Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A girl with Thalassemia major reacted to a transfusion of packed red blood cells with increasing respiratory distress until death 12 1/2 hours later. Chills and fever were followed by dry cough, dyspnea, and pulmonary edema. The recipient had lymphocytotoxic antibodies specific for donor leukocyte antigens HL-A11 and possibly W14. At autopsy, the lungs showed pulmonary edema with extensive nonspecific acute alveolar injury. Similar cases in the literature are reviewed.
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PMID:Fatal pulmonary hypersensitivity reaction to HL-A incompatible blood transfusion:report of a case and review of the literature. 125 14

The drug abuse monitoring study of Regional Medical Research Center, Dibrugarh, reported 181 and 395 addicts from the states of Assam and Nagaland respectively in one year. Of these, 48 (26.5%) and 49(12.4%) cases were contributed by the primary abuse of codeine containing cough syrups. A11 addicts were males in their early twenties. Most of the addicts were unmarried and educated up to matriculation. The majority of addicts in Assam were Hindus (85.4%) and in Nagaland Christians (81.63%). Unemployment was predominant in both the groups. The mean age for the first use of codeine cough syrup was 17.44 years (Assam) and 15.77 years (Nagaland). Nagaland had more chronic abusers. Addicts were used the oral route several times a day and friends were the main source of introduction. Mild forms of physical and psychiatric disorders were reported Easy over-the-counter availability, lesser expenditure, milder withdrawals and ease of consumption without secrecy were some of the reasons for the emergence of this new form of addiction in Assam and Nagaland.
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PMID:Codeine containing cough syrup addiction in assam and nagaland. 2174 87