Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinical introductionA 63-year-old woman recently diagnosed with lung metastasis, after routine chest radiography, was admitted to our hospital for unspecified symptoms, such as dyspnoea on minimal exertion and dry cough. Physical examination showed uncommon signs. The electrocardiogram showed sinus rhythm and incomplete left bundle branch block. Thoracic CT scan revealed bilateral lung and pleural metastases and pelvic CT showed a right femoral bone mass. Transthoracic echocardiography revealed a heterogeneous mass, lateral to the right ventricle, with pericardial effusion. Further, cardiac MRI (cMRI) was performed (figure 1A,B). Diagnosis was completed with an ultrasound-guided biopsy and histopathological examination (figure 1C,D).heartjnl;106/3/202/F1F1F1Figure 1(A,B) Cardiac MRI: asterisk is suggestive of fluid and the white arrow indicates fibrous encapsulation by LGE, (C) H&E stain:white arrow indicating a tumoral cell with atypical mitosis and (D) immunohistochemical staining for smooth muscle actin antibody. QUESTION: Which of the following is the most likely diagnosis?Pericardial lymphoma.Pericardial leiomyosarcoma.Pericardial cyst.Secondary malignant cardiac tumour.Pericardial teratoma.
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PMID:A 63-year-old woman with multiple secondary tumours. 3191 42

Mature cystic teratoma (MCT) is a benign, slow-growing tumor and accounts for approximately 75% of mediastinal germ cell tumors. Patients with MCT are often asymptomatic when the tumors are small. Most of the symptoms are frequently related to compression of the mediastinal structures. We herein describe 3 adult cases of MCT. The patients were a 37-year-old man, a 35-year-old woman, and a 54-year-old woman. They were hospitalized with compression-related symptoms, such as chest pain, dyspnea, and cough. Findings from conventional chest radiograph, computed tomography (CT), magnetic resonance imaging were characterized. Conventional chest radiography still plays a major role in the initial evaluation of MCT, while CT remains the preferred modality for initial cross-sectional imaging evaluation of mediastinal lesions. However, thoracic magnetic resonance imaging provides more detailed and often definitive evaluation of mediastinal masses than CT because of its superior tissue characterization.
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PMID:Imaging findings of three cases of large mediastinal mature cystic teratoma. 3246 77

Intrapulmonary teratoma is a rare and little-known disease. The present case was that of an adolescent with recurrent cough and haemoptysis. Chest radiography revealed a mass on the left lung base, and computed tomography (CT) indicated a heterogeneous tumour with a fluid component, soft parts, fat, and calcifications in the left upper lobe. Upper left lobectomy was performed; histopathological findings confirmed a mature pulmonary teratoma.
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PMID:"Deceiving appearances": intrapulmonary teratoma-a diagnostic challenge. 3306 Sep 22


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