Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 19-year-old female with aplastic anemia who developed subglottal aspergillosis is reported. She presented with fever, cough and stridor. Inspiratory dyspnea progressed rapidly and emergent tracheostomy was performed, which confirmed the diagnosis. In spite of intensive anti-fungal treatment combined with adoptive immunotherapy, Aspergillus infection expanded and she died of pulmonary aspergillosis. Autopsy revealed the fungal mass obstructing the trachea and disseminated pulmonary aspergillosis. Difficulties in diagnosis and management of subglottal Aspergillus infection are discussed.
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PMID:Invasive subglottal aspergillosis in a patient with severe aplastic anemia: a case report. 1209 52

Laryngeal dyspnea is a life-threatening emergency situation. The diagnosis is clinical and made from the association of: inspiratory bradypnea, intercostal and sus-sternal inspiratory depression, with or without stridor. The aetiologies are most often laryngeal tumours or inflammatory oedema; incidence of epiglottitis has decreased due to vaccine against Haemophilus influenzae. Airway obstruction due to foreign body includes acute laryngeal dyspnea and reflex paroxysmal coughing without fever. Management of a laryngeal dyspnea depends on the aetiology and the severity of clinical symptoms. Medical treatment associates racemic epinephrine aerosol, steroids, and oxygenation. In the presence of severe dyspnea, intubation after anaesthetising the patient and positive pressure ventilation is required.
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PMID:[Acute laryngeal dyspnea]. 1281 38