Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010346 (Crohn's disease)
 21,615 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clostridium septicum (C. septicum) gas gangrene is well documented in the literature, typically in the setting of trauma or immunosuppression. In this paper, we report a unique case of spontaneous clostridial myonecrosis in a patient with Crohn's disease and sulfasalazine-induced neutropenia. The patient presented with left thigh pain, vomiting and diarrhea. Blood tests demonstrated a profound neutropenia, and magnetic resonance imaging of the thigh confirmed extensive myonecrosis. The patient underwent emergency hip disarticulation, followed by hemicolectomy. C. septicum was cultured from the blood. Following completion of antibiotic therapy, the patient developed myonecrosis of the right pectoral muscle necessitating further debridement, and remains on lifelong prophylactic antibiotic therapy.
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PMID:A case of gas gangrene in an immunosuppressed Crohn's patient. 2198 30

Ilio-psoas abscess due to right colon origin is rare and normally occurs secondary to Crohn's disease, diverticulitis or cancer. We report a case of a caecal tuberculosis (TB) presented initially with an appendicular mass and systemic symptoms of fever and fatigue and 3 weeks after, with right-sided anterior thigh pain and found to have an ilio-psoas abscess. Colonoscopy and histology confirmed the diagnosis of caecal-TB. She had a CT drainage of the abscess and was discharged with anti-TB treatment and her drain in situ. Repeat pelvic MRI 10 days after treatment showed the abscess resolving and her systemic symptoms improving.
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PMID:Right-sided colonic tuberculosis: a rare cause of ilio-psoas abscess. 2361 37