Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An epidemic of infection due to Mycoplasma pneumoniae occurred in Hong Kong in 1986-1988. One hundred and seventy-nine cases were identified at the Prince of Wales Hospital over this period. Clinically significant infection predominantly affected children under 12 years, with 32% of all infections occurring in children aged between 6 and 11 years, and 39% in children between 1 and 5 years. Ninety-seven percent of childhood infections were respiratory in nature, the other 4 presentations were neuropsychiatric. Adequate information was available on 36 of the 43 subjects over 12 years. One teenager presented with acute psychosis; all other cases (35) were respiratory. In these cases cough was universal, and fever was present in 34 (97%). A variety of non-specific symptoms (rigors/chills, malaise, headache, sore throat, sweating) were frequently noted. Sputum production was documented in 75% of cases, and was frequently purulent. Radiological consolidation was very common (95% of cases), but resolved fully after 4 weeks. Complications were rare and included acute pericarditis in 1 patient and haemolysis in another, and both patients recovered subsequently. Clinical recovery was otherwise rapid and complete in all other patients. Persisting dry cough was the only symptom documented at follow-up. Although infection due to M. pneumoniae in an ethnic Chinese population appears similar to that described in other populations, a higher incidence in younger children was recorded in this study.
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PMID:Mycoplasma pneumoniae infection in Hong Kong--clinical and epidemiological features during an epidemic. 826 80

Tuberculosis accounts for up to 4% of acute pericarditis and 7% cases of cardiac tamponade. Prompt treatment can be life saving but requires accurate diagnosis. We report a case of 30-year-old male who presented with fever, chills, and dry nonproductive cough since one month. The case was diagnosed by radiological findings, which were suggestive of pulmonary tuberculosis, followed by acid fast staining and culture of the aspirated pericardial fluid. The patient was responding to antitubercular treatment at the last follow up.
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PMID:A case of tuberculous pericardial effusion. 1917 70

Pneumomediastinum (PM) is a rare cause (the rate varies from 1:8500 to 1:30000 patients) of pain in the chest. This is generally a benign entity resulting from alveolar rupture and propagation of the air into the mediastinum that affects mainly young adults. It may appear however as a complication of different procedures within the chest. Asthma, cough, vomiting, illicit drug use and all activities that require the Valsalva maneuver and/or intense breathing work or exercise were identified as predisposing factors of PM. We report cases of two patients admitted within some months to the emergency department due to chest pain. Due to acute onset of symptoms and a presence of a loud murmur along the left border of the sternum the acute pericarditis was suspected. However, after careful and detailed examination acute coronary syndrome and pericarditis were excluded. Radiologic examination and computed tomography of the chest revailed the presence of air in the mediastinum in both cases. After the diagnosis of pneumomediastinum antiinflammatory agents and antibiotics were administered. Recovery was uneventful, within two weeks form the onset a complete resolution of radiologic changes were observed.
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PMID:[Pneumomediastinum as a rare cause of retrosternal chest pain--report of two cases]. 2223 7

We report the case of a 19-year-old male patient admitted to hospital with fever, asthenia, vomiting, abdominal and chest pains, cough with yellowish sputum, and hypotension. Laboratory tests showed leukocytosis and high creatine phosphokinase levels, without hyperbilirubinaemia or renal failure. The tomographic images of the chest and abdomen showed a right basal pneumonia and acalculous cholecystitis. The electrocardiograms revealed significant characteristics of acute pericarditis. Specific serology for leptospirosis done in the second and third weeks of disease showed positive results. The use of ceftriaxone 1g intravenously, twice a day for 7 days, resulted in an overall clinic improvement. The role of the suspicion index for diagnosis of leptospirosis is emphasized in anicteric patients, as well as the unsuspected possibility of pulmonary, pericardial and gallbladder involvement.
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PMID:Anicteric leptospirosis with pneumonitis, pericarditis and acalculous cholecystitis. 2526 67

We describe a seven-year-old female with acute pericarditis presenting with pericardial tamponade, who screened positive for coronavirus disease 2019 (COVID-19 [SARS-CoV-2]) in the setting of cough, chest pain, and orthopnea. She required emergent pericardiocentesis. Due to continued chest pain and orthopnea, rising inflammatory markers, and worsening pericardial inflammation, she underwent surgical pericardial decortication and pericardiectomy. Her symptoms and pericardial effusion resolved, and she was discharged to home 3 days later on ibuprofen and colchicine with instruction to quarantine at home for 14 days from the date of her positive testing for COVID-19.
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PMID:Pediatric COVID-19 and Pericarditis Presenting With Acute Pericardial Tamponade. 3290 90