
Duodenal Crohn's disease 10.5
IBD7 10.5
Follicular occlusion triad 10.5
Mesalazine allergy 10.5
IBD9 10.5
Ulcerative proctosigmoiditis 10.5
IBD3 10.5
Vulval Crohn's disease 10.5
Anorectal cancer 10.5
Crohn's disease of terminal ileum 10.5
IBD8 10.5
Chlamydial proctitis 10.5
Ulcerative jejunitis 10.5
Contact cheilitis 10.5
Isolated granulomatous gastritis 10.5
Crohn's disease 10.5
Crohn's proctitis 10.5
Crohn's duodenitis 10.5
IBD5 10.4
Perianal Crohn's disease 10.1
Crohn's ileocolitis 10.1
Crohn's ileitis 10.0
Crohn's esophagitis 9.9
IBD4 9.9
Orofacial granulomatosis 9.9
IBD6 9.9
Parastomal pyoderma gangrenosum 9.9
IBD2 9.8
ileocolitis 9.8
Indeterminate colitis 9.7
Crohn's colitis 9.7
Hamel syndrome 9.5
Granulomatous gastritis 9.5
salmonella colitis 9.5
Food sensitivity 9.5
Acute ulcerative colitis 9.5
more...
Symptom
Psoas sign 10.5
Perianal pain 9.5
Remittent fever 8.9
Vulval pain 8.5
bilateral carotid bruits 8.5
pneumaturia 8.3
inflammation of the vulva 7.9
Portal venous gas 7.5
GI pain 7.3
Chronic abdominal pain 7.0
Intermittent fever 6.8
Persistent vomiting 6.8
Frequency of defecation 6.6
Retrosternal pain 6.5
change in stool 6.3
anal pain 6.2
Upper abdominal pain 6.2
Cutaneous anergy 6.2
right lower quadrant pain 6.1
koilonychia 5.9
intestinal bleeding 5.8
Chronic pelvic pain syndrome 5.7
iliac fossa pain 5.6
generalized abdominal pain 5.5
swollen scrotum 5.5
painful swallowing 5.5
Watery diarrhea 5.4
Skin symptoms 5.4
rectal pain 5.3
Functional abdominal pain 5.0
vaginal pain 5.0
epigastric distress 4.9
Gastrointestinal symptoms 4.9
Livedoid 4.9
Amaurosis fugax 4.9
abdominal pain 4.9
colic 4.8
localized edema 4.8
non-productive cough 4.7
diarrhea 4.6
more...
Drug
Tenovil 10.5
Fontolizumab 10.5
Entocort EC 10.5
Onercept 9.5
Debromohymenialdisine 9.5
Certolizumab pegol 9.1
Infliximab 9.0
Infliximab 9.0
Enterued 8.9
Mesalazine 8.8
Dipentum 8.5
Adalimumab 8.3
Teduglutide 8.0
Mercaptopurine 7.8
Sulphasalazine 7.3
Natalizumab 7.2
Tixocortol pivalate 6.9
Budesonide 6.8
Rifaximin 6.6
Golimumab 6.5
Elmiron 6.4
Pentosan polysulfate sodium 6.2
Dextran sulfate sodium 6.1
Efalizumab 5.7
Efalizumab 5.7
Adenosine Monophosphate 5.6
Imodium 5.6
Alefacept 5.3
Imodium 5.2
Novantrone 5.2
Prolastin 5.2
Cilomilast 5.1
Somatropin 5.0
Alfacalcidol 5.0
Ethylcellulose 4.9
Lumiracoxib 4.9
Prednisone 4.9
Synthroid 4.9
IL-11 4.8
Tocilizumab 4.8
more...
Enzyme
hippurate hydrolase 7.9
D-2-hydroxy acid dehydrogenase 7.5
4-N-trimethylaminobutyraldehyde dehydrogenase 7.4
thiopurine methyltransferase 7.0
matrilysin-2 6.2
EC 3.4.19.1 6.1
LTB4 omega-hydroxylase 5.8
CobT 5.8
acetate CoA-transferase 5.3
cholesterol 25-hydroxylase 5.0
proteinase-3 4.9
BBE 4.8
AICAR transformylase 4.7
enzyme X 4.7
carboxypeptidase D 4.6
caspase-5 4.3
amylo-1,6-glucosidase 4.2
butyrate kinase 4.1
caspase-5 4.0
matriptase 4.0
lactase 3.9
ceramide kinase 3.8
polyphosphatase 3.7
alpha-methylacyl-CoA racemase 3.7
peptidylarginine deiminase 3.6
bile salt hydrolase 3.6
matriptase 3.6
HOA 3.5
diol dehydratase 3.4
macrophage elastase 3.4
prostasin 3.3
lipoate acetyltransferase 3.3
FADS 3.3
NPL 3.3
deoxyhypusine synthase 3.2
inosine triphosphatase 3.2
lactase-phlorizin hydrolase 3.2
oxoglutarate dehydrogenase 3.2
sucrase-isomaltase 3.1
myosin light chain kinase 3.0
more...
Compound
Mesalamine 8.5
Neu5,7Ac2 7.9
Sulfasalazine 7.8
2,3-heptanedione 7.5
Allyl methyl disulfide 7.5
Azathioprine 7.2
4-methylbenzamide 7.2
Wander 7.2
Trinitrobenzenesulfonic acid 7.2
6-Mercaptopurine 7.1
Butin 6.9
Eusolex 6.8
Eriocitrin 6.7
Pinane 6.6
Etanercept 6.5
Olsalazine 6.4
Sulfapyridine 6.1
Pheniramine 6.1
TNB 5.9
1,3-Dinitrobenzene 5.8
Docosapentaenoic acid 5.8
Tamibarotene 5.7
Elan 5.6
6-Thioguanine 5.5
2,3-hexanedione 5.4
Lactulose 5.3
Elan 5.3
ANCA 5.3
Bismuth subsalicylate 5.2
20-OH-LTB4 5.2
dIMP 5.1
Azoxymethane 5.1
20-COOH-LTB4 5.0
Lanthionine 5.0
CD 3 5.0
Helenalin 5.0
SC-58125 4.9
PTMA 4.9
Oxamate 4.9
Phthalimide 4.9
more...