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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

5,576 people who had two or more of the following symptoms, running nose, cough, fever and crepitations/rhonchi over the chest were interviewed. 1,355 specimens of nasal and throat swabs from those interviewed were processed for viruses associated with upper respiratory tract infection. There was a sharp rise in 'flu-like symptoms in March 1976, followed by a much higher incidence from June, reaching a peak in August. Influenza A was isolated from most of the specimens collected. A few para-influenza II were also isolated. Our findings show that severe outbreaks of acute viral infection of the respiratory tract occurred during our wet season particularly around August.
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PMID:A 12-month surveillance of 'flu-like infections in a sample from the population of Lagos. 629 82

Infant rats infected with influenza A virus, Sendai (parainfluenza 1) virus or rat coronavirus were used to determine whether viral infection increases the intensity of nasal colonization with Haemophilus influenzae type b (HIB). Intranasal inoculation of HIB in rats previously infected with each of these viruses resulted in nasal HIB titers at least 100-fold higher than those for controls during the first 2 wk after HIB inoculation, and as much as 10,000-fold higher during the first week. Children with cough, sneezing, or rhinorrhea could be effective disseminators of HIB if they were as heavily and persistently colonized as these virus-infected animals.
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PMID:Viral enhancement of nasal colonization with Haemophilus influenzae type b in the infant rat. 630 51

Maedi-visna, a chronic viral disease of adult sheep characterized by progressive dyspnoea or neurological manifestations, was first recognized and described clinically in Canada in 1970. Seroepidemiological study was conducted in sheep and goats in various areas of Quebec. Sera of 10% of the animals of selected flocks were collected and specific antibodies against maedi-visna virus were tested by a modified direct complement fixation test. Results show seropositive rate of 67.6% for Sherbrooke sheep; of 40.5, 41.1 and 47.1% for Quebec, Saint-Hyacinthe and Nicolet sheep respectively and only 29.2 and 20.0% positive sera in l'Assomption and Rimouski animals. Prevalence rate of positive goats varied according to geographic areas (0 to 36.8%). Statistical analysis of various factors, e.g. age, breed, mode of raising, origin and size of flock showed no relation between these factors and the geographic areas. But, some clinical problems in the sheep flocks such as cough, rapid breathing, mortality and abortion were associated with high infection rate (greater than or equal to 50%) to maedi-visna virus. In goats, no correlation was demonstrated between these clinical signs and serological results. Our results suggest that it is important to consider this disease in an adequate program of preventive medicine in Quebec.
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PMID:Seroepidemiological survey of maedi-visna virus infection in sheep and goat flocks in Quebec. 631 98

Seven years after admission to hospital for acute lower respiratory tract infection in infancy 200 children and their matched controls were assessed for respiratory state and epidemiological characteristics. The index group comprised 100 cases where respiratory syncytial virus infection had been responsible for the index illness (group 1) and 100 cases in whom this organism had not been found (group 2). There were no differences between index and control groups in birth weight or gestational age but fewer index cases were breast fed. Social indices such as class distribution and family size were more favourable in controls, though housing standards and maternal smoking habits were similar in the two groups. The prevalence of subsequent respiratory symptoms--cough, wheeze, nasal discharge, and hearing difficulties--was greater in index cases as was absence from school and family doctor consultation for respiratory illness. Bronchitis and asthma were significantly more common in the index group. Impaired ventilatory function and bronchial hyperreactivity were found in index cases when compared with controls. No differences in clinical characteristics and outcome were found in the two groups of index cases. The question whether lung "damage" during lower respiratory tract infection predisposes to subsequent respiratory problems or whether certain infants are more vulnerable than others to respiratory illnesses (including lower respiratory tract infection) from the onset is unanswered.
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PMID:Outcome of acute lower respiratory tract infection in infants: preliminary report of seven-year follow-up study. 680 71

A patient suffering from acute lymphoblastic leukemia, in complete remission for two years, is treated for haematologic relapse with V.P.D. and C.O.A.P. consolidation. After this treatment, develops tiredness, sleepiness, a slight fever and cough, dying some days after, of interstitial pneumonia. Post-mortem anatomic-pathological studies, show giant cell multinucleated pneumopathia, with intranuclear inclusions bodies, that in ultrastructural level resembles paramyxovirus. When this complication took place, the patient had a brother with measles, but he hasn't, the typical symptomatology of said virus disease. According to Siegel, authors point out the frequency of death due to interstitial pneumonia as a complication caused by measles in immunodeficient patients, remarking the importance of an immediate diagnosis and its' prophylaxis.
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PMID:[Giant cell pneumonia. Complication in one case of acute lymphoblastic leukemia (author's transl)]. 693 58

The purpose of this study was to identify common acute symptoms that were significantly related to the decision to seek medical care. Data were from the Seattle Virus Watch, a 4-year study of 149 young families designed to monitor viral infection, regardless of medical care contact. Illness diaries were maintained by the families and checked for accuracy every 2 weeks during home visits by study personnel. Age sex, family unit, medical contact, duration and presence or absence of 80 symptoms in 17 categories were recorded for each illness. In 11,583 person-months of observation, 3,929 illness records were compiled. Using physician contact as the dependent variable and the illness information as independent variables, a series of discriminant analyses were performed on a 50% random sample of illnesses. Success of each analysis was tested on the remainder of the illnesses. Fever and ear symptoms were significant predictors in all age groups and cough was significant in four of five age groups. These symptoms are suggested as logical choices for health education programs in self-care of acute illnesses.
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PMID:Targeting symptoms for self-care health education: a multivariate analysis of physician contacts. 740 8

Bronchial responsiveness is closely associated with asthma in schoolchildren. We wished to test the hypothesis that bronchial responsiveness in the neonatal period might be a risk factor for lower-respiratory illnesses (LRI), typically cough and wheezing with viral infection, in infants. A cohort of 73 full-term healthy infants of atopic parents were observed during the first year of life. Respiratory illness was recorded and ascertained retrospectively by questionnaires administered to parents at 6-mo intervals, and infants were classified as having: LRI (one or more episode of wheezing in the first year) or no LRI (no wheezing). At approximately 1 mo of age, lung function was measured under sedation, and bronchial responsiveness (BR) to histamine aerosol was determined and expressed as PC30, the provocative concentration of histamine that induced a 30% decrease in maximum flow at FRC (V'maxFRC) by the squeeze technique. For the whole group, no index of lung function predicted subsequent wheezing. Among boys, however, there was a trend toward a lower V'maxFRC in those who subsequently developed LRI than in the group without LRI (median values 62 versus 98 ml/s; 95% CI: -1 to 68; p = 0.06), while among girls the major difference was in PC30, for which those who subsequently had LRI were significantly more responsive as neonates (PC30 was lower) than the group without LRI (1.4 versus 8.3 g/L; 95% CI: 1.0 to 13.1; p < 0.05). These findings suggest that sex differences in airway structure and responsiveness present soon after birth, and representing differences in fetal lung development, are associated with differences in the risk of subsequent LRI with wheezing.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Bronchial responsiveness in the neonatal period as a risk factor for wheezing in infancy. 773 97

There was an outbreak of "a mysterious disease" at a Zambian school dormitory in September, 1993. Investigation with questionnaire and collection of throat swab specimens for virus isolation were carried out on 46 patients to identify the causative agent. In this outbreak, most of the patients showed similar symptoms such as fever, headache, sore throat, cough, etc. The disease had spread to all dormitories within a couple of days after the onset of the first cases. From these patients, 13 influenza viruses A/H3N2 were isolated on MDCK cell line. This was a first ever confirmed outbreak of influenza virus infection in Zambia.
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PMID:An outbreak of influenza A/H3N2 in a Zambian school dormitory. 779 73

A 48-year-old woman was admitted to our hospital because of cough and low-grade fever. Chest X-ray films showed multiple ill-defined nodular shadows and laboratory findings showed that she was an ATL-virus carrier. Because the specimens obtained by transbronchial biopsy were not diagnostic, open thoracotomy was performed. Open lung specimens showed proliferation of lymphoid cells composed of polymorphorous lymphocytes, which do not represent cytologic atypia, plasma cells and histiocytes without necrosis. Several vessels were occluded by the infiltration of these cells. A diagnosis of angiocentric immunoproliferative lesions (Grade I), which was originally coined by Jaffe, was made. Complete remission was achieved by treatment with prednisolone and cyclophosphamide. This disease, which corresponds to lymphomatoid granulomatosis, is graded into three categories depending on the severity of cytologic and histologic malignancy. Although it has recently been suggested that its pathogenesis may be related to EB-virus infection, ATL-virus may have been a contributory factor in this case.
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PMID:[A case of angiocentric immunoproliferative lesions in an ATL-virus carrier]. 791 63

Parainfluenza viruses are a major cause of hospitalization for respiratory illness in children. The spectrum of clinical illness associated with infection due to parainfluenza type 4 virus has not been well defined. It is technically difficult to isolate the virus in tissue culture, and because illness is generally reported to be mild, in many cases, patients may not seek medical attention. We describe a series of 10 children with parainfluenza type 4 virus infection who were seen at the Montreal Children's Hospital between 1988 and 1992. There were five males and five females whose average age was 29.7 months. Infection was associated with symptoms of bronchiolitis or pneumonia in 5 children, paroxysmal coughing in 3 infants, apnea in 1 newborn, and aseptic meningitis in 1 child. Hospitalization was required for 8 of the 10 children. It appears that infection with parainfluenza type 4 virus may be more common than previously recognized, and it may be associated with more severe infections.
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PMID:Infections due to parainfluenza virus type 4 in children. 811 Sep 59


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