Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A role of nutrients in the onset of migraine and other gastrointestinal symptoms (vomiting, nausea, diarrhoea), skin reactions (rush, atopic dermatitis, Quincke'a edema), respiratory symptoms (bronchial asthma, cough, allergic rhinitis, polyps, congestion of the nasal mucosa), motion system disorders (jointache and edema), gynecological disorders (chronic and recurrent adnexitis), and sleep disorders together with emotional tension and behavioral disturbances has been assessed in 17 patients with atopy. Migraine attacks have been produced most frequently by cow milk (in 10 out of 17 patients), cabbage, flour and eggs in 5 patients, preservatives, cottage and Swiss cheese, porcine meat in 4 patients, colorants and chocolate in 3 patients, beef, strawberries, lemons and butter in 2 patients. Other nutrients produced headache in single patients. Migraine and other symptoms have diminished after an individual elimination diet. Recurrence has been noted after each consumption of allergen except one female patient with EEG abnormalities. Immunoglobulins E have been involved in headache-producing mechanism in 3 patients.
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PMID:[Migraine as one of the symptoms of food allergy]. 135 12

The Chiari type I malformation has recently been reported in three generations of a family, including female monozygotic twins. Headache was the main symptom in several family members. Various headache patterns consistent with migraine without aura, cough headache, tension headache and hypoliquorrhoeic headache were present, and different patterns might coexist in the same patient. In the twins and their mother, who all had a headache consistent with migraine without aura, there were atypical features such as occipital pain location, lack of side-shift of the pain, lack of ergotamine effect and precipitation of attacks by Valsalva-like manoeuvres. The headache was significantly relieved by operation in the one twin with major herniation and the most marked headache. We suggest that in these patients the migraine-like headache mimics true migraine but that there is a causal relationship between the different headache types reported and the malformation.
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PMID:Headache and Chiari type I malformation: occurrence in female monozygotic twins and first-degree relatives. 142 62

Pharmacotherapy is the mainstay for patients with persistent headaches. When simple analgesics can no longer be used, combination analgesics are prescribed. Symptomatic medications also include antiemetics, ergot derivatives, corticosteroids, neuroleptics, and narcotics. Nonsteroidal anti-inflammatory drugs are commonly used both symptomatically and prophylactically, and are the treatment of choice for menstrual migraine. Exertional migraine, benign orgasmic cephalalgia, chronic paroxysmal hemicrania, cough headache, and "ice-pick" headache are treated with indomethacin. Ergotamine tartrate is often recommended when simple or combination analgesics do not relieve headaches. Dihydroergotamine (DHE) is effective for treating intractable headache; because it has fewer side effects than ergotamine, it is tolerated by patients unable to tolerate other ergotamine preparations. DHE is administered IM and, for occasional use, patients can be taught self-injection. Repetitive IV DHE therapy for chronic severe headaches requires hospitalization; most patients become headache-free within 3 days. Patients who refuse hospitalization, do not respond to the drug, or are not suitable candidates for DHE therapy may receive a short course of a corticosteroid, a neuroleptic or, rarely, a narcotic. For frequent headaches, prophylactic treatment usually begins with a tricyclic antidepressant or a beta blocker.
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PMID:Symptomatic and prophylactic treatment of migraine and tension-type headache. 155 87

We analyzed the headaches in 50 patients with type I Chiari malformation. Of the 50, 14 (28%) had a rather specific, usually protracted, suboccipital-occipital headache of variable quality and duration that was aggravated by Valsalva's maneuver, effort, cough, or postural changes and relieved by occipital-suboccipital craniectomy. Only the degree of tonsillar herniation significantly correlated with the presence of this pain. Both migraine and tension-type headache occurred with the expected frequency for the general population.
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PMID:Headache in type I Chiari malformation. 817 May 87

One hundred epileptic patients were questioned about their headaches. Post-ictal headaches occurred in 51 of these patients and most commonly lasted 6-72 hours. Major seizures were more often associated with post-epileptic headaches than minor attacks. Nine patients in this series of 100 also had migraine: in eight of these nine a typical, albeit a mild, migraine attack was provoked by fits. The post-ictal headache in the 40 epileptics who did not have migraine was accompanied by vomiting in 11 cases, photophobia in 14 cases and vomiting with photophobia in 4 cases. Furthermore, post-epileptic headache was accentuated by coughing, bending and sudden head movements and relieved by sleep. It is, therefore, clear that seizures provoke a syndrome similar to the headache phase of migraine in 50% of epileptics. It is proposed that post-epileptic headache arises intracranially and is related to the vasodilatation known to follow seizures. The relationship of post-epileptic headache to migraine is discussed in the light of current ideas on migraine pathogenesis, in particular the vasodilation which accompanies Leao's spreading cortical depression.
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PMID:Post-epileptic headache and migraine. 311 78

Acute superior laryngeal palsy is often clinically unrecognized and frequently overlooked. Yet, this motor paralysis occurs more frequently than facial paralysis. Like acute facial paralysis, superior laryngeal palsy often occurs as part of a cranial polyneuritis that is probably related to herpes simplex virus reactivation. Rotation of the larynx and shortening of one vocal cord have been found in such diverse syndromes as vestibular neuronitis, migraine and tension headaches, unexplained cough, tinnitus aurium, globus hystericus, and carotidynia. Electromyographic studies suggest that laryngeal spasm may be caused by faulty regeneration of the superior, rather than the recurrent, laryngeal nerve.
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PMID:Acute superior laryngeal nerve palsy: analysis of 78 cases. 682 26

Allergic reactions to food colors have been known since 1958. Reactions to tartrazine, our example, include generalized pruritus, urticaria, angioedema, paresthesias, vomiting, migraine, rhinorrhea and nasal obstruction, coughing, asthma attacks and purpura. Many patients who are allergic to antiinflammatory drugs such as acetyl-salicylic acid and indomethacin show cross-reaction to tartrazine. Doses producing these reactions range from minimal amounts up to 750 mg. Symptoms appear after periods of time ranging from minutes to 6 to 14 hours. In view of these facts (some of which represent a threat to the patient's life), additives, colouring matter, etc, do not usually appear in product labels or specifications, or in handbooks or catalogues used in practice. We drew up a list of drugs which may contain food dyes and coloring matter, yellow No. 5. A letter was written to 233 laboratories of which 159 (68%) replied. 72 (45%) in the affirmative and 87 (55%) in the negative, 74 (32%) did not reply.
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PMID:[Pharmaceutical preparations which contain tartrazine]. 725 46

Fifty patients were examined during a migraine attack to seek the site of origin of the headache. There being no single specific test for an intra-or extracranial source of head pain, we employed a series of manoeuvres: coughing, rapid side-to-side head rotation, and breath-holding for 30 seconds--indicative of an intracranial component. Digital compression of the superficial temporal artery, and a blood pressure cuff round the head to occlude the scalp circulation, were used as evidence of an extracranial component. Patients were asked to comment on the effect each of these procedures had on their headache. The observations suggest that in 49/50 an intracranial factor was operative, and in 21 of these no extracranial component was apparent. In 28/49 there seemed to be both intra- and extracranial contributions to the headache. One patient did not respond to any test. The evidence presented seems to implicate intracranial structures in the pathogenesis of migraine headaches.
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PMID:The site of pain origin during migraine attacks. 734 82

Seventeen patients with migraine headaches, occurring at least twice a month, were successfully treated with an ACE inhibitor for prophylaxis. Most were given enalapril, some used lisinopril. Duration of treatment ranged from 3 months to 3 years. Side effects were generally not noted. Cough occurred in four patients. The mechanism of action is unknown. The lack of side effects and the presence of clearly sustained benefit in this small group of migraineurs should prompt further study and use of this class of drugs for prophylaxis.
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PMID:ACE inhibitors for prophylaxis of migraine headaches. 759 40

Blue Cross of Atlantic Canada has revised its drug-benefit program by restricting the number of drugs eligible for automatic benefits. The program still covers more than 3000 medications, but not items such as nicotine-replacement products, antihistamines, or cough and cold medications. The centrepiece of the revised program is a "special-authorization" process that affects about 140 expensive but "commonly prescribed" drugs such as antidepressant products and medications for migraine treatment. Although may applaud the not-for-profit corporation's intentions, some doctors and patients have experienced difficulty adjusting to the changes.
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PMID:Some suffer adjustment pains as Blue Cross changes drug-benefit program on East Coast. 761 50


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