Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of primary mediastinal haemangiopericytoma in a 29-year-old female patient who presented with haemoptysis, cough and dyspnea. Computed tomography showed a 9 x 6 x 5 cm mass in the left posterior mediastinum. Bronchoscopic examination failed to obtain biopsy because of massive bleeding. The patient underwent left thoracotomy. Mediastinal mass and left lower lobe resection was performed despite the persistent bleeding. The lower lobe bronchus had been infiltrated by the tumour. Microscopic examination revealed a highly cellular tumour composed of round to fusiform cells, surrounded by thin walled endothelium lined vascular channels with a staghorn appearance. Immunohistochemical and molecular techniques rule out other soft tissue tumours which have a haemangiopericytoma-like vascular pattern. The patient is alive and free from tumour recurrence 6 months post-operatively.
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PMID:Primary mediastinal haemangiopericytoma--an unusual cause of massive haemoptysis in a young woman. 2051 43

Tuberculosis (TB) is a systemic disease that can affect all parts in the body. The clinical manifestations sometimes mislead to other diagnoses. Mediastinal mass-like of TB in children is a rare manifestation. A 5-month-old boy presented to our hospital with respiratory distress, fever for 2 months, body weight loss, cough, and history of recurrent pneumonia. The lung sound decreased on the right hemithorax. Lung computed tomography revealed multiple irregular cysts with thick walls on the anterosuperior mediastinal area, consolidation on the right lobe, and suspected gangrenous lung disease. The right main bronchus stenosis with cheesy-like vegetation was found on flexible bronchoscopy procedure. Xpert/MTB RIF from bronchoalveolar lavage revealed Mycobacterium tuberculosis and sensitive to rifampicin. Anti-TB drugs were given for 12 months. He has clinical and radiological improvement. We must increase the awareness of TB disease in case of mediastinal mass-like appearance in the high-endemic area. The flexible bronchoscopy plays an important role in diagnostic purpose.
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PMID:The role of flexible bronchoscopy in lung tuberculosis mimicking mediastinal mass in an Infant: A rare case report. 3121 Jan 67