Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 56-year-old woman was initially seen in March 1998 with a complaint of back pain. Her thyroid gland was swollen and the level of TSH was elevated at 10 microU/ml. Chronic thyroiditis with hypothyroidism was diagnosed. Negative reactions were obtained for both anti-thyroglobulin and anti-thyroid peroxidase antibodies. Daily treatment with thyroxine 50 mg was started. A cough developed in August 1998, and her chest radiographs revealed multiple bilateral consolidation shadows. A transbronchial lung biopsy specimen demonstrated mononuclear cells infiltration in the alveolar septa with fibrosis, consistent with nonspecific interstitial pneumonia (NSIP). There were no findings clinically or serologically suggestive of collagen-vascular diseases. Ultimately interstitial pneumonia compatible with the NSIP pattern in association with chronic thyroiditis was diagnosed. Oral prednisolone (30 mg/day) and azathioprine (50 mg/day) administration was initiated. The cough and the shadows on the chest radiographs improved. However, one year after completion of the treatment, interstitial pneumonia recurred. Retreatment with prednisolone and azathioprine has resulted in its improvement.
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PMID:[Interstitial pneumonia associated with chronic thyroiditis]. 1192 15

Due to the large group of patients with advanced testicular cancer now being cured, it is important to identify the men who are at risk of deteriorated health. The purposes of this study were: (1) to delineate and compare frequency of self-perceived physical, psychologic, and general symptoms in men treated for testicular cancer with those of a general population sample and (2) to compare self-perceived physical, psychologic, and general symptoms in relation to secondary Raynaud phenomena, sexual dysfunction, infertility, and self-perceived attractiveness in different treatment modalities. The subjects were 277 survivors of testicular cancer (M = 42.2 years) who had completed a self-reported questionnaire (75.5% response rate). A population survey comprising 392 men was used as a comparison group (M = 45 years). The result demonstrated that although survivors of testicular cancer as a group reported significantly less frequency of backache, leg pain, cough, and eye problems than did the general population sample, they described that they significantly more often felt cold. Men reporting secondary Raynaud phenomena, infertility, and/or feeling less attractive had experienced significantly more self-perceived symptoms. Oncologist nurses could play an important role in psychologic counseling for those men.
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PMID:Self-perceived physical, psychologic, and general symptoms in survivors of testicular cancer 3 to 13 years after treatment. 1204 Feb 27

We report two patients who were long-time habitual consumers of alcohol and suffered from thoracopancreatic fistula. The first patient, a 52-year-old man with no symptoms, underwent chest CT scan for a medical check-up and was revealed to have left small pleural effusion. A month later, he suddenly experienced severe cough and back pain. The immediate CT scan showed massive pleural effusion and mediastinal pseudocyst, and the amylase level in the aspirated pleural effusion proved to be elevated. He was successfully treated with medication and drainage of the effusion. The second patient, a 39-year-old woman, underwent CT scan for a medical check-up, and it disclosed that she had a small pleural effusion in the left lower thorax. Follow-up CT two months later revealed the pleural effusion to be resolved, however, it demonstrated that a narrow tract derived from the pancreatic secretion located just posterior to the pancreatic tail extended to the mediastinum along the left hemidiaphragmatic crus. She experienced severe cough and sputum four months later. CT scan showed massive pleural effusion in the left thorax and revealed that the pancreaticopleural fistula was located in the same position as the small tract that had been detected by the previous CT scan. The patient received conservative treatment and eventually recovered from the severe chest complications. We consider that asymptomatic left small pleural effusion in these patients who were habitual drinkers is a potential precursor to symptomatic pancreatitis. The patients developed mediastinal pseudocyst and pancreaticopleural fistula in association with chronic pancreatitis within a few months, and therefore intensive follow-up should be undertaken to minimize or prevent chest complications in association with the subsequent symptomatic pancreatitis.
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PMID:Two cases of thoracopancreatic fistula in alcoholic pancreatitis: clinical and CT findings. 1229 38

A 73-year-old Korean male was admitted to Jeil hospital with clinical complaints of backache, cough, sputum, vomiting and diarrhea. He had a history of long term administration of prednisolone. At admission he was comatose and showed generalized pitting edema and anasarca. Laboratory data revealed leukocytosis, hyperproteinemia with hypoalbuminemia, sepsis, anemia and brown-colored urine. Stool examination revealed rhabditiform nematode larvae. By fecal cultivation, filariform larvae of Strogyloides were obtained and the patient was diagnosed as hyperinfection syndrome due to S. stercoralis infection. On the 3rd day of hospitalization, albendazole treatment was started and continued for 4 days. On the 7th dsy of hospitalization, sputum revealed filariform larvae. Total 619 parasitic adult females, expelled by chemotherapy, were collected from the diarrheal stool. However, the patient was discharged hopelessly and died at home.
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PMID:[A case of strongloidiasis with hyperinfection syndrome] 1281 Oct 51

Peritoneal dialysis (PD) is associated with a number of complications, some of which can be attributed to raised intra-abdominal pressure. Intra-abdominal pressure is highest during coughing or straining--activities which, fortunately, are transient. High pressure, primarily due to high volumes of PD solution, can predispose patients to hernias, dialysate leaks, and back pain; it can also cause altered mechanics of breathing. This article reviews those various complications and their management.
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PMID:Complications of peritoneal dialysis related to increased intra-abdominal pressure. 1476 49

A 37-year-old man was admitted to our hospital. The patient noted sudden right back pain after coughing before 1 hour. Loss of consciousness was occurred in an ambulance. Chest X-P revealed whole fluid in the right chest. Enhanced chest computed tomography (CT) revealed extravasation of contrast media into the pleural cavity from the right chest wall. Thoracentesis was performed to relieve dyspnea and 2,000 ml of blood was removed. Then hemoglobin count was dropped to 3.8 g/dl. At thoracotomy whole blood was sucked about 3,900 ml. Bleeding point was found at third intercostal vein. The vein was knotted and sutured by prolene thread. The bleeding lesion was no inflammation and no string like tissue. We report a case of idiopathic hemothorax and enhanced chest CT was useful for diagnosis of bleeding lesion of pleural cavity.
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PMID:[Idiopathic hemothorax associated with shock during transporting in an ambulance; report of a case]. 1528 90

Ewing sarcoma is a bone tumour that commonly appears between ages five and 10 in the diaphysis of the long bones and predominantly presents with pain and swelling. The case of an 18-year-old girl who presented with back pain, cough, dyspnea, weakness and fever is described. Chest radiograph showed a homogenous density in the middle and inferior zones of the right hemithorax. Thoracic computed tomography revealed a diffuse pleural effusion and a 6.99 cm x 4.45 cm solid mass composed of lobulated, small cystic lesions and calcifications in the right hemithorax. Biochemical analysis of pleural fluid showed hemorrhagic effusion and exudate. A pleural needle biopsy demonstrated solid uniform tumour cells with narrowed cytoplasm, round nuclei and uncertain nucleoli. All of the tumour cell cytoplasms stained with CD99. The pathological examination supported Ewing sarcoma. Three-phase Tc-99m methylene diphosphonate scintigraphy of the whole body showed pathological tracer uptake in a broad area of the eighth costal bone and in smaller areas of the ninth and 10th costal bones. This case is reported because Ewing sarcoma is a rare cause of pleural effusion in clinical practice among younger adults.
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PMID:Massive pleural effusion in an 18-year-old girl with Ewing sarcoma. 1533 40

Candesartan cilexetil is the prodrug of candesartan, an angiotensin II receptor antagonist. Candesartan binds selectively and non-competitively to the angiotensin II receptor type 1, thus preventing the actions of angiotensin II. Clinical trials have demonstrated its efficacy at a dose range of 2 to 32 mg once daily in hypertension of all grades, heart failure, in reducing urinary albumin excretion in diabetes mellitus and in coexisting hypertension and renal failure. Pharmacokinetic properties of candesartan cilexetil in elderly patients are not significantly different from those in younger individuals. Hepatic impairment does not change pharmacokinetics of candesartan cilexetil at doses up to 12 mg/day. No dose adjustment is necessary in patients with mild or moderate renal impairment. Tolerability of candesartan cilexetil is not much different from that of placebo. All adverse events are usually of mild to moderate severity and not dose-related. The most common adverse events were headache, upper respiratory tract infection, back pain, and dizziness. The incidence of these adverse effects, as well as of cough, was similar in patients treated with candesartan cilexetil or placebo. The incidence of adverse events in long-term trials was not different from that in short-term trials. Tolerability of candesartan cilexetil does not differ with either age or gender.
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PMID:Candesartan. 1559 74

Recognizing similarities and differences in symptom experiences of acute myocardial infarction (AMI) between men and women has implications for both health care providers and the general public. Rapid accurate diagnosis is necessary to implement timely lifesaving treatment. The purpose of this article is to critically review and evaluate studies that have compared symptoms of AMI between men and women. Research to date has demonstrated that during AMI, women are more likely than men to report shortness of breath, nausea, vomiting, back pain, jaw pain, neck pain, cough, and fatigue, but less likely than men to report chest pain and sweating. However, the findings were inconsistent across studies. These inconsistent findings could be attributable to methodological issues such as collecting data from medical records, small sample sizes, and controversial eligibility criteria for studies. More studies are needed to confirm gender differences in symptom experiences of AMI.
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PMID:Gender differences in symptoms associated with acute myocardial infarction: a review of the research. 1602 43

The study reports a questionnaire based survey on mill operators in a large market in Ibadan, Southwest Nigeria. One hundred and twenty respondents, 65 males and 55 females aged between 18 and 65 years were interviewed and noise measurements were done at various work stations. Health problems reported by these workers include headaches 73%, backache 53% and respiratory symptoms such as cough 37% rhinitis 63% and wheezing 13%. Thirty four respondents (28%) reported a difficulty in hearing mostly due to tinnitus. Four complained of deafness. Twenty-three (19%) had raised blood pressure of 140/90Hg and above. In spite of the high levels of dust in the work environment only 15 (13%) of workers used a face cloth to cover their noses. Noise levels at the work stations ranged from 88-90dB from smaller machines and 101-105 dB for larger machines. None of the workers used hearing protection in any form. Health education of workers and the provision of low cost protective equipment may alleviate the suffering of these workers.
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PMID:Health problems of mill operators in a tropical African population. 1627 7


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