Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Varicella pneumonia during pregnancy may be relatively mild or rapidly fatal. Diagnosis is based on the usual criteria for varicella in association with signs and symptoms of respiratory distress: dyspnea, tachypnea, cough, chest pain, and hemoptysis, with characteristic x-ray findings. Treatment should be directed toward maintaining blood oxygen saturation at as near normal as possible (monitored by serial blood gas determinations). The occurrence of congenital varicella is unpredictable, but an infant born within four days of the mother's development of the varicella skin rash is at high risk, with the outcome being fatal in five percent of cases.
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PMID:Varicella pneumonia during pregnancy. 42 71

Varicella pneumonia is the most common complication of chickenpox and it also has the highest mortality. A retrospective study was carried out on 10 patients with varicella pneumonia over a period of one year. Seven of the 10 patients with varicella pneumonia had a history of smoking. The majority of the patients with varicella pneumonia presented with cough, dyspnoea, hypoxia and a compatible chest radiograph. All the patients with varicella pneumonia were treated with intravenous acyclovir. Four patients required mechanical ventilation. Nine out of the 10 patients were cured with only one death. It may be reasonable to select adults with varicella and who smoke, for early treatment with acyclovir.
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PMID:Varicella pneumonia in adults--clinical spectrum. 905 8

Varicella pneumonia is one of the serious complications of primary varicella zoster virus (VZV) infection in adults. A 36-year-old woman with end-stage renal disease underwent renal transplantation from a living donor in 1998, receiving immunosuppressive treatment with cyclosporine, mycophenolate mofetil, and methylprednisolone. She had a history of VZV infection during childhood. The patient developed an intractable cough on December 10, 2006, but there were no abnormalities in the laboratory data or chest radiograph for several weeks. On January 1, 2007, she was admitted to our hospital with cutaneous vesicles covering the entire body. We learnt that when her symptoms developed, her son was diagnosed with varicella. The chest radiograph at this stage showed a diffuse miliary pattern in the entire lung field. We started intravenous administration of acyclovir. VZV antigen was detected in the cutaneous lesions and VZV antibody in the serum after the start of these treatments, so we continued to administer acyclovir for 18 days. The cutaneous lesions healed and the pneumonia improved based on the chest radiograph. She was discharged from the hospital on January 19, 2007. In conclusion, this report documents VZV reinfection in a transplant patient.
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PMID:Pneumonia due to varicella-zoster virus reinfection in a renal transplant recipient. 1991 24