Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Knowledge of filariasis and perceptions of the disease were explored among 413 lymphoedema cases attending two filariasis clinics in the Colombo district of Sri Lanka. The information was collected in interviews based on a pre-tested, interviewer-administered questionnaire. Only 15% of the patients had initially attributed their limb swelling to filariasis. Most knew that filariasis resulted from mosquito bites (81.1%) and that the disease is transmissible (59.8%) and preventable (74.3%). The majority did not know, or were uncertain, whether filariasis causes swelling of the breasts in females (68.5%), scrotal swelling (60.7%) or dry cough/breathlessness (62.7%). Most (60%) of the interviewees wrongly believed that chronic filarial lymphoedema could be cured, primarily by long-term treatment with diethylcarbamazine. Knowledge of filariasis was significantly associated with level of education (P<0.05). Curiously, compared with the male interviewees, the females interviewed were much less likely to say that filariasis was the cause of their initial swelling (P<0.001). Those who had suffered with the disease for more than 1 year were not significantly more knowledgeable about the disease than the interviewees who had developed symptomatic filariasis more recently. Knowledge about the symptoms of filariasis was generally poor in the study population. In order to dispel several common myths about the disease, health-education programmes, that are targeted both at the community in general and at primary-care providers, are clearly needed.
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PMID:Knowledge and perceptions of filariasis in Colombo, Sri Lanka, among patients with chronic filarial lymphoedema. 1736 96

Bird related hypersensitivity pneumonitis (HP) is becoming more common than other forms of HP around the world. We present two cases of HP, associated with exposure to visiting birds which had nested within their homes in semi urban areas of Colombo, Sri Lanka. A 65-year-old female (case 1) and a 61-year-old male (case 2) presented to the chest clinic complaining of gradually progressive and persistent chronic dry cough and dyspnoea during the year 2018. Both were found to have close contact with red-vented bulbuls (Konda kurulla) in their homes for more than 6 months prior to onset of symptoms and denied any other risk exposures in detail history taking. In both patients, high-resolution computed tomography chest (HRCT) showed centrilobular nodules of ground glass density with significant lobular air trapping. Video-assisted thoracoscopic (VATs) lung biopsy of case 1 showed patchy and focal interstitial thickening with lymphocytic infiltrate, minimal fibrosis, and few noncaseating granulomata within the interstitium. Transbronchial lung biopsy of case 2 showed thickened alveolar septae with lympho-histiocytic infiltrate and occasional neutrophils and eosinopils. Both showed severe reduction in forced vital capacity (FVC) at presentation. Multidisciplinary diagnosis of HP associated with red-vented bulbuls was made. Both achieved good improvement in clinical, lung function, and radiological assessment following removal of offending antigen exposure and treatment with oral corticosteroids.
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PMID:Hypersensitivity Pneumonitis Associated with Red-Vented Bulbul: A New Encounter of Bird Related Hypersensitivity Pneumonitis. 3188 2