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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case report of pulmonary actinomycosis is presented. The 33-years old man complained of long term pain in the thorax, coughing and subfebrile body temperature. Pleural empyema and pulmonary neoplasm were suspected. The final diagnosis was established by open thoracotomy and definitive histological examination. Partial lung resection and post operative penicillin G therapy were performed.
Pneumonol Alergol Pol 2004
PMID:[Pulmonary actinomycosis]. 1575 75

Two cases of exogenous lipoid pneumonia are presented. The 22 years old woman was admitted to hospital because of recurrent dyspnea, cough, fever and chest pain, are changes on chest x-ray. Bronchoscopy, chest CT scan, respiratory functional test and laboratory tests were performed but the diagnosis was not established. Just before thoracoscopy patient revealed frequent intentionally choking with oil. The second patient 39 years old man was admitted because of dyspnea, cough, fever and chest pain, which appeared after accidentally choking with oil. In both cases the diagnosis was confirmed with special staining of bronchial discharge specimen.
Pneumonol Alergol Pol 2004
PMID:[Exogenous lipoid pneumonia]. 1575 76

The aim of the study was evaluation of the use of tracheostomy T-tube in patients with tracheal stenosis. The advantages of closed T-tube over open tracheotomy are: 1/ normal breathing through the nose, 2/ normal speech without necessity to close the tube with a finger, 3/ no spitting during cough. Silicone tracheostomy T-tube was used in 12 patients with tracheal stenosis. The stenosis resulted in 7 patients from prolonged intubation, in 4 patients from defective tracheostomy and in one patient from failure of tracheal resection. In all the patients rigid tracheoscopy and/or flexible bronchoscopy revealed the length of the stenosis and the distance from vocal cords. T-tube was placed under local anesthesia. The patients used to wear closed T-tube from 1-12 years. The tube was exchanged every 2-4 years. The only adverse effect was recurrent granulation around tracheostomy in two patients. 7 of 12 patients were decannulated with good result in 3 months - 5 years follow up. In two decannulated patients stenosis recurred. One patient was retracheostomized and in another patient stenosis was resected with end to end anastomosis. Three patients were not decannulated. Tracheostomy T-tube can be used temporary in patients with tracheal stenosis before planned stenosis resection or as a sole treatment with good chances for successful decannulation. When stenosis resection is not possible, T-tube can be placed for long time.
Otolaryngol Pol 2005
PMID:[The use of tracheostomy T-tube in the treatment of tracheal stenosis]. 1611 91

The case presents a 43 years old man, cigarette smoker, exposed to wood dust at work, with chronic, ineffective cough symptoms, limited physical exertion and recurring respiratory system infection. Disorders appeared at the age of 33 after severe double-sided pneumonia. Despite the lack of active clinical infection the following microorganisms: Pseudomonas aeruginosa and Staphylococcus aureus MSSA were isolated from patient bronchi mucus. Diagnosis followed image examination (CT, virtual bronchofibroscope). The following was recommended: quitting smoking, avoiding dust exposure at work, physiotherapy to ease mucus removal from bronchi and preventive vaccination. Tracheobronchomegaly consists in trachea clearance and central bronchi widening which disturbs air flow in air-passages and decreases cough effectiveness. Main symptoms are: paroxysmal cough, recurring bronchi inflammation and pneumonia resulting in mucus residing in air-passages.
Pol Merkur Lekarski 2005 Jul
PMID:[Mounier-Kuhn syndrome (tracheobronchomegaly)]. 1619 31

Subglottic laryngitis is one of the acute children's diseases, directly caused by a violently growing edema of the subglottic area. Its symptoms generally appear very suddenly, when children seem to be in perfect health, at night, several hours after falling asleep. Their symptoms included barking cough, clear voice, stridor, inspiratory dyspnoea with participation of auxiliary respiratory muscles, excitation and anxiety of a child, changes in skin coloration. The movement of the wings of the nostrils is intensified. In especially severe cases, agitation, cyanosis, pallor of skin, obnubilation, apnea, loss of consciousness and circulatory failure may also occur. Subglottic laryngitis is a disease, which can threaten the life of a small child. The aim of this study was to observe efficacy of the treatment of the subglottic laryngitis with glucocorticoids, especially budesonide in nebulization. The research covered 169 children: 58 girls (34.31%) and 111 boys (65.69%) aged 9. months do 5. years (mean 3 years 6 months) hospitalized in the Children's Hospital in Warsaw with the following symptoms: dry barking cough, stridor, inspiratory dyspnoea with the participation of auxiliary respiratory muscles, agitation and change of colour of skin. The examination of each patient included subjective, objective (pediatric and laryngological). Disease severity was assessed by a clinical croup score based on stridor, cough retractions, dyspnoea and cyanosis and the overall clinical assessment was scored on a visual scale. The results indicate that nebulised budesonide can be used as a safe and effective alternative treatment in children with moderate to severe subglottic laryngitis.
Otolaryngol Pol 2005
PMID:[Glucocorticosteroids in the treatment of subglottic laryngitis in children]. 1627 61

Organising pneumonia (OP) is a rare syndrome that has been associated with a variety of underlying disorders, including infections, collagen vascular diseases, toxic fumes, cancer, drugs and radiotherapy. Cryptogenic form is also observed. Steroids are usually effective in the treatment of OP, but other treatment regimens have been used as well. We present 5 women with OP, age ranged 57-76 years (mean - 67 years). Two of them were smokers and three were non-smokers. One patient was treated because of hyperthyreosis, one of COPD, and four had a hypertension. Four of them were diagnosed by the open lung biopsy and one by transbronchial lung biopsy. Dyspnoea (100%), cough (100%), fever (80%), weight loss (40%), chest pain (20%), were the most frequently noticed symptoms. All patients had bilateral consolidations with areas of ground glass attenuations at chest x-ray and HRCT. Migratory pattern of them was observed in four patients. Significant elevation of antibodies titers against Chlamydia pneumoniae was revealed in two patients. In all patients clarithromycin in a dose 0.5 g b.d. was administrated. Complete clinical and radiological remission was obtained after 3 months of clarithromycin therapy in 3 patients (one had Chlamydia antibodies). Two patients had not obtained significant improvement during the first two weeks of therapy so prednisolone in a dose 0.5 mg/kg/d was introduced. Also complete remission was noticed in these patients. The observation period ranged from 8 months to 4 years (mean - 34 months). Our study confirms that OP can be treated by the use of clarithromycin. It may be the alternative treatment, particularly for patients in whom probability of adverse reactions in the course of steroid treatment is high.
Pneumonol Alergol Pol 2004
PMID:[Organizing pneumonia--own experiences with clarithromycin treatment]. 1632 49

Unmyelinated C-fibers endings lye beneath the epithelial layer and release neuropeptides which regulate baseline transepithelial potential difference (PD) and changes of transepithelial potential difference during mechanical stimulation (dPD). Ambroxol can suppress reflexes such as the cough or the corneal reflex which are connected to stimulation of C fibre endings. The study aimed to estimate the influence of ambroxol (ABX) and capsaicin (CAPSA) on PD and dPD in isolated rabbit bladder. The experiments were carried out on 26 bladder specimens of. 2 cm2 surface area each, obtained from 13 rabbits. Ussing apparatus was used. Procedure used for stimulation of sensory receptor involved directing stream onto epithelium. A stimulus lasted 30s, ejecting the 2.5 ml fluid. Amiloride and bumetanide were used to estimate of ionic currents. Each significant reaction was repeated at least 10 times on various specimens. PD ranged between 5 and 10 mV in different experimental conditions. Mechanical stimulation of isolated bladder wall caused increasing dPD about 2 mV defined as hyperpolarization. Application of ABX to the stimulation fluid decreased the hyperpolarization in comparison with control stimulation under conditions of inhibited chloride ion transport. Application of CAPSA to the stimulation fluid decreased the hyperpolarization in comparison with control stimulation under conditions of inhibited sodium ion transport. ABX and CAPSA had no influence on PD after mechanical stimulation. ABX as well as CAPSA influence on transepithelial ion transport pathways in bladder epithelium is dependent on sensory stimulation. ABX can be suspected to suppress bladder contractions.
Acta Pol Pharm
PMID:The influence of ambroxol and capsaicin on the isolated rabbit bladder wall. 1645 89

Pertussis is highly contagious respiratory tract disease, which is caused by gram-negative bacteria Bordetella pertussis. It can be difficult to diagnose in adult patients, because of the fact, that whooping cough which is the most characteristic symptom of pertussis, is uncommon. Each adult patient with prolonged and nonspecific cough should be considered in a case of pertussis. Erythromycin is an antibiotic of choice in pertussis treatment.
Pol Merkur Lekarski 2005 Nov
PMID:[Pertussis in adult patients]. 1649 22

Influenza viruses represent Orthomyxoviridae family. Spherical virions are 80-120 nm in diameter and have two-layer lipid envelope. The following proteins are coded by 8 or 7 segments of the single-stranded RNA: nucleoprotein (NP), polymerase PB2, PB1 and PA, member protein--M1 and M2, glycoproteins--hemagglutinin (HA) and neuraminidase (NA). HA and NA form spikes on the virion surface. On the basis of antigenic differences there are distinguished three types of influenza virus-A, B and C. Besides, influenza A viruses occur in different subtypes, depending on the features of HA and NA. One of influenza characteristics is its antigenic changeability: antigenic drift and antigenic shift. Infection occurs by droplet route, sometimes through direct contact with infected person or surface. Influenza virus attacks epithelial cells of upper respiratory tract, where replication takes place resulting in the production of approximately 1000 of progeny virions during a single 6-12 h cycle in one cell. Necrosis of ciliary cells of mucosa facilitates invasion of bacterial pathogens. Incubation period lasts on average 1-2 days. Influenza illness without complications characterizes the sudden onset of respiratory symptoms and systemic symptoms. Regression of symptoms usually occurs after 3-5 days, but cough and malaise may be observed for over 2 weeks. Reasons for the severe course of the disease or even death are post-influenza complications, e.g. viral pneumonia and bronchitis, bronchiolitis in children, secondary bacterial pneumonia, otitis media, myocarditis and pericarditis, Reye's syndrome, myositis, myoglobinuria, neurological complications and exacerbation of existing chronic diseases. In the case of influenza there is no possible to make the unquestionable diagnosis only on the basis of clinical picture of the disease. Therefore in some circumstances there is important to make some diagnostic laboratory tests as RT-PCR, immunofluorescence assay or isolation of virus and detection of the specific antibodies. The main determinants of the immunity to influenza virus infection are antihemagglutinin (anti-HA) antibodies and antineuraminidase antibodies (anti-NA). The former play fundamental role for the protection against the infection, while anti-NA antibodies limit virus spreading and contribute to a milder course of the disease. In the response to influenza infection there are observed serum immunoglobulines IgG and IgM (after the first contact with the antigen), while immunoglobulines IgA are produced rarely. The latter are produced locally in the high concentrations on the mucus of respiratory tract. Cellular immunological response is important for recovery from influenza where a significant role of cytotoxic T lymphocytes should be emphasized. These lymphocytes are able to kill infected cells in the earliest phases of replication before the progeny virions are formed.
Pol Merkur Lekarski 2006 Sep
PMID:[Various sides of influenza, part I--structure, replication, changeability of influenza viruses, clinical course of the disease, immunological response and laboratory diagnostics]. 1716 90

Angiotensin converting enzyme inhibitors (ACE-I) are generally-applied medicaments in treatment and prevention of many illnesses. Although they are generally well-tolerated by an organism, their application might cause side-effects in a respiratory system, such as: dry cough, angioedema. They can also cause or strengthen bronchospasm. In this paper we analyse mechanism responsible for ACE-I side-effects concerning the respiratory system. The paper also highlights a positive effects of lung fibrosis and reduction of pneumonia risk in elderly people.
Pol Merkur Lekarski 2006 Sep
PMID:[Angiotensin converting enzyme inhibitors and respiratory system]. 1716 92


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